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[PDF] Top 20 High pH prevents retinoic acid induced teratogenesis

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High pH prevents retinoic acid induced teratogenesis

High pH prevents retinoic acid induced teratogenesis

... Int J Dn lIiol 39 409 414 (1995) 409 Original Article High pH prevents retinoic acid induced teratogenesis ROBBERT CRETaN' GIDEON ZWAAN and RENE DOHMEN Department of Experimental Zoology, University o[.] ... See full document

6

Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

... + high-dose melatonin (Mlt-H), and RA + alendronate sodium (positive ...Tartrate-resistant acid phosphatase (TRACP) ...effects induced by RA, increasing the amount of trabecular bone in OP mice, ... See full document

14

Polyomavirus Small t Antigen Prevents Retinoic Acid-Induced Retinoblastoma Protein Hypophosphorylation and Redirects Retinoic Acid-Induced G0 Arrest and  Differentiation to Apoptosis

Polyomavirus Small t Antigen Prevents Retinoic Acid-Induced Retinoblastoma Protein Hypophosphorylation and Redirects Retinoic Acid-Induced G0 Arrest and Differentiation to Apoptosis

... fixed in 1 ml of 90% methanol at ⫺20°C. The cells were stored at ⫺20°C until analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS- PAGE). Cells were solubilized in 50 ␮l of loading buffer (6% SDS, 4 ... See full document

13

Co-administration of retinoic acid and atorvastatin mitigates high-fat diet induced renal damage in rats

Co-administration of retinoic acid and atorvastatin mitigates high-fat diet induced renal damage in rats

... Biochemical analyses. At the end of the study, the animals were fasted for 12 hr. Afterwards, blood sample was collected for the measurement of BUN, creatinine and serum lipid profile. Serum BUN and creatinine were ... See full document

6

Distinct Roles of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factors in Inflammatory Response and Cancer

Distinct Roles of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factors in Inflammatory Response and Cancer

... vIRF1 and p53. vIRF1 function is not limited to the antiviral re- sponse. It also inhibits the function of p53 and modulates apop- totic signaling (Fig. 3). p53 is a transcription factor which re- sponds to stress ... See full document

13

Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head

Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head

... In this study, we established a SONFH rat model using prednisolone acetate. The effects of miR- 140-5p expression inhibition and/or ATRA treatment on the adipogenic differentiation of MSCs were then observed. We ... See full document

9

Disto proximal regional determination and intercalary regeneration in planarians, revealed by retinoic acid induced disruption of regeneration

Disto proximal regional determination and intercalary regeneration in planarians, revealed by retinoic acid induced disruption of regeneration

... extremely high compared with usual morphogen ...the high concentration of RA needed may be due to the hypothetical receptors present in planarians, as retinoid receptors found in other invertebrates (RXR; ... See full document

5

Retinoic acid inhibits the regulated expression of vascular cell adhesion molecule 1 by cultured dermal microvascular endothelial cells

Retinoic acid inhibits the regulated expression of vascular cell adhesion molecule 1 by cultured dermal microvascular endothelial cells

... Our observations suggest that the transcriptional inhibition of the VCAM-1 promoter by t-RA is mediated in part by its effects on activation of a specific NF-kB–dependent complex formation. NF-kB transcription factors ... See full document

10

Nuclear hormone receptors in podocytes

Nuclear hormone receptors in podocytes

... The mechanisms by which aldosterone induces pro- teinuria are likely complex. However, the observation that podocytes express MR suggests a direct role of liganded MR in podocyte injury. In podocytes, aldoster- one ... See full document

14

All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis

All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis

... At the end of the experiment, the rabbits fasted for 12 h prior to anesthesia and peripheral blood samples were obtained from the marginal vein of their ear. Then, se- rum samples were separated and analyzed for total ... See full document

6

A phosphorylation defective retinoic acid receptor mutant mimics the effects of retinoic acid on EGFR mediated AP-1 expression and cancer cell proliferation

A phosphorylation defective retinoic acid receptor mutant mimics the effects of retinoic acid on EGFR mediated AP-1 expression and cancer cell proliferation

... SCC4 and SCC25 cells were treated with 1 m M all trans RA for 16 hours. To determine if ERK1 or p38 MAPKs phos- phorylated RAR a , some cultures were treated with 50 m M PD98059 or 10 mM SB203580 for the same time ... See full document

9

Identification of influential proteins in the classical retinoic acid signaling pathway

Identification of influential proteins in the classical retinoic acid signaling pathway

... The liganded heterodimer can initiate the transcrip- tion of target genes after binding to a DNA response element. However, there may be other intermediate transcription factors or nonclassical pathways that can ... See full document

16

Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury

Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury

... damage. Retinoic acid (RA) has a neuroprotective effect in both ischemic brain injury and SCI, however the relationship between BSCB disruption and RA in SCI is still ... See full document

13

Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids

Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids

... cellular retinoic acid-binding proteins (CRABPs) may regulate the accessibility of retinoic acid (RA) to the RA receptors and are thought to affect the prognosis of ...fatty ... See full document

10

Cyclic AMP is a hepatorenal link influencing natriuresis and contributing to glucagon induced hyperfiltration in rats

Cyclic AMP is a hepatorenal link influencing natriuresis and contributing to glucagon induced hyperfiltration in rats

... depend on a prior action of this hormone on the liver resulting in the liberation of a mediator and/or of a compound derived from amino acid metabolism. This study investigates in anesthetized rats the possible ... See full document

9

<p>A rare case of acute promyelocytic leukemia with IRF2BP2-RARA fusion; and literature review</p>

<p>A rare case of acute promyelocytic leukemia with IRF2BP2-RARA fusion; and literature review</p>

... Arsenic binds to the PML moiety of the PML-RARA fusion. ATRA binds to the RARA portion. Each drug initiates biochemically independent degradation pathways, 12 which might partially explain the lack of response of APL ... See full document

7

Characterization of cDNAs encoding two chick retinoic acid receptor alpha isoforms and distribution of retinoic acid receptor alpha, beta and gamma transcripts during chick skin development

Characterization of cDNAs encoding two chick retinoic acid receptor alpha isoforms and distribution of retinoic acid receptor alpha, beta and gamma transcripts during chick skin development

... Int J De, BioI 39 587 596 (1995) Original Article Characterization of cDNAs encoding two chick retinoic acid receptor a isoforms and distribution of retinoic acid receptor a, Band y transcripts during[.] ... See full document

10

Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells

Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells

... To investigate the role of DAGL in neuronal differentiation, Neuro-2a cells were incubated with RA, which induced a time-dependent outgrowth of neurites (Figures 2A,B). This resulted in increased 2-AG net levels ... See full document

13

Stage dependent responses of the developing lung to retinoic acid signaling

Stage dependent responses of the developing lung to retinoic acid signaling

... inhibition induced by RA treatment is correlated with ectopic expression of RAR β in distal buds, whereas the increase in distal bud number caused by a block in RA signaling is correlated with a decrease of RAR β ... See full document

6

Polycomb recruitment attenuates retinoic acid induced transcription of the bivalent NR2F1 gene

Polycomb recruitment attenuates retinoic acid induced transcription of the bivalent NR2F1 gene

... to the upstream transcription start site (P1-TSS). The nucleotide sequence of the 441 to 382 region, which is required for a potent RA induction (>2-fold), is shown at the bottom of the figure. Note that in the bar ... See full document

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