[PDF] Top 20 Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon
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Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon
... distance from the ZLI (more than 10 cell diameters, close to the telencephalic boundary: two clones in one embryo, ...Hh signalling and subsequently acquire prethalamic or thalamic fate but cells that ... See full document
10
Patterning the zebrafish diencephalon by the conserved zinc finger protein Fezl
... the diencephalon are established. Although the embryonic diencephalon has been proposed to have a segmental organization (Figdor and Stern, 1993; Puelles and Rubenstein, 2003), cell-lineage restriction ... See full document
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Regulation of ventral midbrain patterning by Hedgehog signaling
... that, rather than being a single boundary, the MHB may be a compartment flanked by two boundaries, much like the zona limitans intrathalamica (ZLI) in the diencephalon (Kiecker and Lumsden, ... See full document
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brother of cdo (umleitung) is cell autonomously required for Hedgehog mediated ventral CNS patterning in the zebrafish
... the zona limitans interthalamica (ZLI) ...absent from the ZLI ...absent from the lateral floor plate (D ⬘ ...the diencephalon (arrowhead in E), ventral midbrain/hindbrain (bracket) and ... See full document
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Mechanisms of patterning and neurogenesis in the zebrafish forebrain
... in zebrafish (L) and mice ...d, diencephalon, e, eye, hy, hypothalamus, id, intermediate domain, op, olfactory placode, or, optic recess, os, optic stalk, t, telencephalon, te, tectum, zli, zona ... See full document
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Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates
... RNA from each plasmid was produced by in vitro transcription and a range of doses was injected into one-cell stage zebrafish ...prepared from non-deformed 24 hpf embryos injected with this dose was ... See full document
10
Dbx1b defines the dorsal habenular progenitor domain in the zebrafish epithalamus
... In zebrafish, the dorsal habenulae regulate fear and aversion ...the zebrafish habenulae also serve as an excellent model to study the basic mechanisms underlying the development of left-right brain ... See full document
9
dTcf antagonises Wingless signalling during the development and patterning of the wing in Drosophila
... signalling directly, we have probed the ability of this molecule to interfere with the Arm/dTcf mediated activation of specific targets Fig. 2. Effects of overexpression of dTcf under the control of ms1096G4 alone ... See full document
8
Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis
... stem from either apoptotic cells of adjacent tissues or adenohypophyseal cells with debris extruded from the ...cells from the ANR region after labeling at tailbud stage ... See full document
12
Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon
... In the Six3-null brain, early ectopic expansion of Wnt1 expression is not sufficient to block rostral diencephalic formation. However, at around the 17-somite stage, the abnormal anterior expansion of Wnt activity causes ... See full document
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Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons
... the zebrafish MZsmo mutant phenotype suggested a possible hypothesis for why mouse Shh and zebrafish MZsmo mutants have such different phenotypes ...in zebrafish (Huang and Schier, 2009; Karlstrom et ... See full document
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TCF4/beta-Catenin Complex Activates Smo and Gli1 to Promote Migration and Proliferation of Hepatocellular Carcinoma Cells
... Open reading frame regions of TCF4 (NM_013685.2, NCBI) and β-catenin (NM_001165902.1, NCBI) were synthesized from the Sangon corporation (Shanghai, China). The overexpression of TCF4 and β-catenin was via ... See full document
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Splitting the Hedgehog signal: sex and patterning in Drosophila
... obtained from the Developmental Studies Hybridoma Bank maintained by the University of Iowa, Department of Biological Sciences, Iowa City, IA ...Williams from the UAB imaging facility, and Kim Riddle at the ... See full document
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Signal dynamics in Sonic hedgehog tissue patterning
... for patterning tissue architecture are highly complex and are typically analyzed only at long times after secretion ...Sonic hedgehog (Shh), cooperate in modular fashion to regulate tissue patterning ... See full document
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Hepatic autophagy is differentially regulated in periportal and pericentral zones - a general mechanism relevant for other tissues?
... hepatoctyes from these transgenic mice again are suitable for measuring differences in transport of amino acids, particularly glutamine, in mTORC1 activity and other known relevant ... See full document
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The miR 30 microRNA family targets smoothened to regulate hedgehog signalling in zebrafish early muscle development
... the Hedgehog (Hh) pathway due to its importance in the induction and patterning of the vertebrate embryo [20] and its strong association with the development of many ...developing zebrafish embryo by ... See full document
9
Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube
... Int J De,' Bioi 39 809 816 (1995) 809 I I I I I I I I I I I I I I I I I I I Sonic hedgehog a common signal for ventral patterning along the rostrocaudal axis of the neural tube JOHAN ERICSON', JONAS M[.] ... See full document
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Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling
... The isobologram and combination index (CI) were calcu- lated according to the Chou and Talalay median effect principal [24] using Calcusyn software (Biosoft). The drugs were applied at a fixed ratio of the IC 50 across a ... See full document
11
PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly
... (A/P) patterning defects and recapitulates the brain malformations observed in ...A/P patterning and set the stage for the identification of new HPE candidate ... See full document
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Fgf signalling controls the dorsoventral patterning of the zebrafish embryo
... Fgf signalling does also affect the DV axis of the early zebrafish ...Fgf signalling does not cause the loss of mesoderm but a dorsal expansion of ventral mesodermal fates concomitant with a ... See full document
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