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[PDF] Top 20 Glomerular Complement Components in Human Glomerulonephritis

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Glomerular Complement Components in Human Glomerulonephritis

Glomerular Complement Components in Human Glomerulonephritis

... 21 patients had granular C3 deposits without detectable Ig. C5, C6, and C8 were present in the majority of these patients while C1q was absent and scant C4 was observed in only two patients. The presence of only ... See full document

9

Properdin and C3 Proactivator: Alternate Pathway Components in Human Glomerulonephritis

Properdin and C3 Proactivator: Alternate Pathway Components in Human Glomerulonephritis

... of human glomerulonephritis have suggested that alternate pathways of activation of the third component of complement may be important in some forms of ...membranoproliferative ... See full document

12

Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells

Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells

... which complement membrane attack complexes (MAC) that are deposited in the glomerular mesangium might be pathogenic, we stimulated rat glomerular mesangial cells grown in vitro with nascent MACs ... See full document

7

Renal cell–expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis

Renal cell–expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis

... to glomerular endothelial ...primary glomerular damage and the site of secondary inter- stitial nephritis that accompanies the glomerular ...reported glomerular expression of TNFR2 in ... See full document

12

SP 40,40, a newly identified normal human serum protein found in the SC5b 9 complex of complement and in the immune deposits in glomerulonephritis

SP 40,40, a newly identified normal human serum protein found in the SC5b 9 complex of complement and in the immune deposits in glomerulonephritis

... with glomerulonephritis but is not found in normal ...terminal complement components and its physicochemical properties are similar to, but distinct from, those of the S protein of ...of ... See full document

8

Glomerulonephritis mediated by antibody to glomerular basement membrane  Immunological, clinical, and histopathological characteristics

Glomerulonephritis mediated by antibody to glomerular basement membrane Immunological, clinical, and histopathological characteristics

... hemagglutination (31 of 32). Although sera were not tested from six patients, circulating antibodies were demonstrated by some test in 36 of 39 of the remainder. Histologically, half of the patients had minor and ... See full document

12

Partial characterization of antigenic streptococcal plasma membrane components in acute glomerulonephritis

Partial characterization of antigenic streptococcal plasma membrane components in acute glomerulonephritis

... poststreptococcal glomerulonephritis stained parts of the glomerular basement membrane and mesangium of kidney tissue obtained from the same patients during the early phase of the ... See full document

8

Abrogation of Macrophage dependent Injury in Experimental Glomerulonephritis in the Rabbit: USE OF AN ANTIMACROPHAGE SERUM

Abrogation of Macrophage dependent Injury in Experimental Glomerulonephritis in the Rabbit: USE OF AN ANTIMACROPHAGE SERUM

... of glomerular cell culture and morphologic techniques to be present in large numbers within the glomeruli of rabbits with acute serum sickness (AcSS) and in a passive model of the autologous phase of ... See full document

14

Macrophage induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit

Macrophage induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit

... in glomerulonephritis. The mechanisms of glomerular fibrin deposition are ...measuring glomerular fibrin deposition and glomerular procoagulant activity in a passive model of the autologous ... See full document

9

Relationship of Serum Complement Levels to Events of the Malarial Paroxysm

Relationship of Serum Complement Levels to Events of the Malarial Paroxysm

... Malarial paroxysms due to Plasmodium vivax were studied for alterations in whole serum complement (C¢) and certain C¢ components. The objective was to relate C¢ values with events of the parasite cycle ... See full document

11

Immunofluorescent localization of immunoglobulins, complement, and fibrinogen in human diseases  II  Acute, subacute, and chronic glomerulonephritis

Immunofluorescent localization of immunoglobulins, complement, and fibrinogen in human diseases II Acute, subacute, and chronic glomerulonephritis

... In acute glomerulonephritis small amounts of fibrinogen are present in a patchy distribution in renal glomeruli, in contrast to subacute and chronic glomerulonephritis, in which primaril[r] ... See full document

8

Spectrum of Biopsy Proven Renal Diseases in the Paediatric Age Group between 1997-2006 from a Tertiary Center of India.

Spectrum of Biopsy Proven Renal Diseases in the Paediatric Age Group between 1997-2006 from a Tertiary Center of India.

... Isolated glomerular hematuria – In patients with asymptomatic microscopic hematuria (ie, persistent microscopic hematuria with dysmorphic red blood cells, negative "dipstick" for proteinuria, normal serum ... See full document

92

Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin dependent kinase antagonist

Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin dependent kinase antagonist

... Roscovitine does not affect other variables that alter glomer- ulonephritis. Because previous studies showed that the Thy1 antibody binds to the mesangial cell within 1 h (13), in this study we elected to first ... See full document

10

Clinicopathological analysis of proliferative glomerulonephritis with monoclonal IgG deposits in 5 renal allografts

Clinicopathological analysis of proliferative glomerulonephritis with monoclonal IgG deposits in 5 renal allografts

... fixes complement, causing endo- thelial injury and ensuing endocapillary and mesangial prolif- eration [1 – ...serum complement levels were normal in our series in most patients, as is often the case re- ... See full document

7

Case Report Fibrillary glomerulonephritis with anti-glomerular basement membrane antibody: a combined glomerular insult

Case Report Fibrillary glomerulonephritis with anti-glomerular basement membrane antibody: a combined glomerular insult

... progressive glomerulonephritis (RPGN) is a clinical syndrome characterized by quick and propagative deterioration of renal function with loosing 50% or more of renal function within three ...fibrillary ... See full document

8

Excretion of complement proteins and its activation marker C5b-9 in IgA nephropathy in relation to renal function

Excretion of complement proteins and its activation marker C5b-9 in IgA nephropathy in relation to renal function

... In other renal diseases, strong associations of urinary fH and MAC levels with disease progression have been demonstrated (15-17). Recently, Zang et al. proposed that urinary fH in patients with IgAN may be a useful ... See full document

8

AUTOANTIBODIES IN HUMAN GLOMERULONEPHRITIS

AUTOANTIBODIES IN HUMAN GLOMERULONEPHRITIS

... In 23 cases of glomerulonephritis of all stages antibodies to human renal tissue were demonstrated in 75% of the 122 tests done average titre 1: 623 and 18, or 78.3% of the cases were po[r] ... See full document

7

COMPLEMENT AND ITS COMPONENTS IN HUMAN CEREBROSPINAL FLUID

COMPLEMENT AND ITS COMPONENTS IN HUMAN CEREBROSPINAL FLUID

... An indirect method of estimation of C' activity was therefore considered more appropriate, and the samples were also tested by addition of preferably several different volumes to an accu[r] ... See full document

5

Complement activation products in the circulation and urine of primary membranous nephropathy

Complement activation products in the circulation and urine of primary membranous nephropathy

... of complement and correlation with anti-PLA2R antibody ...The complement may be activated through lectin pathway in the patients with positive anti-PLA2R antibodies, and through alternative pathway in the ... See full document

13

Continuing C3 breakdown after bilateral nephrectomy in patients with membrano proliferative glomerulonephritis

Continuing C3 breakdown after bilateral nephrectomy in patients with membrano proliferative glomerulonephritis

... measured serially in two patients with membrano-proliferative glomerulonephritis who were subjected to bilateral nephrectomy and maintained by peritoneal dialysis for 2 wk before renal transplantation. In both ... See full document

8

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