[PDF] Top 20 Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells
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Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells
... transmigration through primary genital epithelial ...(Fig. 1), participate in HIV-1 attachment to the genital epithelial ...remove cell surface heparan or ... See full document
11
Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication
... during cell-to-cell trans- fer? A significant number of virions are able to enter the target cell during transmission through the VS ...during cell- to-cell spread (for a review, ... See full document
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Molecular Interactions of Human Immunodeficiency Virus Type 1 with Primary Human Oral Keratinocytes
... control cell proliferation, differentiation, and survival (73, ...the cell type and the presence of other proapoptotic or antiapop- totic stimuli (21, 30), can either inhibit or promote ...manifested ... See full document
14
Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding
... of virus and cells does not overcome the diffusion-imposed limitations to infection that are operative at ambient gravity ...of cells in suspension are, like the mean viral displacement distance at ... See full document
7
Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes.
... The human immunodeficiency virus type 1-specific Vpu protein is a small integral membrane phosphopro- tein that induces degradation of the virus receptor CD4 in the endoplasmic ... See full document
13
Effects of Genital Tract Inflammation on Human Immunodeficiency Virus Type 1 V3 Populations in Blood and Semen
... the cell-free fractions of blood and semen samples from the first clinic visit were analyzed using V3-HTA, and the patterns were scored for the presence of multiple bands, with each band representing a ... See full document
7
Infection of SK-N-MC cells, a CD4-negative neuroblastoma cell line, with primary human immunodeficiency virus type 1 isolates.
... whether primary human immunodeficiency virus type 1 isolates could infect CD4- negative cells, we obtained a panel of 23 clinical isolates and characterized the early ... See full document
5
Herpes simplex virus type 2 infection triggers AP 1 transcription activity through TLR4 signaling in genital epithelial cells
... of cell mem- brane for sensing extracellular stimuli, such as bacteria ...U937 cells (human leukemic monocyte lymphoma cell line) and HEC-1-A cells, and examined the TLR4 ... See full document
14
Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system.
... replicating virus is consistent with the low-frequency usage of most secondary initiation sites in the cell-free system (,10% of the PPTs ...the cell-free system, this is a preferred ... See full document
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Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells
... the epithelial receptor for MeV particle-based infections (6, 8, ...myeloid cells to HAE requires nectin-4, we took advantage of a viral mutant with the capacity to use SLAMF1 as a cellular receptor but not ... See full document
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Dynamic Host Energetics and Cytoskeletal Proteomes in Human Immunodeficiency Virus Type 1-Infected Human Primary CD4 Cells: Analysis by Multiplexed Label-Free Mass Spectrometry
... and cell survival were also noted in complementary high-throughput ...CD4 cells would be in line with the prelude to apoptosis seemingly evident in our present study at 24 h ...uninfected cells, ... See full document
13
Cell Cycle- and Vpr-Mediated Regulation of Human Immunodeficiency Virus Type 1 Expression in Primary and Transformed T-Cell Lines
... EDTA, 1% fetal bovine serum). The concentrated cells were passed slowly through an 18-gauge needle three times prior to loading to ensure single-cell ...separation. Cells were separated ... See full document
9
Cell type-specific fusion cofactors determine human immunodeficiency virus type 1 tropism for T-cell lines versus primary macrophages.
... Table 1 shows that high concentrations of MAb A3D8 (reported to block infection by macrophage-tropic iso- lates [45]) had no inhibitory effects on fusion mediated by the Ba-L Env (or the LAV Env) when tested ... See full document
9
Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1.
... CD4 1 T-cell depletion remains a key unexplained charac- teristic of acquired immunodeficiency, which predisposes the patient to lethal infectious and neoplastic complications of AIDS and for which ... See full document
9
A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells.
... of human immunodeficiency virus type 1 (HIV-1) in human glioma H4/CD4 cells which stably express transfected CD4 DNA ...H4/CD4 cells with the N1T strain of ... See full document
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Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis in Human Neuronal Cells
... NT2 cells in a dose-dependent man- ner in both Vpr and gp120 treatments ...of 1 ng/ml, only a few labeled nuclei of neurons were detected with both of these proteins, as deter- mined by a comparison of the ... See full document
10
Antibody Binding and Neutralization of Primary and T-Cell Line-Adapted Isolates of Human Immunodeficiency Virus Type 1
... infected cells, except that 320SI env was isolated from an infectious molecularly cloned provirus, ...Cross) through the NIBSC AIDS Reagent Project (Herts, United ...the virus population and reca- ... See full document
12
Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection
... variable human leukocyte antigen class I (HLA-I) molecules ...T cells can exacerbate the losing battle for CTLs, leading to the accumulation of activated and ex- hausted CD8 cells (9–13), as well as ... See full document
8
A Repression-derepression Mechanism Regulating the Transcription of Human Immunodeficiency Virus Type 1 In Primary T Cells
... CD4 cells. This re- pressor acts through the distal PRRE that is also the NFAT-binding ...T cells, the activator is trans- ferred to the cytoplasm, has a lower DNA affin- ity and is functionally ... See full document
14
Efficiency of Cell-Free and Cell-Associated Virus in Mucosal Transmission of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus
... of cell-associated virus infectivity, further studies should use in vivo models and perhaps tissues from newly infected patients to determine the relative infectivity of invading cells com- pared to ... See full document
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