[PDF] Top 20 HEPATOPROTECTIVE POTENTIAL OF POLYHERBAL PREPARATION AGAINST CCl4 INDUCED LIVER TOXICITY IN RATS

... of Polyherbal preparation indicating restoration of hepatic cell ...The Polyherbal preparation significantly (P<0.05) reduced the liver enzymes levels in experimental animals shows ... See full document

... the hepatoprotective potential of Enhydra fluctuans ...(Compositae) against carbon tetrachloride-induced oxidative damage in ...The hepatoprotective effect of ethyl acetate fraction of ... See full document

... environment. Liver injury induced by various hepatotoxins has been recognized as a major toxicological problem for ...tract, liver is an important target of toxicity to xenobiotics, oxidative ... See full document

... The rats were then sacrificed by cervical dislocation and the liver was dissected, cleaned of extraneous tissue, washed by ice cold saline, blotted with filter paper and weighed ...immediately. Liver ... See full document

... acute liver failure in many western countries 29 ...the liver and kidneys, paracetamol overdose causes potentially fatal conditions known as acetaminophen-induced hepatotoxicity and ... See full document

... evaluated against biochemical and histopathological changes, induced by carbon tetrachloride in male wistar albino ...known hepatoprotective drug was used as positive control. Liver damage was ... See full document

... on liver damage induced by CCl4 and the toxic effects of the similar doses in ...the liver caused by CCl4 was evident by the alteration in serum marker enzymes concentration beside the ... See full document

... in liver disorder. The aim of present work is to study the hepatoprotective effect of methanolic extract of whole plant of Leucas cephalotes against carbontetrachloride induced liver ... See full document

... a liver tonic ...the hepatoprotective activity and anti oxidant activity an effort has been made to evaluate the hepatoprotective activity and anti oxidant activity of Plectranthus amboinicus ... See full document

... The plant materials were shade dried for 7 days and coarsely powdered. The powder was mixed thoroughly with 6 times the volum e of DMSO in water and stirred continuously until the volume reduced to 1/3rd. The extract was ... See full document

... in liver cell results in loss of membrane integrity and ...the toxicity of carbon tetrachloride due to increased production of toxic reactive metabolites such as trichloro-methyl radical by the microsomal ... See full document

... combination induced a low activity of hepatic enzymes as compared to others combinations presented by Zn 25 curve below from the others graphs (Figure 3A and ...addition, liver is protected by association ... See full document

... the rats from each group were collected by tail bleeding for baseline biochemical test to know the state of the animals’ liver before the inducement of the ...Wistar rats were induced with CCl ... See full document

... Nitric oxide is a small molecule that contains one un- paired electron. It is generated in biological systems by NADPH-dependent nitric oxide synthases. It acts as an important oxidative biological signaling molecule in ... See full document

... Sixty Wistar rats of either sexes (30 male and 30 female) were procured from Raj Biotech (India) Ltd., Pune, India. The animals were housed in standard rat cages and were fed with commercially available rat feed ... See full document

... of liver. The efficacy of any hepatoprotective drug is dependent on its capacity of either reducing the harmful effect or maintaining the normal hepatic physiology, which has been disturbed by a ... See full document

... and liver was lesser in Group II animals, when compared with normal control, and it attained an almost normal value in group III ...as liver recorded significant increment in CCl 4 - administered ... See full document

... Carbon tetrachloride is one of the most commonly used hepatotoxin. It is well documented that carbontetrachloride is biotransformed under the action of cytochrome P-450 in the microsomal compartment of liver to ... See full document

... the liver in the normal control group (Group I) showed no degeneration, necrosis, or ...the liver exhibited severe degeneration of hepatic microstructure along with bridging fibrosis and necrosis of ... See full document

... At the end of the experiment, the overnight fasted animals (the control and experimental animals) were sacrificed under light ether anesthesia. Blood samples were collected by cardiac puncture before incision of the ... See full document