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[PDF] Top 20 Functioning outcomes with adjunctive treatments for major depressive disorder: a systematic review of randomized placebo-controlled studies

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Functioning outcomes  with adjunctive treatments for major depressive disorder: a systematic review of randomized placebo-controlled studies

Functioning outcomes with adjunctive treatments for major depressive disorder: a systematic review of randomized placebo-controlled studies

... 26 studies were included. All studies were acute (6–12 weeks) except for one 52-week ...self-rated functioning scale used in the included studies was the Sheehan Disability Scale ...13 ... See full document

13

Evaluation Efficacy and Safety of Vortioxetine 20 mg/d versus Placebo for Treatment Major Depressive Disorder: A Systematic Review and Meta Analysis of Randomized Controlled Trials

Evaluation Efficacy and Safety of Vortioxetine 20 mg/d versus Placebo for Treatment Major Depressive Disorder: A Systematic Review and Meta Analysis of Randomized Controlled Trials

... the review, we assessed values, Montgomery-Åsberg Depression Rating Scale (MADRS), Clinical Global Impression Scale-Improvement (CGI-I), Sheehan Disability Scale (SDS) and adverse effects randomized into ... See full document

11

Efficacy of ketamine in the rapid treatment of  major depressive disorder: a meta-analysis of randomized, double-blind, placebo-controlled studies

Efficacy of ketamine in the rapid treatment of major depressive disorder: a meta-analysis of randomized, double-blind, placebo-controlled studies

... Two reviewers extracted data independently using the afore- mentioned inclusion and exclusion criteria. For data that could not be directly retrieved, additional information was retrieved through correspondence with the ... See full document

9

Methodologies used in cost-effectiveness models for evaluating treatments in major depressive disorder: a systematic review

Methodologies used in cost-effectiveness models for evaluating treatments in major depressive disorder: a systematic review

... 37 studies were included in the review. These studies predominantly evaluated antidepressant ...pooled placebo-controlled comparative trials, single head-to-head trials, or ...of ... See full document

18

A systematic review of St. John’s wort for major depressive disorder

A systematic review of St. John’s wort for major depressive disorder

... established treatments and have been shown to be effective to treat depressive disorders, such as major depressive disorder ...treating depressive disorders [5]. A Cochrane ... See full document

25

New drug classes for the treatment of partial onset epilepsy: focus on perampanel

New drug classes for the treatment of partial onset epilepsy: focus on perampanel

... Perampanel is metabolized by first-order elimination pharmacokinetics. Elimination occurs primarily through the feces for approximately 70% of the dose. The remainder is excreted in the urine, with ,2% of the dose ... See full document

9

Sustaining remission of psychotic depression: rationale, design and methodology of STOP PD ΙΙ

Sustaining remission of psychotic depression: rationale, design and methodology of STOP PD ΙΙ

... another disorder, such as schizophrenia, schizoaffective disorder, brief psychotic disorder, or a toxic-metabolic encephalopathy, as a cause of their psychotic symptoms ... See full document

12

Quetiapine monotherapy in acute phase for major depressive disorder: a meta analysis of randomized, placebo controlled trials

Quetiapine monotherapy in acute phase for major depressive disorder: a meta analysis of randomized, placebo controlled trials

... Relative risks (RRs), the ratios of the probability of the event occurring in the experimental (intervention) group versus the controlled group, with the 95% confidence interval (95%CI) were used for synthesizing ... See full document

9

Vitamin C as an adjuvant for treating major depressive disorder and suicidal behavior, a randomized placebo controlled clinical trial

Vitamin C as an adjuvant for treating major depressive disorder and suicidal behavior, a randomized placebo controlled clinical trial

... A randomized double-blind, placebo-controlled 14-day trial of sustained-release ascor- bic acid including 42 healthy young adults showed that vitamin C (3,000 mg/day) increased mood measured by the ... See full document

