[PDF] Top 20 Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection
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Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection
... subjects’ T cells recognized the highest ranking peptides, and few recognized the low-ranking ...contain T-cell ...in HIV with distinct clusters separated by regions where no epitopes have ... See full document
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Early Induction and Maintenance of Env-Specific T-Helper Cells following Human Immunodeficiency Virus Type 1 Infection
... acute HIV-1 infection prior to seroconversion, Env-spe- cific responses were often ...the HIV-1 Env-specific helper response following acute ...emerge early in acute ... See full document
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Multiple T-Cell Responses to Human Immunodeficiency Virus Type 1 Are Enhanced by Dendritic Cells
... from HIV-1- infected subjects enhance both monofunctional and polyfunc- tional CD8 ⫹ T-cell reactivity to single HIV-1 peptides repre- senting the minimal, optimal HLA A*0201 epitope ... See full document
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Nef-Mediated Resistance of Human Immunodeficiency Virus Type 1 to Antiviral Cytotoxic T Lymphocytes
... of nef on the immunogenicity and pathoge- nicity of HIV-1 infection suggests that this gene could be a target for enhancing cellular immunity in chronically infected individuals or the design ... See full document
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Human Endothelial Cells Enhance Human Immunodeficiency Virus Type 1 Replication in CD4+ T Cells in a Nef-Dependent Manner In Vitro and In Vivo
... modulate HIV-1-infected T cells. For example, while CD8 ⫹ T cells stimulated by professional APCs express early activation markers only transiently, EC-stimulated CD8 ⫹ ... See full document
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Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected with nef-Defective HIV Type 1
... controlling nef- defective HIV-1 strains and are therefore not required at com- paratively high levels in the SBBC or, alternatively, the lack of viral replication in the SBBC elicits lower levels of ... See full document
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Virus-Specific Interleukin-17-Producing CD4+ T Cells Are Detectable in Early Human Immunodeficiency Virus Type 1 Infection
... of virus-specific CD4 ⫹ T cells circulating in the blood, thus po- tentially explaining the lack of detection of IL-17-producing CMV-specific cells in peripheral blood of ... See full document
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Early Therapy of Vertical Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Control of Viral Replication and Absence of Persistent HIV-1-Specific Immune Responses
... that HIV- 1-specific immune responses are particularly ...of infection in the presence of high titers of passively acquired, maternal HIV-1-specific antibodies and/or the ... See full document
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Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ TEMRA Cells in Early Infection Are Linked to Control of HIV-1 Viremia and Predict the Subsequent Viral Load Set Point
... ⴙ T-cell responses to HIV-1 GAG early in infection is not a strong predictor of future viral load set ...whether HIV-1-specific CD8 ⫹ T-cell responses at ... See full document
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Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection
... acquired HIV-1 ...I/II HIV vaccine trials where the net cumulative cytotoxic T-lymphocyte (CTL) response rates were between 33 and 50%, as assessed by the chromium release assay (4, ...the ... See full document
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Selective Depletion of High-Avidity Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells after Early HIV-1 Infection
... high-avidity HIV-1- specific CD8 ⫹ T-cell responses primed during early infection, we performed a longitudinal analysis of the clonotypic compo- sitions of ... See full document
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Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination
... for human immunodeficiency virus type 1 (HIV-1) remains an elusive ...upon HIV-1 infection is ...an HIV-1 gag DNA vaccine recipient ... See full document
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Laboratory tests for detection of human immunodeficiency virus type 1 infection.
... and type of bands) seen on each strip, the WB result is inter- preted as positive, atypical or indeterminate (WBi), or nega- ...of infection and manifesting AIDS-related symptoms is ... See full document
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Productive and lytic infection of human CD4+ type 1 helper T cells with macrophage-tropic human immunodeficiency virus type 1.
... these cells were split into halves in anti-CD3 MAb-coated wells and an equal volume of the fresh medium containing IL-2 and IL-12 or IL-4 was added to the ...CD4 1 T-cell clones were generated from ... See full document
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Role of Human Immunodeficiency Virus (HIV)-Specific T-Cell Immunity in Control of Dual HIV-1 and HIV-2 Infection
... and HIV screening, were also tested. HIV testing was performed by HIV-1/HIV-2 enzyme immunoassay (Genescreen, version 2, HIV-1/HIV-2; Bio- Rad) after written ... See full document
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Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism
... wt HIV-1. After an additional 2 days, the cells were treated with GW4869 and spiroepoxide for 16 ...the HIV-1 CAp24 expression in activated CD4 ⫹ T lymphocytes from cocultures ... See full document
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Infection of nonlymphoid cells by human immunodeficiency virus type 1 or type 2.
... 4226 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Human epithelial cells L132 derived from embryonic lung and human lung fibroblasts MRC5 were infected by human immu[r] ... See full document
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Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo.
... that Nef enhances virus infectiv- ity, as determined by the efficiency of viral DNA synthesis rather than the level of binding or entry into target cells (2, 10, ...infected cells. Thus, these ... See full document
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CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.
... the virus designated HXBnPLAP, we inserted a placental alkaline phosphatase (PLAP) gene amplified by PCR in the nef site, replacing the lucif- erase gene in HXB-Luc ...ditis virus at the 5 9 end of ... See full document
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Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells
... of HIV-1 cannot induce their exclusion from virions as it does with huAPOBEC3G (data not ...inhibit HIV-1 infectivity to different ...lane 1), APOBEC3H (feA3H; lane 3), and APOBEC3CH ... See full document
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