antisense primer for reverse transcription. See below for explana- tion) were confirmed as true fusion transcripts in the 45 leukemia samples, of which 30 fusions were in the 29

Whole- exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype. Blood

AHN, associated hematological neoplasm; AML, acute myeloid leukemia; BM, bone marrow; CM, cytomorphology; FCM, flow cytometry; MC, mast cells; MCL, mast cell leukemia; MCL-AHN, mast

Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: indepen- dent favorable prognostic factor within NPM1 mutated patients. CEB- PA single mutation can be

Port, M., et al., Prognostic significance of FLT3 internal tandem duplication, nucleophosmin 1, and CEBPA gene mutations for acute myeloid leukemia patients with normal karyotype and

Abbreviations: APL, Acute promyelocytic leukemia; ATRA, all- trans-retinoic acid; CBF-AML, core binding factor acute myeloid leukemia; CN-AML, normal cytogenetics-acute

Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome. Bakshi SR,

Detection of NPM1 exon 12 mutations and FLT3 – internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia.. Angela YC Tan 1

Adverse prognostic effect of homozygous TET2 mutation on the relapse risk of acute myeloid leukemia in patients of normal karyotype. Potential application of IDH1 and

AML: acute myeloid leukemia; LSC: leukemia stem cell; CN-AML: cytogenetic normal acute myeloid leukemia; NSCLC: non-small cell lung cancer; TCGA : The Cancer Genome Atlas;

childhood Acute Myeloid Leukemia; sAML, secondary Acute Myeloid Leukemia; AML, Acute Myeloid Leukemia; t-MN, therapy-related Myeloid Neoplasms; MPN, Myeloproliferative

Panoramic view of common fusion genes in a large cohort of Chinese de novo acute myeloid leukemia patients. Analysis of 36 fusion genes in 595 cases of de novo pediatric

However, our present study could not demonstrate a signif- icant effect of DNMT3A mutations on both clinical features and prognosis, regardless of mutation type

Gaidzik et al., “IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid Leukemia and confer adverse prognosis in cytogenetically normal acute myeloid Leukemia

Ph: Philadelphia chromosome; CML: chronic myeloid leukemia; ALL: acute lymphoblastic leukemia; AML: acute myeloid leukemia; MPAL: mixed‑pheno‑ type acute leukemia; TK: tyrosine

Electropherogram showing the fusion transcripts involving ETV6 and the catalytically active NTRK3 isoform (3a) and ETV6 fused to the truncated NTRK3 isoform (3b).. In either

ACC: Adenoid cystic carcinoma; ALL: Acute lymphoblastic leukemia; AML: Acute myeloid leukemia; APL: Acute promyelocytic leukemia, cholangio cholangiocarcinoma; CML: Chronic

AML: Acute Myeloid Leukemia; CN-AML: Cytogenetically normal AML; APL: Acute Promyelocytic Leukemia; FAB: French-American-British system; GEP: Gene expression profiling;