Top PDF HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC) AND ITS APPLICATION IN PHARMACEUTICAL ANALYSIS
HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC) AND ITS APPLICATION IN PHARMACEUTICAL ANALYSIS
... term,‟Hydrophilic interaction chromatography” in 1990. This mode of chromatography dates back to earliest days of liquid ...chloroform. HILIC as a complex system involves ...
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“Applications of HPLC in Pharmaceutical Analysis” by P. Ravi Sankar, K. Sai Snehalatha, Shaik. Tabassum Firdose, P. Srinivasa Babu, India.
... polar liquid, such as mixtures of water, methanol, acetonitrile (or) mixtures of ...basic analysis parameters such as Drug, column type, mobile phase composition, flow rate and detector type of a huge ...
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Quantitative structure retention relationships for rapid method development in hydrophilic interaction liquid chromatography of pharmaceutical compounds
... of HILIC on unmodified silica columns in pharmaceutical analysis can be found in a recently published review ...are hydrophilic phases with silanol groups and siloxane bridges, which can ...
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Simultaneous untargeted and targeted metabolomics profiling of underivatized primary metabolites in sulfur-deficient barley by ultra-high performance liquid chromatography-quadrupole/time-of-flight mass spectrometry
... using hydrophilic interaction liquid chromatography (HILIC) [4, 12, 21, ...22]. HILIC methods required a delicate, careful optimization, and relatively longtime column ...
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A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry
... liquid chromatography and gas chromatography is well known ...the HILIC method used in the current study the sugars tagged with the 2 ...
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Development of generic methods for the analysis and purification of polar compounds by high performance liquid chromatography
... in pharmaceutical formulation development and also RPLC, where in both cases the primary solvent is water with a small concentration of organic modifier used to aid ...However HILIC mobile phase is somewhat ...
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Practical observations on the performance of bare silica in hydrophilic interaction compared with C18 reversed phase liquid chromatography
... of HILIC compared with ...in HILIC for basic compounds, due to the lower viscosity of the mobile phases used and resul- tant enhanced solute diffusivity, and that also longer columns were applicable ...
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Evaluating the Adsorbed Water Layer on Polar Stationary Phases for Hydrophilic Interaction Chromatography (HILIC)
... Hydrophilic interaction chromatography (HILIC) offers practical advantages to the separation of polar compounds over reversed-phase liquid chromatography (RPLC) and has been ...
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DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry
... comprehensive analysis of methylation profiles to narrow down 102 age-related CpG sites in ...statistical analysis. The prac- tical application still relies on bisulfite sequencing or next generation ...
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Modern mass spectrometric techniques applied to occupational hygiene analysis
... LC/MS analysis, using electrospray ionisation, over their LC/UV ...Gas chromatography combined with flame ionisation detection (FID) and mass spectrometry (MS) has also been used to detect ...simultaneous ...
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Validation and application of reversed-phase high-performance liquid chromatography for quantitative analysis of acid orange 7 and Sudan II in blusher products
... high-performance liquid chromatography (RP-HPLC) method for the determination of acid orange 7 (AO7) and Sudan II (SII) in blusher ...the analysis of AO7 and SII in commercial blusher products, and ...
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Simultaneous estimation of esomeprazole and domperidone by UV spectrophotometric method
... determined, analysis requires only the measuring of the absorbance of the sample solution at two wavelengths selected, followed by a few simple ...routine analysis in quality control ...
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Isolation and screening of lovastatin producing microorganisms
... layer chromatography and the estimation of lovastatin was calculated ...layer chromatography it was observed that, both commercial lovastatin and the sample spots had same Rf ...performance liquid ...
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Using high performance liquid chromatography (HPLC) in pharmaceutical industry: a short review
... A blend of two (or more) of these solvents is used as the mobile phase in a HPLC analysis. The proportions of the different solvents in the blend act to adjust the polarity of the mobile phase. This is combined ...
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Identification of N Methyl Bis(2 (Alkyloxy Alkylphosphoryloxy)Ethyl) Amines by LC HRMS/MS
... chemicals. Liquid chromatography coupled with high-resolution tandem mass spectrometry (LC-HRMS/MS) is one of the most favored analytical tech- niques for CWC related chemicals owing to its ...
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Spectrophotometric determination of Phenylephrine hydrochloride and Salbutamol sulphate drugs in pharmaceutical preparations using diazotized Metoclopramide hydrochloride Mouyed Q. Al-Abachi|Sadeem S. Abed
... (hydroxymethyl) phenol (SLB) is a selective β2-agonist antiasthmatic. Its primary action is to stimulate adenyl cyclase which catalyzes the formation of cyclic adenosin monophosphate[22]. The drug is official in ...
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Determination of atmospheric organosulfates using HILIC chromatography with MS detection
... Due to the atmospheric abundance of organosulfates and their importance in SOA formation, analytical methods have been developed to detect them in ambient aerosol by a range of off-line and on-line instrumentation, ...
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Determination of Salicylate ion by Potentiometric Membrane Electrode based on Zinc Aluminium Layered Double Hydroxides-4(2,4-dichlorophenoxy)Butyrate Nanocomposites
... The lifetime of each membrane electrode depends on the one or more of component in the structure loss, while contacting with aqueous solution. Zn/Al-DPBA nanocomposite which is used as an ionophore has sufficient ...
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Simultaneous determination of seven hydrophilic bioactive compounds in water extract of Polygonum multiflorumusing pressurized liquid extraction and short-end injection micellar electrokinetic chromatography
... The sample was prepared by optimized PLE method. The developed MEKC method was employed for the determination of seven hydrophilic compounds in dif- ferent samples of He-Shou-Wu from different regions of China. ...
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Analytical Method Development and Validation of Assay for Carvedilol Tablets by RP-HPLC, HPTLC and UV Spectroscopy
... of pharmaceutical science, Sulur and ...in Pharmaceutical Analysis, R V S college of Pharmaceutical Sciences, Sulur, Coimbatore, which is affiliated to The Tamilnadu ...
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