[PDF] Top 20 <p>HOXD9 Activates the TGF-β/Smad Signaling Pathway to Promote Gastric Cancer</p>
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<p>HOXD9 Activates the TGF-β/Smad Signaling Pathway to Promote Gastric Cancer</p>
... Cells were lysed using the RIPA buffer (Beyotime, Shanghai, China) and protein was extracted. Protein con- centration was determined using the BCA protein detec- tion kit (Beyotime). Tissue specimens were fi rst suf fi ... See full document
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SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis
... in cancer devel- opment and ...in gastric cancer, and its upregulation is associated with lymph node metastasis and poor ...in gastric cancer metastasis and the underlying mechanism ... See full document
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<p>G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer</p>
... lung cancer, miR-193A has been shown to promote metastasis of tumor cells by down-regulating G3BP1 ...and activates the 5 ′ untranslated region of G3BP1 mRNA, thereby controlling G3BP1 ... See full document
8
<p>Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition</p>
... The TGF- β 1/Smad signaling pathway is involved in many diseases, including cardiovascular diseases, neurologi- cal disorders and ...igenesis, TGF- β 1 acts as a tumour suppressor and ... See full document
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<p>miR-133b Suppresses Invasion and Migration of Gastric Cancer Cells via the COL1A1/TGF-β Axis</p>
... GSEA pathway enrichment analysis and found that COL1A1 was significantly enriched in TGF-β signaling ...pathway. TGF-β can be used as a sup- pressor or an activator in ...growth, ... See full document
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<p><em>Helicobacter pylori</em> upregulates TRPC6 via Wnt/β-catenin signaling to promote gastric cancer migration and invasion</p>
... pylori activates various intracellular ...and cancer development, 37,38 and is also responsible for ...-catenin signaling and induced the transcription of TRPC6 in GC ... See full document
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<p>12-Lipoxygenase promotes epithelial–mesenchymal transition via the Wnt/β-catenin signaling pathway in gastric cancer cells</p>
... Many signaling pathways and molecules including TGF- β , tumor necrosis factor- α , Wnt, Notch and sonic hedgehog (Shh) are implicated in the induction of ...ing pathway plays a critical role in ... See full document
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The Importance of Controlling the TGF-β Signaling Pathway in the Gastric Cancer Microenvironment
... cover TGF-β signal transduction [14-17]. Briefly, the TGF-β superfamily comprises more than 30 different members, including the TGF-βs (comprising the three highly homologous isoforms TGF-β1, ... See full document
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<p>Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway</p>
... liver cancer, oral cancer, breast cancer and pancreatic cancer through different ...B signaling pathway can induce the develop- ment of EMT and promote the invasion and ... See full document
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<p>Nucleolar and Spindle Associated Protein 1 (NUSAP1) Promotes Bladder Cancer Progression Through the TGF-β Signaling Pathway</p>
... the TGF- β signaling pathway is involved in the NUSAP1-regulated epithelial-mesenchymal transition in ...TGFBR1, p-Smad2/3, vimentin, and N-cadherin but an increase in E-cadherin; how- ever, ... See full document
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<p>MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition via TGFβ1/Smad2 signaling pathway in human bladder cancer</p>
... the TGF- β signaling pathway can promote cancer development and progression by increasing cancer cells motility, invasive- ness and metastasis, and inducing ... See full document
9
<p>Exosomes derived from HCC cells with different invasion characteristics mediated EMT through TGF-β/Smad signaling pathway</p>
... in cancer cells were analyzed by trans- mission electron microscopy (TEM), wound-healing assay, Trans-well invasion assay and Western blot-based assays, ...can promote the migration and invasion of ... See full document
9
<p>LncRNA TP73-AS1 Activates TGF-β1 to Promote the Migration and Invasion of Colorectal Cancer Cell</p>
... β signaling is a critical player in cancer ...of TGF- β in regulating the proliferation of cancer cells is contradictory in differ- ent types of cancer, it is generally believed that ... See full document
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<p>Involvement of TGF-β and ROS in G1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Under UVA Irradiation in a 3D Spheroid Model</p>
... increases TGF- β 1 in both in vivo and in vitro ...g/mL TGF- β 1 in the present study. Similar observations that TGF- β 1 causes cell growth arrest in the G1 phase by means of regulating the ... See full document
14
<p>Circ-OXCT1 Suppresses Gastric Cancer EMT and Metastasis by Attenuating TGF-β Pathway Through the Circ-OXCT1/miR-136/SMAD4 Axis</p>
... /Smad pathway is a latent initiator of EMT, a process ends in tumor invasion and ...the SMAD-binding element, initiating gene ...suppressed TGF- β /Smad-induced EMT through sponging ... See full document
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<p>TGF-β1 mediates lncRNA GAPLINC expression to promote the migration and invasion of non-small cell lung cancer</p>
... Data were presented as the mean values, based on three biological replicates of each experiment. Differences between NSCLC and non-cancer tissues were analyzed by paired t-test. Differences among cell transfection ... See full document
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<p>Overexpression Of ERβ Participates In The Progression Of Liver Cancer Via Inhibiting The Notch Signaling Pathway</p>
... Notch signaling pathway in the regulation of proliferation and apoptosis in liver cancer ...Notch signaling pathway in liver ... See full document
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MicroRNA involvement in mechanism of endogenous protection induced by fastigial nucleus stimulation based on deep sequencing and bioinformatics
... Microarray data of miRNAs after FNS treatment in ischemic rat cortex revealed significant changes in several miRNAs. The differential expression profile of miRNAs provides a hint of their potential functions during ... See full document
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<p>The inhibitory effect of oridonin on colon cancer was mediated by deactivation of TGF-β1/Smads-PAI-1 signaling pathway in vitro and vivo</p>
... a Smad binding element (SBE) on the PA-1 pro- moter, and triggers the degradation of the extracellular matrix, which in turn facilitates cell invasion and ...in TGF- β 1-treated LOVO cells, and inhibited ... See full document
10
Effect of canonical NF-κB signaling pathway on the differentiation of rat dental epithelial stem cells
... The cultured DESCs were lysed using radioimmunopreci- pitation buffer, and total protein was obtained by centrifu- ging at 12,000 rpm for 15 min at 4 °C. Then, we used BCA Protein Assay kit (Pierce Biotechnology, ... See full document
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