[PDF] Top 20 Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.
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Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.
... Cogentech Cancer Genetic Test Laboratory; The Mayo Clinic Breast Cancer Patient Registry, Martine Tranchant, Marie-France Valois, Annie Turgeon, Lea Heguy, Phuah Sze Yee, Peter Kang, Kang In Nee, ... See full document
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Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
... comprehensive fine-scale mapping of this 17q22 breast cancer susceptibility locus using 517 SNPs chosen to give dense coverage across this ...the variants most strongly ... See full document
14
Identification of independent association signals and putative functional variants for breast cancer risk through fine scale mapping of the 12p11 locus
... Family Cancer Clinics and the clinical follow up study (which has received funding from the NHMRC, the National Breast Cancer Foundation, Cancer Australia and the National Institute of Health ... See full document
21
Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk
... for Cancer Control from Ministry Health, Labour and Welfare of Japan, by a research grant from Takeda Science Foundation, by Health and Labour Sciences Research Grants for Research on Applying Health Technology ... See full document
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Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
... the Cancer Risk Clinic for their contributions to this resource, and the many families who con- tribute to our ...UPENN Breast Cancer Research Foundation; Susan ...Familial Cancer ... See full document
19
Fine-mapping of the 1p11.2 breast cancer susceptibility locus
... Fine-scale mapping of the susceptibility regions identified by GWAS has the potential to further narrow down the relevant area of interest, identifying additional risk SNPs, and predict- ing ... See full document
15
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
... a risk that is ...a risk that is ~3-fold ...to breast cancer is consistent with results from GWAS in other complex disorders such as schizophrenia, using a different analytical approach 60 ... See full document
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Fine mapping of prostate cancer susceptibility loci in a large meta analysis identifies candidate causal variants
... susceptibility locus, any one (or more) of a large number of variants within the region may underlie the molecular mechanism that modulates ...correlated variants in linkage disequilibrium (LD) that ... See full document
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Genome-wide association studies of cancer: current insights and future perspectives.
... harbours multiple independent loci with distinct tumour specificities for CRC, glioma, CLL, MM, HL, and prostate, breast, and bladder cancers within the same TAD ...these cancer associations ... See full document
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Fine-mapping identifies multiple prostate cancer risk loci on 5p15 some associating with TERT expression
... PrCa risk and the imputed dataset of 1094 SNPs were assessed using a 1 df trend test adjusted for study and six principal components to correct for inflation ...PrCa risk at P , 10 25 (Supplementary Mater- ... See full document
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Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus.
... traditional fine-mapping approaches and are associated with CASP8 expression differences in normal breast ...and breast cancer cell lines, and binds multiple transcription ... See full document
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Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus.
... traditional fine-mapping approaches and are associated with CASP8 expression differences in normal breast ...and breast cancer cell lines, and binds multiple transcription ... See full document
45
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
... Endometrial Cancer Study (BECS) was partly funded by the ELAN fund of the University of ...endometrial cancer. The Mayo Endometrial Cancer Study (MECS) and Mayo controls (MAY) were supported by ... See full document
15
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
... (COGS), Cancer Research UK (C1287/A10118, C1287/A 10710, C12292/A11174, C1281/A12014, C5047/A8384, C5047/A15007 and C5047/A10692), the National In- stitutes of Health (CA128978) and Post-Cancer GWAS ... See full document
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Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
... Swedish Cancer Society (num- ber 11 0439). The Cancer Hormone Replacement Epidemiology in Sweden Study (CAHRES, formerly called The Singapore and Swed- ish Breast/Endometrial Cancer Study; ... See full document
15
The relationship between common genetic markers of breast cancer risk and chemotherapy induced toxicity : a case control study
... genetic variants are confirmed to be associated with breast ...that breast cancer susceptibility variants may also be asso- ciated with chemotherapy-induced toxicity through shared ... See full document
14
Breast cancer risk assessment with five independent genetic variants and two risk factors in Chinese women
... Absolute risk was also calculated to evaluate the com- bined effects of the five SNPs and the two risk factors by a modified Gail model and a 65-year absolute risk for breast cancer ... See full document
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The precision relationships between eight GWAS-identified genetic variants and breast cancer in a Chinese population
... in breast patients and controls and their association with overall breast cancer ...of breast cancer, we found three of the eight SNPs are significantly associated with overall ... See full document
11
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology.
... Genome-wide association study identifies multiple loci associated with bladder cancer risk. 704[r] ... See full document
28
Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21
... after Cancer Treatment, Department of Oncology, Oslo University Hospital, Oslo, Norway and Department of Oncology, Oslo University Hospital, Oslo, Norway), ...for Cancer Research and Department of Oncology, ... See full document
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