[PDF] Top 20 Glutamine Transport in Rat Kidney Mitochondria in Metabolic Acidosis

... of glutamine deamidation (low temperature, p-chloromercuribenzoate, ...that glutamine crosses the inner membrane by a carrier-mediated step and that this step is rate-limiting in glutamine ... See full document

... Chronic metabolic acidosis (CMA) is associated with an adaptive increase in the bicarbonate absorptive capacity of the rat medullary thick ascending limb ...NHE-3 transport activity ( P , ... See full document

... by acidosis in the present study (Table 3), but its activity in the goldfish kidney was much higher than previously reported in the goldfish gill (Sinha et ...during acidosis would tend to inhibit ... See full document

... either acidosis or ...of glutamine by the acidotic kidney and 14% by the alkalotic kidney, it is apparent that renal energy sources change with acid-base state and that glutamine ... See full document

... renal metabolic response was studied in rats made acidotic by oral feeding of ammonium ...by kidney slices from rats during the first 6 hr of acidosis, but after 48 hr of ammonium chloride feeding, ... See full document

... Cardiac arrest characteristics, in-hospital management and outcome data were prospectively collected according to the Utstein style [8]. The following information was recorded prospectively for each patient: demographic ... See full document

... of acidosis per se. We prefer to adhere to the concept that acidosis can best be regarded as an excess of protons over those normally found in physiological states, caused either from the loss of base or ... See full document

... HCL-INDUCED METABOLIC AcIDosis When vasopressin was administered in association with a restricted water intake to four dogs with steadystate HCl-induced metabolic acidosis ingesting the [r] ... See full document

... concentrations of insulin-like growth factor-I, free thyroxine and tri-iodothyronine were significantly lower during acidosis. In conclusion, chronic metabolic acidosis causes negative nitrogen ... See full document

... acute metabolic acidosis enhances circulating PTH activity, and (b) PTH markedly contributes to the renal response against acute metabolic acidosis by enhancing urinary ... See full document

... mitochondrial transport systems for malate, a-oxoglutarate, and ...by rat liver mitochondria are demonstrated to be mediated by the influence of MMA on the transport ...the metabolic ... See full document

... When acetate-C14, a metabolic precursor of citrate, was administered, an increased incorporation of the C14 into urinary citrate was observed in alkalosis and a decreased incorporation i[r] ... See full document

... chronic metabolic acidosis in patients with chronic kidney disease develops after a drop of glomerular filtration rate to less than approximately 25 ... See full document

... Metabolic acidosis is associated with enhanced renal ammonia-genesis which is regulated, in part, by ...chronic metabolic acidosis on nitrogen utilization and muscle protein metabolism is ... See full document

... Studies of the BBB in vivo gave incomplete information because they did not take into account the fact that metabolites have to pass both the luminal and abluminal membranes to gain access to brain cells. To provide a ... See full document

... standard metabolic rate and the proton leakiness of mitochondrial ...electron transport chain activity and/or in ATP turnover of the cell, (iii) by changing the volume density of mitochondria inside ... See full document

... net transport period, one CCD was exposed to pH ...HCO transport studies. Two more cycles of low pH ex- posure and transport measurements were then ...net transport period, a second CCD was ... See full document

... as metabolic acidosis, anemia, inflamma- tion, hyperactivity of the Renin-Angiotensin-Aldosterone System (RAAS), vitamin D deficiency, physical inactivity, excess of fat mass as well as nitrogen catabolites ... See full document

... Several factors have been implicated in the effect of metabolic acidosis on the progression of kidney disease. These include ammonia-induced complement activation and increased production of ... See full document

... choline transport into mitochondria as a single step ...to rat kidney mitochondria was oxidized to betaine within the mitochondria ...load rat kidney ... See full document