[PDF] Top 20 Evolution of Tumor Model: From Animal Model of Tumor to Tumor Model in Animal
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Evolution of Tumor Model: From Animal Model of Tumor to Tumor Model in Animal
... Julien, et al., “Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer,” Clinical Cancer Research: An O[r] ... See full document
15
New construction of an animal model for the orthotopic transplantation of an ovarian tumor
... a model have been reported, such as subcutaneous, peritoneal, and orthotopic transplant- ation of ...transplanted tumor models, the orthotopic transplanted tumor model can better reflect the ... See full document
6
Wounding promotes ovarian cancer progression and decreases efficacy of cisplatin in a syngeneic mouse model
... increased tumor growth since actively dividing cells are most susceptible to chemotherapeutic ...time from surgery to initiation of chemotherapy in advanced ovarian carcinoma, Tewari et ...mammary ... See full document
12
Evaluation of cloned cells, animal model, and ATRA sensitivity of human testicular yolk sac tumor
... ATRA as natural and synthetic derivatives of vitamin A can bind to the nuclear receptors, involved in the reg- ulation of embryonic development, organogenesis, cell homeostasis, cell growth, differentiation and apoptosis ... See full document
12
Intravesical administration of exogenous microRNA-145 as a therapy for mouse orthotopic human bladder cancer xenograft
... cancer model was established by inoculating 253J B-V cells into the bladder wall of ...of tumor growth, with a significant prolongation of animal survival (p = ... See full document
8
Anti-Tumor Potency and Toxicology of an Indian Ayurvedic Plant, Hygrophila Spinosa
... gland tumor in rodent has been widely used as an animal model for development of chemo-preventive drugs for breast cancer in humans (1, ...DNA from oxidative damage, inhibiting carcinogen ... See full document
11
The 150 most important questions in cancer research and clinical oncology series: questions 86–93
... dying from cancer, the time from diagnosis to death is often much shorter than the long period preceding ...engineered animal models that may not recapitulate the natural history of human ... See full document
7
Behavioral Characteristics of a Mouse Model of Cancer Pain
... before tumor inocu- lation, and that vehicle treated mice maintained high threshold responsiveness to mechanical stimulation in all ...a tumor in the hind paw ... See full document
8
Photosensitizer and peptide-conjugated PAMAM dendrimer for targeted in vivo photodynamic therapy
... Abstract: Challenges in photodynamic therapy (PDT) include development of efficient near infrared-sensitive photosensitizers (5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphine [PS]) and targeted delivery of PS to the ... See full document
14
T cell receptor (TCR) transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFβ) signaling mediate superior tumor regression in an animal model of adoptive cell therapy
... The DN TGFβ RII transgene has been demonstrated to be an effective strategy to circumvent the inhibitory effect of TGFβ. Upon TGFβ binding to the extracellular region of the TGFβ receptor complex, intracellular kinase ... See full document
8
Tumor intrinsic PIK3CA represses tumor immunogenicity in a model of pancreatic cancer
... on tumor cells has been shown to enhance antitumor T cell responses and promote tumor regression (12, 39, ...on tumor cells poten- tially can result in T cell exhaustion and augment tumor ... See full document
14
Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma
... the tumor cells following treatments, all animals in late treatment groups (days 8–21) showed significant decrease in cell migration/invasion in comparison to corresponding vehicle-treated ...developed ... See full document
15
A 5-fluorouracil-loaded floating gastroretentive hollow microsphere: development, pharmacokinetic in rabbits, and biodistribution in tumor-bearing mice
... a tumor-bearing animal model after oral ...in tumor-bearing mice model to investigate the amount of 5-FU that is delivered to main organs and ...in tumor and main organs ... See full document
12
APPLICATIONS OF PROTEOMICS IN ANIMAL MODEL
... in animal models These studies were conducted on transgenic Caenorhabdatis ...invertebrate model to study the role of Aβ aggregations, oxidized stress and cell ...and tumor necrosis factor related ... See full document
14
Optimal definition of biological tumor volume using positron emission tomography in an animal model
... derived from methods I – III, ...Two tumor contouring attempts (ROI blue and ROI magenta) using PET/SPECT edge contour function were demonstrated in axial (right), sagittal (middle), and coronal (left) ... See full document
10
Antitumor activity of methanolic extract of vernoniacinerealess by animal model
... by animal model, the various parameters such as heamatological studies and protein estimation, solid tumor volume, median survival time (MST), life span ...solid tumor volume was reduced ... See full document
6
Forecasting the Bladder Tumor Size and Immune Response of a Patient Over the Time Using a Dynamic Mathematical Model
... its evolution for particular patients is very difficult to find ...mathematical model that describes the bladder tumor growth and the immune response ...This model is customized for a single ... See full document
11
Anticancer activity of Ipomoea carnea on Ehrlich Ascites Carcinoma bearing mice
... The anti-proliferative effect of Ipomea carnea on EAC bearing mice was investigated. EAC bearing mice showed a marked reduction in Hb, RBC and WBC, whereas the EEIC treated group restored the above heamatological ... See full document
7
<p>Improving antitumor outcomes for palliative intratumoral injection therapy through lecithin–chitosan nanoparticles loading paclitaxel–cholesterol complex</p>
... the tumor volumes of tumor-bearing mice treated with saline and blank LCS_NPs were growing ...of tumor in PTX-CH-loaded LCS_NPs group was smaller than that in PTX group with a significant difference ... See full document
17
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin
... the tumor vasculature, we analyzed the levels of expression of a series of angiogenic factors by an angiogenesis-related protein array on wholeprotein extracts of ...evident from these results that ... See full document
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