[PDF] Top 20 Identification of expression quantitative trait loci by the interaction analysis using genetic algorithm

... In this study, we applied a GA to detect eQTL interactions, which showed comparable performance to an exhaustive search with a smaller number of evaluations. The reduc- tion in computing time becomes greater as the ... See full document

... linkage analysis of gene expression transcripts of members of Centre d'Etude du Polymorphisme Humain (CEPH) Utah families to determine the heritability of transcripts and the evidence for regulatory ... See full document

... individual genetic variants was typically modest, suggesting that individual genetic variants identified by GWAS may only accounted for a very small amount of the genetic risk and heritability of ... See full document

... Eight quantitative trait loci (QTLs) were associated with rice quality, consisting of two QTLs on chromosomes 1 and 9 for amylose content; three QTLs on chromosomes 8, 9, and 10 for protein content; ... See full document

... of genetic linkage map on rubber tree (2n=36) was conducted by using RAPD markers data through ...conducted using MAPMAKER/EXP ...marker analysis through t-test was known that marker C13-2000 ... See full document

... risk loci are located in non-coding or poorly an- notated regions making the interpretation of their role in disease etiology ...eQTL analysis has emerged as an important tool to help understanding the ... See full document

... considerable genetic component; however, little is known about the underlying genetic ...used trait-correlated expression analysis, screening for expression quantitative ... See full document

... cial interaction; language and communication develop- ment; and restricted or circumscribed interests and repetitive behaviors ...of genetic variants involved in autism has been confounded by phenotypic, ... See full document

... A Bayesian method for mapping linked quantitative trait loci (QTL) using multiple linked genetic markers is presented.. Parameter estimation and hypothesis testing was [r] ... See full document

... The arginine pathway has the highest pair wise genetic correlation between traits by any measure than any other pathway. All seven traits in this pathway share a QTL on chromosome III and there is no other QTL for ... See full document

... Actb: Expression levels of each gene were normalized using three genes, Actb, Gapd, and Ppia, to correct variations in RNA quality among individual ...different loci were mapped for Kclr, Psat1, and ... See full document

... Gene expression, as a heritable complex trait, has recently been used in many genome-wide linkage ...each trait may be considered as evidence of a genetic contribution to the total phenotypic ... See full document

... analyses in the GAW19 pedigrees. In the manuscript [2], heritability varied substantially among the transcript levels, and the median was 22.5 %. In the published ana- lysis, eQTL were identified by mapping the ... See full document

... QTL analysis to the field of multinormal asymptotic distribution of the parameter breeding such as marker-assisted selection, it is often of estimates, further elaborations become necessary most concern to predict ... See full document

... find genetic factors affecting Cd uptake and trans- location, we performed expression quantitative trait loci (eQTLs) analysis for genome-wide association studies (GWAS) ... See full document

... an analysis was conducted of sequence variation of all fru proteins between ten recently sequenced Drosophilid genomes including Drosophila melanogaster, ... See full document

... initial analysis sought associations between alleles at individual marker loci and each specific T cell sub- set using a general, parametric statistical model (Proc Mixed; SAS version ...measures ... See full document

... Mapping and analysis of dairy cattle quantitative trait loci by maximum likelihood methodology using milk protein genes as genetic markers.. Casas E, Keele JW, Shackleford SD, Ko ohmarai[r] ... See full document

... As part of ongoing studies regarding the genetic basis of quantitative variation in phenotype, we have determined the chromosomal locations of quantitative trait loci ([r] ... See full document

... average. Using the Poisson approximation, such a threshold is equivalent to controlling the FWE at .... using an FWER controlling method, one may claim that all significances obtained in the study are real, ... See full document