[PDF] Top 20 Functional characterisation of HLA-F

... o f anti-HLA-F monoclonal antibody production was based on the generation of the HLA-F ectodomain from recombinant proteins expressed in ...of HLA- B27 and human (32m transgenic ... See full document

... of HLA class II isotype expression were similar in CD2+, CD4+ and CD8+ subgroups of T ...1979). HLA-DR, -DQ and -DP molecules are differentially expressed on T cells after stimulation (Robbins e ta ...were ... See full document

... accelerate functional characterisation as it requires just one cross to create complete knock-out mutants (Figure ...this F 1 , phenotyping of ... See full document

... the enzymatic cleavage of phosphatidylinositol (PI) and phosphatidylinositol 4- monophosphate (PI(4)P) but it never cleaves 3-phosphoinositides. Moreover, Ca 2+ is essential to be present at the catalytic site and the ... See full document

... In this paper, we have described the phylogenetic and molecular/structural characterisation of the AChE pro- tein from S. japonicum. These findings improved the un- derstanding of the biological function of AChE ... See full document

... 150 Caco2 cells (183, 188). It is believed that this subfamily plays an important role in pathways of metabolism with Oat1 -/- mice resulting in defects in the handling of important metabolites (222, 223). Following, ... See full document

... the site of surgery clean. A small transverse incision of 3-5 mm was made through the outer layer of the skin on the lateral ventral surface of the frog (Fig. 2.1A). To reach the ovary wall, another incision was made ... See full document

... practice. Characterisation as a function of temperature is usually conducted in an oven or thermal chamber; in this study, we also report self-heating as a parameter in stability testing and ... See full document

... insecticides that act as conformation-sensitive activators of insect ryanodine receptors (RyRs). Both compounds are registered for use against lepidopteran species such as the diamondback moth, Plutella xylostella, a ... See full document

... We have now identified human and mouse breast epithelial SP cells and have shown that they constitute an undifferentiated subpopulation that can differentiate into ductal and lobular str[r] ... See full document

... Initially we adapted a cell-free extract model to specifically activate or inhibit the inflammatory caspases and then resolved control and inflammatory caspase activated proteomes on two[r] ... See full document

... whole-brain, functional imaging modalities, such as PET, SPECT or fMRI, single-technique approaches may be suffi- ...comprehensive characterisation of disease-specific ...increased functional and ... See full document

... Hildebrand’s laboratory. My first encounter with paint ball was enjoyable in Oklahoma. I am extremely thankful for the generous donation of soluble and biotinylated HLA proteins towards the project by Oklahoma ... See full document

... single HLA antigens has allowed us to define HLA antibody specificities to new ...antigen. HLA-specific antibodies recognize small clusters of non-self amino acid residues, which form ...different ... See full document

... Moreira, B., Ford, B., Ghosh, S., Harwood, W., Hassani-Pak, K., Hayta, S., Hickey, L. T., Kanyuka, K., King, J., Maccaferri, M., Naamati, G., Pozniak, C. J., Ramirez-Gonzalez, R. H., Sansaloni, C., Trevaskis, B., Wingen, ... See full document

... higher HLA-F expression have remarkably shorter OS in all grade gliomas and GBM in the CGGA RNA-seq set ...verify HLA-F expression as an independent prognostic factor (Table 1), univariate and ... See full document

... The MHC is a large cluster of 128 genes and 96 pseudogenes, located on the short arm of chromosome 6, many of which with important roles in the immune system. Traditionally, the MHC is divided into classes containing ... See full document

... P. teres is heterothallic in nature and can undergo sexual reproduction when two haploid cells of opposite mating types come together (McDonald 1963) to produce genetically recombi- nant haploid progeny (Fincham 1971). ... See full document

... By further manipulation of pathways involved in β-­cell development and utilization of a three dimensional culture system, recently three groups were able to differentiate PSCs to functional β cells in vitro. ... See full document

... two functional domains; an amino-terminal portion (33kDa) containing the dehydrogenase and cyclohydrolase activities, and a larger (67kDa) synthetase domain in the carboxy-terminal ... See full document