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[PDF] Top 20 The effect of route of administration in thymoquinone toxicity in male and female rats

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The effect of route of administration in thymoquinone toxicity in male and female rats

The effect of route of administration in thymoquinone toxicity in male and female rats

... to rats which received oral ingestion of TQ, data collected from experimental observations and analysis suggest that single oral ingestion of TQ in doses lower than 500 mg/kg body weight could be ...transient ... See full document

6

Effect of Chronic Aluminum Administration on Affective and Cognitive Behavior in Male and Female Rats

Effect of Chronic Aluminum Administration on Affective and Cognitive Behavior in Male and Female Rats

... the effect of chronic exposure of low doses of Aluminum on affective and cognitive disorders in male and female ...Twenty-five rats for each gender are used and the treatment carried out for 8 ... See full document

18

Evaluation of Effect of Momordica Dioica Extract on Reproductive System of Male and Female Rats

Evaluation of Effect of Momordica Dioica Extract on Reproductive System of Male and Female Rats

... suppressant effect of Momordica Dioica on pituitary gonadotropins, and direct toxic effect on follicular cells as seen with the seminiferous tubules in male ...rats. Administration of ... See full document

7

Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... oral administration of PD and CM to the both male and female ...Oral administration of PD and CD at three dose levels of 1000, 500 and 250mg/kg body weight did not produce significant changes ... See full document

9

Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

... acute toxicity, TQ that is loaded in nanostructured lipid carrier (NLC) was found to be less toxic than pure ...the toxicity of the compound. In the subacute toxicity study, oral ... See full document

11

Effect of Oxydemeton Methyl Toxin on Hormones Testosterone and Dihydrotestosterone in Adult Male Rats

Effect of Oxydemeton Methyl Toxin on Hormones Testosterone and Dihydrotestosterone in Adult Male Rats

... Wistar male rats weighing 190 ± 10% gr and age of 2/5-3 month were provided from the breeding center of laboratory animals of islamic azad university of Kazeroon branch .... Rats were placed in ... See full document

6

Effect of Metformin Against the Nicotinamide-Streptozotocin Induced Sperm Abnormalities in Diabetic Male Wistar Rats

Effect of Metformin Against the Nicotinamide-Streptozotocin Induced Sperm Abnormalities in Diabetic Male Wistar Rats

... in male diabetic ...T2DM male Wistar rats. The reproductive toxicity was evaluated by determining the caudal sperm shape abnormality, sperm count and weight of the ...the male ... See full document

8

<p>The Effect of Size, Dose, and Administration Route on Zein Nanoparticle Immunogenicity in BALB/c Mice</p>

<p>The Effect of Size, Dose, and Administration Route on Zein Nanoparticle Immunogenicity in BALB/c Mice</p>

... size-dependent effect is not found in this study (Figure 2). The possible accelerated clearance of zein nanoparticle resulted from repeated injections may be similar to those of polyethylene glycol (PEG)-modi fi ed ... See full document

12

EVALUATION OF PHARMACOKINETICS AND LIVER FUNCTION EVALUATED IN RATS FOLLOWING THE CO-ADMINISTRATION OF CAPTOPRIL AND CIPROFLOXACIN

EVALUATION OF PHARMACOKINETICS AND LIVER FUNCTION EVALUATED IN RATS FOLLOWING THE CO-ADMINISTRATION OF CAPTOPRIL AND CIPROFLOXACIN

... This effect may be due to displacement of captopril from its binding site to plasma proteins by ciprofloxacin as ciprofloxacin bind strongly to plasma proteins than ...manner. Administration of ... See full document

8

Evaluation of Hepatoprotective Effect of Hydroalcoholic Extract of Momordica Charantia Leaves in Carbon Tetrachloride-Induced Liver Toxicity in Wistar Rats

Evaluation of Hepatoprotective Effect of Hydroalcoholic Extract of Momordica Charantia Leaves in Carbon Tetrachloride-Induced Liver Toxicity in Wistar Rats

... body weight were used. The animals were obtained from the central animal house of SVS Medical college. Rats were kept in polypropylene cages provided with paddy husk bedding. Free access to food (standard pellets) ... See full document

6

Long-Term Administration of Artesunate Induces Reproductive Toxicity in Male Rats

Long-Term Administration of Artesunate Induces Reproductive Toxicity in Male Rats

