• No results found

[PDF] Top 20 Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes

Has 10000 "Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes" found on our website. Below are the top 20 most common "Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes".

Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes

Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes

... an experimental model might provide insight into pathogenetic mechanisms operating in systemic lupus erythematosus where the importance of DNAanti-DNA immune complexes have been ... See full document

12

Targeting Toll like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus

Targeting Toll like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus

... with disease activity and severity in human SLE [49-52], and there are well documented case reports of patients who developed SLE-like clinical manifestations after treatment with IFN-α ...DNAse-sensitive ... See full document

11

Review article: BK virus in systemic lupus erythematosus

Review article: BK virus in systemic lupus erythematosus

... of anti-dsDNA appears to occur ex- clusively in SLE or Mixed Connective Tissue Disease whereas autoantibodies to histones are found in SLE, drug induced SLE and rheumatoid ...demonstrated ... See full document

11

Hypoxia-Sensitive Metal β-Ketoiminate Complexes Showing Induced Single Strand DNA Breaks and Cancer Cell Death by Apoptosis

Hypoxia-Sensitive Metal β-Ketoiminate Complexes Showing Induced Single Strand DNA Breaks and Cancer Cell Death by Apoptosis

... using complete RMPI 1640 medium. These were incubated for 24 hours at 37°C in an atmosphere of 5.0% CO2. Complexes were dissolved in dimethylsulfoxide and then further diluted with RMPI 1640 to obtained ... See full document

18

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

... Our study suggests that a vaccine endowed with high poly-specificity and linked to poly-functionality is the most efficient in preventing tumor growth. We did not aim to establish a threshold of poly-specificity or a ... See full document

13

Molecular characterization of the Corynebacterium pseudotuberculosis hsp60 hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice

Molecular characterization of the Corynebacterium pseudotuberculosis hsp60 hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice

... the DNA sequence of paralogs of ...the DNA sequence of the ...genomic DNA, 2 μM of each of the primers, 1 × PCR Buffer II and 1 U AccuPrime taq DNA ... See full document

10

Chromatin as a target antigen in human and murine lupus nephritis

Chromatin as a target antigen in human and murine lupus nephritis

... antigen-selective immune res ponse ...hypomethylated DNA is more immunogenic and can induce maturation of dendritic cells and potentially activate autoimmune T cells and B cells ...the DNA-binding ... See full document

9

Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant

Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant

... TTCTAGATCACTGAGAGCTGGGGTC-3 ′ . The PCR product was then digested by restriction enzymes Xba 1 and Hind 3, and inserted into backbone vector pVAX1 (Life Technologies, Carlsbad, CA, USA), which was digested by the same ... See full document

12

Construction of Mtb72F Plasmid as a DNA Vaccine Candidate for Mycobacterium tuberculosis

Construction of Mtb72F Plasmid as a DNA Vaccine Candidate for Mycobacterium tuberculosis

... Mtb72F is a recombinant protein vaccine against M. tuberculosis that provided protective immunity in mice, rabbits, guinea pigs, and monkeys (7-9). In response to immunization cellular immune responses were ... See full document

7

Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... UVC. Following DNA damage induction, cells were washed twice with ice-cold PBS and resuspended in 200 μl PBS. A mixture of 20 μL cell suspension and 75 μl of 0.5% low melting point (LMP) agarose were immediately ... See full document

5

Tetraaza[14]macrocyclic transition metal complexes as DNA intercalators

Tetraaza[14]macrocyclic transition metal complexes as DNA intercalators

... the DNA base pairs may additionally be supported by slightly higher hydrophobicity of the nickel complex in comparison to the copper derivative, which may be particularly important for groove ...The DNA LD ... See full document

10

Metal complexes as DNA intercalators

Metal complexes as DNA intercalators

... the DNA double helix. This DNA binding mode was first proposed by Lerman 1 to explain the strong affinity for DNA of certain heterocyclic aromatic dyes such as the ...the DNA double ...unwinds ... See full document

46

Efficient Transcription of a Compact Nucleoprotein Complex Isolated from Purified Simian Virus 40 Virions

Efficient Transcription of a Compact Nucleoprotein Complex Isolated from Purified Simian Virus 40 Virions

... Due to the relative simplicity of simian virus 40 SV40 nucleoprotein complexes and the ability to isolate SV40 DNA, DNA-histone minichromosome, and DNA-histone viral protein core complex[r] ... See full document

11

Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cells

Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cells

... deadly disease for many affected patients. The search for the novel anti-OS agent is extremely urgent and ...novel anti-OS agent. Here we characterized DNA-dependent protein kinase catalytic ... See full document

11

Diagnosis and activity assessment of immunoglobulin A nephropathy: current perspectives on noninvasive testing with aberrantly glycosylated immunoglobulin A-related biomarkers

Diagnosis and activity assessment of immunoglobulin A nephropathy: current perspectives on noninvasive testing with aberrantly glycosylated immunoglobulin A-related biomarkers

... IgG showed the best performance for diagnosis of IgAN, with a sensitivity of 89% and specificity of 92%. However, these findings also suggest that a panel of such serum biomarkers may be helpful to differentiate IgAN ... See full document

6

Marek's Disease Herpesvirus-Induced DNA Polymerase

Marek's Disease Herpesvirus-Induced DNA Polymerase

... The nuclear fraction of uninfected duck embryo fibroblasts contained about 2 and 3 units of activity per g wet weight of cells, respectively, for the polymerase activities that eluted at[r] ... See full document

11

DNA immunization of neonates induces immunity despite the presence of maternal antibody

DNA immunization of neonates induces immunity despite the presence of maternal antibody

... after DNA immunization, detectable im- mune responses did not occur in passively immune neonates given inactivated ...that DNA vaccines do provide a valuable means of inducing immunity in young ... See full document

6

Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease dependent pathway that does not activate cysteine protease P32

Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease dependent pathway that does not activate cysteine protease P32

... (CPT) induced apoptosis of Hep 3B cells in a time- and concentration-dependent ...II–DNA complexes. Unexpectedly, CPT-induced apoptosis in this cell type occurred without any detectable ... See full document

10

A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA binding state

A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA binding state

... testosterone-mediated events. These findings suggest that dihydrotestosterone may amplify the androgenic signal at its targets not only by its higher affinity for the receptor but also by its more efficient conversion to ... See full document

11

DNA Vaccine Using Mycobacterium bovis Ag85B Antigen Induces Partial Protection against Experimental Infection in BALB/c Mice

DNA Vaccine Using Mycobacterium bovis Ag85B Antigen Induces Partial Protection against Experimental Infection in BALB/c Mice

... M. bovis bacillus Calmette-Gue ´rin (BCG) is an attenuated strain of M. bovis and is presently the only available vaccine that can be used against bovine tuberculosis. However, the reported protective efficacies of BCG ... See full document

6

Show all 10000 documents...