[PDF] Top 20 Exposure to depleted uranium does not alter the co expression of HER 2/neu and p53 in breast cancer patients

... study, p53 immunoexpression was detected in ...1). P53 Immunoexpression was also detected in ...hand, p53 immunoexpression was detected in ...differentiated breast cancer) as compared ... See full document

... that breast cancer progression is often associated with alterations in expressions of ER, PR, HER-2/neu, p53 and ...and Her-2 leads to lower or absent hormone ... See full document

... gene expression was significantly increased in patients living in the areas of high risk DU expo‑ sure, in comparison to patient tumors from low risk areas [P = ...gene expression in endometrial ... See full document

... The HER 2 NEU gene is located on chromosome 17q and encodes for a tyrosine kinase receptor which is thought to control cell growth and development (122,123) ...transformation. HER 2 ... See full document

... of patients less than 50 years having HER-2/neu gene amplification was higher in our series (82/170; ...younger patients is lower ...referral patients or due to the diversity ... See full document

... mutant p53 expressions with topoisomerase IIα expression in basal-like breast cancer; although we didn’t find any significant association, but it showed that mutant p53-topoisomerase ... See full document

... score 2; ˃ 1-10%, score 3; ˃ 10- 33%, score 4; ˃ 33-66% and score5; ...or 2 through 8. A score of 0 -2 was regarded as negative, while 3-8 as ...cells; 2+; weak or moderate, complete brown ... See full document

... ating uranium in vivo. While EDTA can bind to multiple metals, uranium (VI) and EDTA complexes are unstable over pH ...chelating uranium in vivo and often served as a positive ... See full document

... primary breast cancer, including date and type of surgery, side, histopthological details (tumour size, histology, grade, margins, lympho- vascular invasion and lymph node status), stage, receptor status, ... See full document

... human cancer including breast cancer and have suggested that FAK overexpres- sion is an early event in tumorigenesis ...invasive cancer exhibited FAK over- ...every cancer specimen ... See full document

... of breast - the tumor diameter, lymph-node status, and thedegree of histological differentiation of the tumor which through the Nottingham scoring system incorporate two important elements - mitotic index and the ... See full document

... of cancer patients ...the cancer cells. For BC patients, it was associated with an unfavorable prog- nostic [48], especially for Tamoxifen-treated patients ...in patients with ... See full document

... Total RNA was extracted from Ishikawa cells stably transfected with pcDNA3.1 (+)-HER2 using TRIzol, as above. The same HER-2/neu primers were used as in the construction of pcDNA3.1 (+)-HER2. GAPDH ... See full document

... This is to certify that the dissertation entitled “CORRELATION OF ER, PR AND HER-2/neu WITH HISTOLOGICAL VARIANTS OF BREAST CARCINOMA” is a record of bonafide work done by DR. R.D. Puvitha, ... See full document

... positive expression rates of CD44st and HER-2 mRNA or protein in breast cancer ...and HER-2 were ...mRNA expression was evaluated using Spearman correlation ...the ... See full document

... gastric cancer, clinical trials on trastuzumab therapy for (metastatic) CRC are still ...the HER-2 overexpression and gene amplification to be a negative determinant in addition to KRAS mutation for ... See full document

... facilitate breast cancer recurrence of neu Anti- gen Negative Variant (ANV) tumors following initial rejection of the neu positive Mouse Mammary Carci- noma (MMC) tumor cells in ... See full document

... (Her- 2/Neu, also known as erbB2 and Her-2), encoded by c-erbB2 gene localized to chromosome 17q, is a 185 kDa membrane- spanning glycoprotein with tyrosine kinase ...Thus, ... See full document

... The hematoxylin and eosin stained slides of 43 EHBC patients were selected and the area of tumor was marked. The paraffin block corresponding to the selected slide was used to construct an EHBC tissue microarray ... See full document

... and 2 (MathSoft, Seattle, WA, USA), and all other analyses were performed using the STATA version 7 software (STATA Corporation, College Station, TX, USA) ... See full document