[PDF] Top 20 Effects of obesity on bone metabolism

... of obesity rates have doubled since 1980 [2] and as of 2007, 33% of men and 35% of women in the US are obese ...[3]. Obesity is positively associated to many chronic disorders such as hypertension, ... See full document

... The effects of obesity and caloric intake on biliary lipid metabolism were investigated in a series of related studies. The degree of saturation of gallbladder bile with cholesterol was found to be ... See full document

... The bone tissue is a dynamic tissue that is in a constant process of formation and resorption [6,7], and which requires the balance among several factors to ensure the maintenance of its structure and ... See full document

... ing these relevant aspects of chronic opioid treatment may lead to a number of comorbidities, such as hypogonadism and osteoporosis. Different studies have shown that both men and women chronically treated with opioids ... See full document

... the effects of ApN and its receptors have a positive role on bone metabolism, but some opposite aspects are also described ...a bone marrow cell culture with insulin or recombinant mouse ApN ... See full document

... independent effects of multiple comor- bidities, and environmental ...on bone metabolism and fracture risk [21, 39], with exception of the decreased serum levels of the bone formation marker ... See full document

... new bone formation in sleep-restricted rats decreased without reduction in bone resorption, leading to osteopenia ...lower bone mass. Nevertheless, both bone formation and resorption in rats ... See full document

... of bone metabolism under TNFis or non-TNFis during denosumab therapy in OP patients with RA to ...greater effects over the other drugs may include the following factors: 1) the differentiation of ... See full document

... the majority of studies were carried out using dual-energy X-ray absorptiometry technique which is not able to precisely distinguish between subcutaneous and visceral fat. The fact that most of the previously mentioned ... See full document

... To implement fractures of the tibia, each mouse was completely sedated with 1% pentobarbital sodium and placed supine on a surgical table (Taizhou Xintai Med- ical Equipment Manufacturing, Jiangsu, China). The hair on ... See full document

... deficiency bone loss and bone strength changes in ovariectomized (OVX) baboons (n = 7 per group) and the ALN mode of action at the tissue ...of bone turnover increased in OVX animals and were ... See full document

... results of Helin et al (23) and Sokol’nikov et al (24) (Tables 2 and 3). In some cases, warfarin causes a 50% increase in urinary excretion rather than affecting the absorption of calcium through the intestines. ... See full document

... using bone density measurements, and suggests high bone fragility in patients with ...higher bone fragility in diabetes are complex. Low bone turnover, accumulation of advanced glycation ... See full document

... The RANKL and OPG data in this study lend support to the hypothesis that Sal treatment attenuates bone loss in lupus/ GC-treated lupus mice partially through the RANK/RANKL/ OPG system. Third, our current data ... See full document

... a bone-derived phosphaturic hormone and a member of the FGF19 subfamily, which is expressed in osteoblasts/osteocytes in response to phosphate and vitamin D (35, 45, ...for bone homeostasis and ...and ... See full document

... new bone tissue (Nickols-Richardson, Miller, Wootten, Ramp, & Herbert, ...body bone mineral content and site-specific bone mineral density and bone mineral content among young ...enhance ... See full document

... prevents bone loss (41,42) ...of bone loss by Dz was attenuated by catechin treatment (Table ...the effects of catechin on animal models adopted drinking water containing 0·1 or 0·5 % green tea ... See full document

... levels of certain intestinal lactobacilli can increase weight and hyperglycemia in healthy adults, though the effects are strain- and dose-specific. Both the bacterial strain and the host are important in deter- ... See full document

... Childhood obesity has been linked to an increase in fracture risk, so the impact of obesity on bone metabolism is becoming a focus of attention to identify factors that may affect bone ... See full document

... side effects of the currently available anti-osteoporosis drugs, the development of herbal medi- cinal products to treat osteoporosis has become a global focus, and many studies of natural medicines have been ... See full document