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[PDF] Top 20 Entry of poliovirus into cells does not require a low-pH step.

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Entry of poliovirus into cells does not require a low-pH step.

Entry of poliovirus into cells does not require a low-pH step.

... However, a direct action of these agents in the initial steps of virus infection is still uncertain, because chloroquine was still active in the inhibition of foot-and-mouth disease viru[r] ... See full document

6

Endocytosis and a Low-pH Step Are Required for Productive Entry of Equine Infectious Anemia Virus

Endocytosis and a Low-pH Step Are Required for Productive Entry of Equine Infectious Anemia Virus

... that entry of some retroviruses into host cells is dependent upon a vesicle-localized, low-pH ...The entry mechanism of equine infectious anemia virus (EIAV) has yet to be ...EIAV ... See full document

7

The Avian Coronavirus Infectious Bronchitis Virus Undergoes Direct Low-pH-Dependent Fusion Activation during Entry into Host Cells

The Avian Coronavirus Infectious Bronchitis Virus Undergoes Direct Low-pH-Dependent Fusion Activation during Entry into Host Cells

... enable pH-independent, receptor-primed triggering of fusion activity in the case of coronaviruses (21, ...of pH-independent triggering of ...protein does not behave biologically as a canonical class ... See full document

9

Induction of Apoptosis by Sindbis Virus Occurs at Cell Entry and Does Not Require Virus Replication

Induction of Apoptosis by Sindbis Virus Occurs at Cell Entry and Does Not Require Virus Replication

... infected cells. To determine the step in virus replication during which apoptosis is triggered, we used UV- inactivated SV, chemicals that block virus fusion or protein synthesis, and cells that do ... See full document

7

HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

... thus does not reach preformed endosomes (66, ...and cells at the lower temperature, despite the presence of many previously internalized HIV-1 particles that were no longer susceptible to ...HIV-1 ... See full document

15

Activation of Fusion by the SER Virus F Protein: a Low-pH-Dependent Paramyxovirus Entry Process

Activation of Fusion by the SER Virus F Protein: a Low-pH-Dependent Paramyxovirus Entry Process

... BHK21 cells which transiently expressed SER virus F/HN glycoproteins were exposed to various temperatures for a brief ...when cells expressing SER virus F/HN glycoproteins were exposed to higher ... See full document

8

Is the 135S Poliovirus Particle an Intermediate during Cell Entry?

Is the 135S Poliovirus Particle an Intermediate during Cell Entry?

... during poliovirus entry into cells and are consistent with a model in which 135S particles are an inter- mediate of the viral entry ...infect cells in a PVR-indepen- dent manner is an ... See full document

5

Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells

Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells

... To assess whether i.c. infection with ZIKV results in tissue pathology, we analyzed tissue sections from the CNS of in- fected mice at peak disease by routine histology and immu- nohistochemistry. Compared with ... See full document

15

Protection of the Villus Epithelial Cells of the Small Intestine from Rotavirus Infection Does Not Require Immunoglobulin A

Protection of the Villus Epithelial Cells of the Small Intestine from Rotavirus Infection Does Not Require Immunoglobulin A

... A role for IgM in protection from rotavirus challenge cannot be ruled out but is unlikely. Antirotavirus IgM was detected in the serum of IgA knockout mice, but rotavirus-specific IgM was detected in fecal samples from ... See full document

8

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

... by low pH ...while entry studies using HCVpp and HCVcc have yielded remarkably convergent results, some features may ...extend entry studies to in vivo-produced viruses and other cell types, ... See full document

8

Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry

Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry

... 17Cl-1 cells by MHV-A59 and the influence of the above substances, we used the plaque assay (see Materials and ...as low as 10 nM for concanamycin A, 100 nM for bafilomycin A1, and 10 ␮ M for monensin ...of ... See full document

11

Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG I

Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG I

... Hepatitis C virus (HCV) infects nearly 200 million peo- ple worldwide [1]. HCV infection causes chronic liver disease, cirrhosis, and is associated with hepatocellular carcinoma [2]. It is estimated that only 15-40% of ... See full document

8

Exit from Host Cells by the Pathogenic Parasite Toxoplasma gondii Does Not Require Motility

Exit from Host Cells by the Pathogenic Parasite Toxoplasma gondii Does Not Require Motility

... internal pressure and membrane stretching in the RBC. As with T. gondii, the exact mechanism by which the parasites rupture the membrane is not known, but as mentioned above, Plasmodium egress has been shown to be ... See full document

10

Low Endocytic pH and Capsid Protein Autocleavage Are Critical Components of Flock House Virus Cell Entry

Low Endocytic pH and Capsid Protein Autocleavage Are Critical Components of Flock House Virus Cell Entry

... cell entry remains poorly defined; however, common themes are ...(FHV) entry and membrane penetration. We demonstrate that low endocytic pH is required for FHV infection, that exposure to ... See full document

10

Initial Binding of Murine Leukemia Virus Particles to Cells Does Not Require Specific Env-Receptor Interaction

Initial Binding of Murine Leukemia Virus Particles to Cells Does Not Require Specific Env-Receptor Interaction

... a low infectious titer compared with the physical number of particles may be the rate of particle collision with the cell ...on cells may not meet the target cells because their movement is re- ... See full document

13

Selective killing of transformed rat cells by minute virus of mice does not require infectious virus production.

Selective killing of transformed rat cells by minute virus of mice does not require infectious virus production.

... The data indicate that cell killing by MVM is independent of infectious virus production and thus support the notion that the preferential cytolytic effect is affected by viral cytotoxic[r] ... See full document

5

Minimum internal ribosome entry site required for poliovirus infectivity.

Minimum internal ribosome entry site required for poliovirus infectivity.

... 67, 1993 MINIMUM INTERNAL RIBOSOME ENTRY SITE FOR POLIOVIRUS It has been previously reported that in vitro translation of PV mRNAs in RRL results in the production of spurious translatio[r] ... See full document

11

Poliovirus tropism and attenuation are determined after internal ribosome entry

Poliovirus tropism and attenuation are determined after internal ribosome entry

... adherent cells were infected at a multiplicity of 10 PFUs per cell with adenoviruses encoding bicistronic ...the cells were lysed in 1 ml pas- sive lysis buffer (PLB; Promega ...from cells infected ... See full document

12

Preexisting Immunity to Poliovirus Does Not Impair the Efficacy of Recombinant Poliovirus Vaccine Vectors

Preexisting Immunity to Poliovirus Does Not Impair the Efficacy of Recombinant Poliovirus Vaccine Vectors

... by poliovirus protease recognition ...recombinant poliovirus that expresses the C-terminal half of chicken ovalbumin (Polio-Ova) protected 100% of the immu- nized mice against challenge with lethal doses of ... See full document

6

Initial Events in Infectious Salmon Anemia Virus Infection: Evidence for the Requirement of a Low-pH Step

Initial Events in Infectious Salmon Anemia Virus Infection: Evidence for the Requirement of a Low-pH Step

... the low pH of endosomes, an apolar fusion peptide is exposed on the surface of the hemagglutinin molecule ...at low pH (29). When ISAV was incu- bated with cells at reduced pH, ... See full document

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