8

Data-driven subtypes of major depressive disorder: a systematic review

Data-driven subtypes of major depressive disorder: a systematic review

... the outcomes of latent variable analyses; for instance, the included number of patients, and the severity and quantity of their symptoms obviously affect the result- ing latent classes and ...the studies, ... See full document

12

Comparative study between cryotherapy and salicylic acid in the treatment of plantar warts in Erbil - Iraq

Comparative study between cryotherapy and salicylic acid in the treatment of plantar warts in Erbil - Iraq

... significant association was found between duration of warts before treatment and cure rates. There was also a difference in the age of the populations in our study in comparison to other studies which may have a ... See full document

8

Neuronal connectivity in major depressive disorder: a systematic review

Neuronal connectivity in major depressive disorder: a systematic review

... fMRI studies. In these matrices, we inserted the number of studies that found a certain altered ...Several studies reported on relatively small subregions, eg, differentiated in a seed-based analysis ... See full document

23

Probiotics: Not Just for Treatment Anymore

Probiotics: Not Just for Treatment Anymore

... If probiotics continue to demonstrate potential as preventive therapies, several questions arise that are different from those concerning probiotics used as treatments. First, when probiotics are given prophy- ... See full document

6

Antibiotics and antiseptics for preventing infection in people receiving revision total hip and knee prostheses: a systematic review of randomized controlled trials

Antibiotics and antiseptics for preventing infection in people receiving revision total hip and knee prostheses: a systematic review of randomized controlled trials

... of systematic review of RCTs examining the effect of antibiotic and anti- septic prophylaxis solely on revision THA and ...been systematic reviews and meta-analysis that have examined the effect of ... See full document

9

Lamotrigine Adjunctive Therapy Among Children and Adolescents With Primary Generalized Tonic-Clonic Seizures

Lamotrigine Adjunctive Therapy Among Children and Adolescents With Primary Generalized Tonic-Clonic Seizures

... 24 placebo) pa- tients 2 to 19 years of age were randomly assigned and received study ...5 placebo) had a combination of clinical (myoclonus and/or absence seizures) and electroencephalogram findings that ... See full document

10

Management of postoperative nausea and vomiting: focus on palonosetron

Management of postoperative nausea and vomiting: focus on palonosetron

... despite recent issues relating to a ‘Black Box’ regulatory warning from the US Federal Drug Administration (FDA) in relation to possible cardiac conduction delay. It is cheap, has an NNT of 5 for both nausea and vomiting ... See full document

14

Scopolamine augmentation of a newly initiated escitalopram treatment for major depressive disorder: study protocol for a randomized controlled trial

Scopolamine augmentation of a newly initiated escitalopram treatment for major depressive disorder: study protocol for a randomized controlled trial

... Major depressive disorder (MDD) is a prevalent and dis- abling condition with a high frequency of non-recovery and recurrence, leading to substantial mortality and morbidity ...clinical ... See full document

7

Functional impairment in patients with major depressive disorder: the 2-year PERFORM study

Functional impairment in patients with major depressive disorder: the 2-year PERFORM study

... in depressive symptoms and functional impairment was seen imme- diately following initiation or switch of antidepressant monotherapy, followed by more gradual improvement and long-term stabilization; improvement ... See full document

11

Desvenlafaxine in the treatment of major depressive disorder

Desvenlafaxine in the treatment of major depressive disorder

... Abstract: Major depressive disorder (MDD) is among the most incapacitating conditions in the ...isolated major active metabolite of venlafaxine, O-desmethylvenlafaxine: it is the third SNRI to ... See full document

10

Meta-analysis of the Efficacy and Safety of Adjunctive Rosuvastatin for Dyslipidemia in Patients with Schizophrenia

Meta-analysis of the Efficacy and Safety of Adjunctive Rosuvastatin for Dyslipidemia in Patients with Schizophrenia

... random number table), while selective reporting and other sources of bias were rated as having unclear risk in all RCTs (Supplemental Figure 1). In 3 RCTs, the weighted mean Jadad scores were 3.4 (range=2-5, Table 1). ... See full document

8

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