[PDF] Top 20 Host-Mediated Repair of Discontinuities in DNA From T4 Bacteriophage
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Host-Mediated Repair of Discontinuities in DNA From T4 Bacteriophage
... KOZINSKI of Human Genetics, University of Pennsylvania School of Medicine, Philadelphia, Department Pennsylvania 19104 Discontinuities of T4 DNA which are caused by excision of UV-damage[r] ... See full document
10
Repair of Topoisomerase-Mediated DNA Damage in Bacteriophage T4
... m-AMSA-induced repair product ...with T4 origin ori(34)] or pAC1000 and pBS5 (lanes 3–4 and 7–8; without origin) were infected with T4 strain K10, and m-AMSA was added where indicated 6 min after ... See full document
10
Host- and Phage-Mediated Repair of Radiation Damage in Bacteriophage T4
... Escherichia coli str-ains Desi-nation Genotype with respect to repair B Wild B.,-, H/r30R uCvr-e vr-e H s30R uvrA res* R15 N1071 N1072 N1 252 Source Wild UV", X-ray sensitive Radioresist[r] ... See full document
11
Role of Gene 52 in Bacteriophage T4 DNA Synthesis
... Since it has been proposed that a nucleolytic activity is involved in initiation of T4 DNA synthesis 11, 12, 17, 35 and since there is some previous evidence for parental strand nicking [r] ... See full document
10
Requirement of a Functional Gene 32 Product of Bacteriophage T4 in UV Repair
... By examining the effect of UV irradiation on intracellular phage DNA by alkaline and neutral sucrose gradient sedimentation, we are able to demonstrate that gene 32 protein is essential [r] ... See full document
8
Role of the host cell in bacteriophage T4 development. II. Characterization of host mutants that have pleiotropic effects on T4 growth.
... Alternatively, the immediate cessation of phage production after late temperature shift-up of T4+-infected HDF cells suggests that Rho function is required throughout infection and raise[r] ... See full document
15
Bacteriophage T4-induced shut-off of host-specific translation.
... Since RIF blocks RNA polymerase in both infected and uninfected cells 10, 33, this experiment shows that the T4-induced restriction of host translation is not dependent on phage de novo [r] ... See full document
9
Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives
... for DNA binding ...DnaC from Aquifex aeolicus (pdb 3ec2) ...branched DNA substrate which suggests a possible mode of cooperative interaction with 32 ssb protein (Figure 5C) ...with DNA, or ... See full document
17
Synthesis of T4 DNA and bacteriophage in the absence of dCMP hydroxymethylase.
... At least for HMase, this was true even using temperature-sensitive mutants under conditions where pools of replicating DNA were present 15; if DNA synthesis was then allowed to start in [r] ... See full document
8
Early intermediates in bacteriophage T4 DNA replication and recombination.
... ii After multiple infection, recombinational intermediates containing label from both parents first appeared as early as 1 min after the onset of replication, long before all parental DN[r] ... See full document
19
PROPERTIES OF BACTERIOPHAGE T4 MUTANTS DEFECTIVE IN DNA POLYMERASE
... Burst size determinations: Burst sizes produced by amber mutants were measured by (nearly completely) adsorbing a n average of about 0.1 particle per BB cell (nonpermissive con[r] ... See full document
14
Rates of spontaneous mutation in bacteriophage T4 are independent of host fidelity determinants.
... We screened the following host mutator mutations for effects on spontaneous mutation rates in T4: mutT (destruction of aberrant dGTPs), poZA, polB and polC (DNA polymerases), d [r] ... See full document
12
BACTERIOPHAGE T4 GENE 32 PARTICIPATES IN EXCISION REPAIR AS WELL AS RECOMBINATIONAL REPAIR OF UV DAMAGES
... Specifi- cally, defects in pairing of complementary DNA strands (of different paren- tage) across UV damages would reduce potential repair of damaged DNA by recomb[r] ... See full document
13
A MAJOR ROLE FOR BACTERIOPHAGE T4 DNA POLYMERASE IN FRAMESHIFT MUTAGENESIS
... The spectra of frameshift mutations produced by the mutator polymerases tsL56, tsL98 and, tsL88 are consistent with differences in their effects on frameshift mutation[r] ... See full document
14
Inactivation of Bacteriophage T4 by Ethyl Methanesulfonate: Influence of Host and Viral Genotypes
... These strains included mutants exhibiting increased sensitivity to UV irradiation v, x, y, and combinations thereof; mutants defective in DNA synthesis ts mutations in DNA polymerase gen[r] ... See full document
8
UV irradiation impairs in vivo encapsidation of bacteriophage T4 DNA.
... This kinetic pattern of continued slow packaging in UV-irradiated infections is consistent with a transient packaging block which diminishes the rate of encapsidation and thus differs fr[r] ... See full document
8
EXPRESSION OF THE rII FUNCTION BY NATIVE TRANSFORMING DNA OF BACTERIOPHAGE T4
... POL, VELDHUISEN and COHEN 1961), involving recombination of T4 transform- ing DNA with the genome of a helper phage in Escherichia coli B spheroplasts, offers a unique advant[r] ... See full document
9
Characterization of a bacteriophage T4 mutant lacking DNA-dependent ATPase.
... Increase in spontaneous mutation rate for T4 strains deficient in DNA-dependent ATPasea Mutation index frequency x 104 Strain Exptl Expt2 55 19 34 7.6 L148 dda T4D a Spontaneous mutation[r] ... See full document
5
Continued Synthesis of Bacterial DNA After Infection by Bacteriophage T4
... degree in 847 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Early in infection by bacteriophage T4, before replication has commenced, one detect the presence of newly[r] ... See full document
11
Bacteriophage T4-Directed DNA Synthesis in Toluene-Treated Cells
... Temperature-sensitive mutants in Some synthesis at early times after infection genes 32 which codes for a DNA-unwinding was observed in our in vitro system with an protein [1], 41, and 4[r] ... See full document
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