[PDF] Top 20 Formulation and evaluation of eletriptan hydrobromide pellets

... hrs and followed by pH 7.4 phosphate buffer for 10 hrs were taken as dissolution media, the temperature being maintained at 37±0.5 0 C throughout the study, 1ml sample of dissolution medium were withdrawn at ... See full document

... administration. Pellets can be prepared by many methods, the compaction and drug-layering being the most widely used ...comparative evaluation among these polymers and excipients and to assess the effect of ... See full document

... the pellets, to study the effect of crosscarmellose sodium, on ...The pellets were prepared by use of combination of Avicel PH 101 and lactose that indicated good flow ...the evaluation parameters, ... See full document

... improved formulation of lansoprazole enteric coated pellets [delayed ...The formulation process was carried out in FBP by solution -suspension layering technique and comparing it with marketed dosage ... See full document

... The formulation of antispasmodic agent in pellet, is to improve its oral bioavailability and possibility to restrict its absorption at colon, pellets were prepared by drug layering technique in three trails ... See full document

... Ajay L. et al., (2010) this work aims at investigating different types and levels of hydrophilic matrixing agents, including sodium alginate (Alg), and Hydroxypropyl methyl cellulose K15M (HPMC K15M) in an attempt to ... See full document

... The present investigation was undertaken to formulate budesonide controlled release pellets 1% w/w in capsules for treatment of Crohn’s disease. Drug excipient compatibility studies were conducted and found all ... See full document

... Differential Scanning Calorimetry (DSC) studies were carried out using DSC 60, having TA60 software, Shimadzu, Japan. The DSC thermograms were recorded for pure drug, HPMC E15, Maltodextrin, Drug and HPMC mixture and ... See full document

... In coating process the enteric coating was done with the percentage build ups of 22, 24, 26, and 28 with 8% sub coating. Acid resistance was failed up to 26% but at 28% build up acid resistance was passed. But for safer ... See full document

... Glibenclamide pellets were formulated by Extrusion- spheronization method by using solid dispersion drug, microcrystalline cellulose as spheronization aid, crosspovidone and sodium starch glycolate as super ...the ... See full document

... prepared pellets (M1 –M9) are subjected to in vitro release studies in ...optimized formulation M9 was used to compare with marketed formulation MEVA SR as shown in Figure 3, which indicated that the ... See full document

... of bitter drugs used for pediatric formulations. Palatability is defined as the property of being acceptable to the mouth ‘TASTE’ and acceptability to the mind or feelings acceptability. Generally Acceptable size of ... See full document

... from pellets coated with ethyl cellulose was shown in ...HCl pellets disintegrate rapidly in dissolution medium and release their drug content within 10 ...those Pellets coated to weight increases of ... See full document

... From the study, it can be shows that the SEM photographs and calculated sphericity factor confirmed that the prepared formulations were spherical in nature. Stability studies indicated that pellets are stable. ... See full document

... drug-containing pellets were further coated to achieve the required release ...coated pellets were characterized with regard to the percentage yield, density, friability, sphericity, drug entrapment ... See full document

... The compatibility studies were carried out by taking a mixture of drug and excipients at the ratio 1:1 or the probable ratio of usage in the current formulation. Individual excipients and API-Excipient mixtures ... See full document

... of pellets high drug loading but it also can be used to produce extended-release pellets in certain situations in a single step and thus can obviate the need for subsequent film ... See full document

... optimized formulation (DLSL6) which was selected based on entrapment efficiency is shown in Figure ...liposomal formulation zeta potential value was more than -50 mV, which suggest that the ... See full document

... Drug Loading Process: The drug loading process was identified as a critical step in the manufacturing process, as this step directly impacts upon size of pellets as well as the content uniformity of final product. ... See full document

... SEM analysis of the microspheres revealed that all the prepared microspheres were discrete, spherical in shape and had satisfactory surface morphology. The in-vitro release study of all formulations showed a retarded ... See full document