... Methods: Adult male rats (n=6) were orally given artesunate (2.9 mg/kg body weight) on daily basis for five days. Artesunate (2.9 mg/kg body weight) was administered to another group of rats daily ... See full document

12

AQUEOUS ETHANOLIC EXTRACT OF ACALYPHA INFERNO LEAVES IS SAFE IN ANIMALS

AQUEOUS ETHANOLIC EXTRACT OF ACALYPHA INFERNO LEAVES IS SAFE IN ANIMALS

... They include terpenoids, glycosides, flavonoids, alkaloids, saponins, sterols and volatile oils 1 . With these diverse ingredients present, medicinal plants do not customarily aim at a particular ailment, but as a source ... See full document

8

Acute and chronic toxicities of Bacopa monnieri extract in Sprague Dawley rats

Acute and chronic toxicities of Bacopa monnieri extract in Sprague Dawley rats

... chronic toxicity test was conducted in accordance with WHO and OECD ...in rats, approximately 30 mg/kg/day, was calculated based on body surface area ...chronic toxicity evaluation. The rats ... See full document

10

The effect of hydro-alcoholic extract of ephedra pachyclada on serum concentrations of neuropeptide Y and ghrelin hormones and body weight in male rats

The effect of hydro-alcoholic extract of ephedra pachyclada on serum concentrations of neuropeptide Y and ghrelin hormones and body weight in male rats

... Neuropeptide Y (NPY) is considered as the most abundant peptide hypothalamus and its most important effect is stimulating food behavior. In other words, NPY gene is the candidate gene for obesity; it is the ... See full document

5

The concentration of ceruloplasmin in blood of tumor-bearing rats after administration of a dirhenium(III) compound and cisplatin

The concentration of ceruloplasmin in blood of tumor-bearing rats after administration of a dirhenium(III) compound and cisplatin

... In our previous works, the anticancer and an- tioxidant properties of cluster rhenium(III) com- pounds which were administered to tumor-bearing animals separately, with cPt, (Re – Pt system), in liposomal forms and in ... See full document

7

Joint Effect of Exercise and Water Extract of Cumin on Plasma Lipids in Hyper Cholesterolemic Male Sori Rats

Joint Effect of Exercise and Water Extract of Cumin on Plasma Lipids in Hyper Cholesterolemic Male Sori Rats

... the effect of cumin on lipid profile it should be mentioned that the results of this research agree with dhandapani and his colleagues ...the rats under cumin extract diet for 6 weeks ... See full document

5

Hepato-Protective Effect of  Folic Acid and Vitamin B12 in Comparison to N-Acetylcysteine in Experimentally Induced Acetaminophen Toxicity in Rats

Hepato-Protective Effect of  Folic Acid and Vitamin B12 in Comparison to N-Acetylcysteine in Experimentally Induced Acetaminophen Toxicity in Rats

... The institutional animal ethics committee approved the protocol of the study (Approval number: 289/2015/IAEC). 18 Adult, male Sprague dawley rats weighing 200-300g were housed at constant ambient ... See full document

7

Effect of Aqueous Extract of Caraway Seeds on Ghrelin Hormone In Male Rats

Effect of Aqueous Extract of Caraway Seeds on Ghrelin Hormone In Male Rats

... One day after the last injection, the rats were weighed and then were anesthetized with ether. blood samples were directly taken from the heart by the syringe 5 cc and blood serums were collected by centrifugation ... See full document

5

Hypertensive and Sympathomimetic Effects of the Methanol and Aqueous Extracts of Scoparia Dulcis in Anaesthetized Male Wistar Rats

Hypertensive and Sympathomimetic Effects of the Methanol and Aqueous Extracts of Scoparia Dulcis in Anaesthetized Male Wistar Rats

... The Ugo Basile double channel pen recorder was calibrated with a clinical sphygmomanometer and set at a recording speed of 10mm per second. Prior to the experiment, the recorder was left to equilibrate for about 1 hour ... See full document

9

Renoprotective Effect of Ipomoea Batatas Aqueous Leaf Extract on Cyclosporine-Induced Renal Toxicity in Male Rats

Renoprotective Effect of Ipomoea Batatas Aqueous Leaf Extract on Cyclosporine-Induced Renal Toxicity in Male Rats

... Renal toxicity is a common disease ...in rats. Forty male rats were distributed into 4 groups; Control (Cont), CE; rats intraperitoneal (IP) injected with CE (twenty-five mg/kg) for ... See full document

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