[PDF] Top 20 The Effect of Neoadjuvant Chemotherapy on ER, PR and HER 2 Expression in Breast Cancer
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The Effect of Neoadjuvant Chemotherapy on ER, PR and HER 2 Expression in Breast Cancer
... [1]. Breast cancer is the second most common malignant tumor in ...of breast cancer patients in China has accounted for ...worldwide breast cancer ...infected breast ... See full document
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<p>Insulin-like growth factor-1, metabolic abnormalities, and pathological complete remission rate in HER2-positive breast cancer patients receiving neoadjuvant therapy</p>
... kg/m 2 to de fi ne central obesity, according to the Chinese Medical Association criteria for MetS, which we believed applic- able for Chinese ...term effect of ... See full document
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Original Article Estrogen receptor (ER), progesterone receptor (PR), and HER2 expression pre- and post- neoadjuvant chemotherapy in primary breast carcinoma: a single institutional experience
... (neoadjuvant) chemotherapy with agents such as doxorubicin and cyclophospha- mide had historically been offered to patients with locally advanced disease with a goal of reducing tumor size to enable ... See full document
7
Negative genic switch of HER 2 in the primary tumor instead of the synchronous metastatic nodal lesions after neoadjuvant chemotherapy in a patient with primary HER2 positive breast cancer
... the HER-2 positive primary tumor prior to NAC may still harbor amplified HER2 ...HER2 expression between primary tumors and synchronous nodal metastases in the absence of chemotherapy, ranging ... See full document
5
Comparison of the efficacy and survival analysis of neoadjuvant chemotherapy for Her-2-positive breast cancer
... the Her-2 overexpression group (P = ...that Her-2 overexpression can increase pCR in NAC compared with luminal ...hormone-positive breast cancer is less sensitive to primary ... See full document
9
Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
... similar effect has been reported in endothelial cells submitted to ionizing radiation ...under chemotherapy were not ...Its expression is increased upon serum starvation of mesenchymal stem cells and ... See full document
14
Effects of core needle biopsy and subsequent neoadjuvant chemotherapy on molecular alterations and outcome in breast cancer
... 416 breast cancers and 1,156 healthy women in China found that breast tumor biopsy, albeit confirmed benign pathologically, was an independent risk factor of breast ... See full document
9
High Ki-67 and Vascular Endothelial Growth Factor (VEGF) Protein Expression as Negative Predictive Factor for Combined Neoadjuvant Chemotherapy in Young Age Stage III Breast Cancer
... protein expression; the depen- dent variables were chemotherapy ...receptor expression, Her-2/ neu expression, and p53 protein ...VEGF expression with neoadjuvant ... See full document
11
A Study on the effect of Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
... Invasive lobular carcinoma is the second most common histologic type after ductal carcinoma, accounting for 5-10% of all breast cancers. It is associated with a high rate of multifocality and bilaterality. LCIS is ... See full document
103
Effect of neoadjuvant chemotherapy regimen on relapse free survival among patients with breast cancer achieving a pathologic complete response: an early step in the de escalation of neoadjuvant chemotherapy
... adriamycin-based chemotherapy plus tax- ane (A + T), HER2-targeted therapy (AT + HER2), or pro- vider choice ...first chemotherapy treatment to the date of sur- gery, including a typical 4- to 6-week window ... See full document
10
Role of neo-adjuvant hormonal therapy in the treatment of breast cancer: a review of clinical trials
... hormonosensitive breast cancer are well ...of neoadjuvant endocrine therapy is much more recent and less reported in the ...about neoadjuvant endocrine treatment (tamoxifen and aromatase ... See full document
12
Evaluation of tumor malignancy in patients with HER-2 overexpression breast cancer after TCH and TAC neoadjuvant chemotherapy
... of HER-2-targeted recombinant DNA- derived humanized monoclonal antibody that selectively acts on HER-2 extracellular part and specifically blocks HER-2 receptor to exert ... See full document
5
Original Article High expression of GLUT1 and GLUT3 correlate with neoadjuvant chemotherapy ineffectiveness breast cancer patients
... for PR nor sufficient increase to qualify for ...on cancer staging manual (AJCC 7th edi- tion). ER, PR, Her-2 and Ki-67 status were rou- tinely analyzed by pathology department ... See full document
7
Original Article Prognostic value of hormone receptor status conversion following neoadjuvant chemotherapy in a series of operable breast cancer patients
... primary breast carcinoma treated with both NAC and surgery, which were diagnosed from 2008 to 2013 by needle core biopsy at Guangxi University Affiliated Tumor Hospital ...mammography, breast ultrasound, or ... See full document
9
Original Article Evaluation of biomarker changes after administration of various neoadjuvant chemotherapies in breast cancer
... the chemotherapy itself on immunohistochemical staining and factors related to the observing pathologist are other important ...on cancer cells. In conclusion, biomarker levels of ER, PR, HER2 ... See full document
8
Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67
... that HER-2 expression positivity was significantly associated with TMB (HER-2 positive vs HER-2 negative, OR = ...Ki-67 expression positivity (.14%) than those with ... See full document
7
Changes in aldehyde dehydrogenase 1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer
... ALDH1 expression was not associated with OS (P = ...this effect was seen independently of patients’ age, tumor stage, tumor grade or chemotherapy sequence (Table 4), and the data suggest that an ... See full document
13
Triple-negative (ER, PgR, HER-2/neu) breast cancer in Indian women
... (TN) breast cancer, which is defined as being negative for the estrogen receptor (ER), the progesterone receptor (PgR), and the human epidermal growth factor receptor 2 ... See full document
11
Utility of estrogen receptor alpha (ERα), progesterone receptor (PR), and her2 expression in primary breast carcinoma in Iraqi Women
... & PR) and human epidermal growth factor receptor 2 (HER2) status of a primary breast carcinoma have clinical importance in assessment of patient prognosis and treatment ...of breast tissue ... See full document
6
Role of p glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer a prospective clinical study
... After approval by the Institution Review Board and the ethical committee of the hospital, 50 fine needle aspira- tion cytology (FNAC) proven cases of LABC according to AJCC (American Joint Committee on Cancer) ... See full document
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