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18 results with keyword: 'faces ikzf b cell precursor acute lymphoblastic leukemia'

Protein kinase inhibitors for acute leukemia

ALL: Acute lymphoblastic leukemia; AML: Acute myelocytic leukemia; BCP- ALL: B-cell precursor acute lymphoblastic leukemia; BLK: B lymphocyte kinase; BTK: Bruton ’ s tyrosine

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2020
MYC as therapeutic target in leukemia and lymphoma

leukemia; pre T-LBL, precursor T-cell lymphoblastic leukemia/lymphoma; AML, acute myeloid leukemia; DLBCL, diffuse large B-cell lymphoma; ALL, acute lymphocytic leukemia; T-ALL,

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2020
The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia

IKZF1 gene defects are associated with inferior treatment outcome in both childhood and adult B-cell precursor acute lymphoblastic leukemia and occur in more than 70% of

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2021
T cell receptor gamma and delta rearrangements in hematologic malignancies  Relationship to lymphoid differentiation

T cell receptor delta gene recombinatorial events were found in 91% of acute T cell lymphoblastic leukemia, 68% of non-T, non-B lymphoid precursor acute.. lymphoblastic leukemia

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2020
Prediction of outcomes by early treatment responses in childhood T-cell acute lymphoblastic leukemia: a retrospective study in China

ALL: Acute lymphoblastic leukemia; T-ALL: T-cell acute lymphoblastic leukemia; B-ALL: B-cell acute lymphoblastic leukemia; MRD: Minimal residual disease; PR: Prednisone response;

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11
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2020
Pediatric T-Cell Acute Lymphoblastic Leukemia

Precursor T-cell lymphoblastic leukemia; T-cell acute lymphoblastic leukemia; T-cell ALL; T-ALL; T-cell receptor; thymocyte; transcription factor.. Clinics

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2021
Gerhard Zugmaier, et al. Medical Research Archives vol 9 issue 2.

Application of Mathematical Logic for Cytogenetic Definition and Risk Stratification of B-Cell Precursor Acute Lymphoblastic Leukemia

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2021
Proposal for the standardization of flow cytometry protocols to detect minimal residual disease in acute lymphoblastic leukemia

positive precursor B-cell acute lymphoblastic leukemia with positive minimal residual disease (0.32%) before conditioning treatment for hematopoietic stem cell transplantation?.

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2021
An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement

BCP-ALL: B-cell precursor acute lymphoblastic leukemia; CML: Chronic myeloid leukemia; HeH: High hyperdiploidy; FISH: Fluorescence in situ hybridization; mFISH: Multicolor FISH;

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2020
The role of tumor suppressor IKZF1 in leukemia development and therapy resistance

van Leeuwen (2017) Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B cell precursor acute lymphoblastic leukemia

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2021
Blinatumomab May Induce Graft Versus Host Leukemia in Patients with Pre-B ALL Relapsing After Hematopoietic Stem Cell Transplant

Blinatumomab, a bispecific T-cell engager monoclonal antibody used to manage Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia

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2021
Childhood pre B cell acute lymphoblastic leukemia with translocation t(1;19)(q21 1;p13 3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report

ACAs: Additional cytogenetic abnormalities; ALL: Acute lymphoblastic leukemia; aMCB: Array-proven high-resolution multicolor banding; B-ALL: B cell acute lymphoblastic leukemia;

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6
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2020
JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

ruxolitinib on the viability of PDX cells with JAK2 translocations in mono-culture, or in co-culture with primary MSCs. Mean±SEM of three JAK2 translocated samples is shown.

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2020
The pathobiology of pediatric B-cell precursor acute lymphoblastic leukemia

We aimed at the detection of recently identified tyrosine kinase fusion genes in 153 B-other cases of a population-based cohort of 574 Dutch/German pediatric BCP-ALL patients at

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2021
T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with NOTCH1 mutation as a good prognostic factor

Abbreviations: T/M-MPAL, T-lymphoid/myeloid mixed phenotype acute leukemia; ETP-ALL, early T-cell precursor acute lymphoblastic leukemia; AML-M0, minimally differentiated acute

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2020
Altered neutrophil immunophenotypes in childhood B‑cell precursor acute lymphoblastic leukemia

altered phenotypes on neutrophil lineage cells, but not on other relevant hematopoietic cell compartments (e.g. maturing monocytes and NRBC) which might also be abnormal,

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2020
Immunotherapy in hematologic malignancies: past, present, and future

ALL: Acute lymphoblastic leukemia; AML: Acute myeloid leukemia; BAFF: B cell-activating factor; BCMA: B cell maturation antigen; BiKE: Bispecific NK cell engager; BiTE: Bispecific

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2020
Aberrant ERG expression associates with downregulation of miR‐4638‐5p and selected genomic alterations in a subset of diffuse large B‐cell lymphoma

ERG+, aberrant ERG expression; AML, acute myeloid leukemia; T-ALL, T lymphoblastic leukemia; B-ALL, B lymphoblastic leukemia; DLBCL, diffuse large B-cell lymphoma; TMA,

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2021

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