[PDF] Top 20 Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man
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Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man
... electrophoretic mobility, a higher density, higher free cholesterol content, and a higher proportion of sphingomyelin and lysophosphatidylcholine in the phospholipid fraction. A number of lower molecular weight ... See full document
11
Preparation of a Human Standard for Determination of the Levels of Antibodies to Oxidatively Modified Low-Density Lipoproteins
... against oxidatively modified low- density lipoproteins (oxLDL) in the pathogenesis of athero- sclerosis is, presently, the object of intense ...atheromatous lesions (5, 12, 22), and LDL ... See full document
6
Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low density lipoprotein Proposed role for arterial wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins
... to lipoprotein aggregation (15), an impor- tant atherogenic event (see Introduction, and 2, 9–11), the overall goal of the present study was to seek evidence for an arterial wall SMase acting on LDL ... See full document
11
Macrophage derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low density lipoproteins, and contain oxidation specific lipid protein adducts
... the atherosclerotic lesions from the ballooned rabbits as well as the MFC isolated from the same lesions in the presence of antioxidants, exhibited positive immunoreactivity with polyclonal ... See full document
11
Presence of hypochlorite modified proteins in human atherosclerotic lesions
... B–rich lipoprotein frac- tion from other proteins present in ...the density was adjusted with KBr to r 5 ...peroxidase-conjugated rabbit anti–sheep immunoglobulins (3:40,000 dilution, Dakopatts, ... See full document
11
Carbohydrate composition of circulating multiple-modified low-density lipoprotein
... CA, USA). Six milliliters of NaBr solution (d = 1.019 g/mL) was layered over the plasma and centrifuged for 2 hours at 116763 g (42000 rpm) in a Type 50Ti rotor (Beckman Instruments). The lower layer of LDL (1.5 cm over ... See full document
7
Lipid composition of circulating multiple-modified low density lipoprotein
... Total lipids were extracted from LDL using a previously described method [13] in chloroform-methanol 1:2 (v/v) mixture. 20 μl of 14 C-labelled cholesterol in methanol (1 μCi/ml) was added to samples for future low ... See full document
6
Lipoprotein proteoglycan complexes induce continued cholesteryl ester accumulation in foam cells from rabbit atherosclerotic lesions
... from atherosclerotic lesions metabolize lipoprotein-proteoglycan complexes predominantly via receptor- mediated endocytosis and consequently continue to accumulate intracellular cholesteryl ... See full document
9
Malondialdehyde modified low density lipoproteins in patients with atherosclerotic disease
... controls). Modified LDL, isolated from pooled LDL of 10 patients, showed a higher electrophoretic mobility on agarose gels, a higher content of thiobarbituric acid reactive substances, and a higher ... See full document
10
Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin
... not modified APOE genotypes effects, therefore this vari- able was not included in the regression ...the presence of ε2 allele was associated with a sig- nificant decrease of ...hand, presence of ε 4 ... See full document
11
The Evolution of lipid Metabolism in Iraqi Children with Nephrotic Syndrome
... high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) were determined in a study of 42 Iraqi children, half of which ... See full document
8
Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
... mechanisms that promote oxidation in vivo have not been identified. Myeloperoxidase, a heme protein secreted by activated macrophages, generates reactive intermediates that oxidize lipoproteins in vitro. To explore the ... See full document
9
Significance of low density lipoprotein production in the regulations of plasma cholesterol level in man
... of low density lipoprotein (LDL) is the major factor controlling LDL concentrations in subjects with plasma cholesterol levels from low- normal to mildly elevated, measurements of apoprotein ... See full document
11
CAROTENOIDS IN MAN THE DISTRIBUTION OF EPIPHASIC CAROTENOIDS IN ATHEROSCLEROTIC LESIONS
... To test the validity of this plan of grading, the specimens were assayed for total cholesterol since cholesterol is the major lipid found in atherosclerotic plaques 3-6, and because prev[r] ... See full document
6
ANTI-HYPERLIPIDEMIC ACTIVITY OF LEAVES OF Sphaeranthus indicus ON ATHEROGENIC DIET INDUCED HYPERLIPIDEMIC IN RATS
... The powdered leaf material was subjected to batch extraction in Soxhlet apparatus. The solvent used was 95% Methanol. The powdered leaf of Sphaeranthus indicus was evenly packed in Soxhlet extractor for extraction with ... See full document
5
“Study of Wattakaka Volubilis on Tissue Lipids and Antioxidants in Aluminium Sulphate Exposed Rats” by S.Usha Rani, R.Anuradha, India.
... Antioxidant enzymes were measured by Catalase(CAT) 32 , Super oxide dismutase (SOD) 33 , Lipid peroxidation (LPO) 34 , Reduced glutathione (GSH) 35 , Glutathione peroxidase (GPx) 36 and Glutathione reductase (GR) 37 ... See full document
6
High Density Lipoprotein Metabolism in Man
... I-high density lipoprotein (HDL) was examined in a total of 14 studies in eight normal volunteers in an attempt to determine the metabolic relationship between apolipoproteins A-I (apoA-I) and A-II ... See full document
14
A Comparative study of Lipid Profile among Smokers and non Smokers
... Duration of Smoking and Lipid Profile The values of serum triglycerides, cholesterol and VLDL were higher in those subjects smoking cigarettes/ biddies for more than 15 years as compared to those who smoked for 10-15 ... See full document
6
A modified formula for calculating low-density lipoprotein cholesterol values
... TG × 20%. In the formula, the concentration of very low- density lipoproteins (VLDL) is estimated as 20% of total TG concentrations [4]. However, the particles found in patients with hypertriglyceridemia ... See full document
5
Original Article Beta-migrating very low-density lipoprotein conjugates with acrolein in high-cholesterol diet-fed rabbits and localizes to atherosclerotic lesions with macrophages
... in atherosclerotic le- sions was an end product that originated from native LDL from the circulatory system ...in rabbit was induced by high- cholesterol diet fed in the same manner as MDA-conju- gated ... See full document
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