Upon reduction of heme a, a proton is transferred, through the assistance of water molecules, from this residue to a proton-loading site (PLS) or “pump-site”, which is known

Combined DFT and electrostatics study of the proton pumping mechanism in cytochrome c oxidase

(PSPs) in the payments industry by the legislative establishment legal rules and requirements for new entrants into the payment services market... In the area of Payment services

We use comparative genomics, site-directed mutagenesis, and redox kinetics to demonstrate that the B-family of oxygen reductases utilize only one proton input channel, structurally

The similarity in the pH-dependencies and the KIEs of the ED286 and RK481 mutant CytcOs suggests that residues E286 and R481 are mechanistically linked, which is consistent with

[ISWC09a] Daniel Gruhl, Meenakshi Nagarajan, Jan Pieper, Christine Robson, Amit Sheth, Context and Domain Knowledge Enhanced Entity Spotting in Informal Text, The

Upon ET, the first proton (fast reaction) is transferred to the PLS (His291), while subsequent transfer of the second ‘‘chemical’’ proton to the binuclear center (slow reaction)

In the second case (case (ii)) where transfer of the substrate proton to the catalytic site is linked to a structural change, proton transfer to the pump site must be much faster

Data collected from health professionals delivering and referring to the service have been submitted in a linked paper (manuscript) in this journal at the same time;

Rhodobacter sphaeroides functions as a proton pump much like the major enzymes of the heme- copper oxidase family.. In similar experiments with succinate as

based differential evolution (ODE) algorithm using opposition based learning approach to train a feed-forward neural network (FNN) that is found to be effective for identification

In most com- puter simulations in the past, only subunit I was used (in very few cases subunit II was included) due to the reduced computational cost. However, it is believed

Place the ATD hook tip at the most secure portion of the prosthesis with a secure purchase: the lingual embrasure space between the pontic and premolar abutment (Fig. 16 Place hook

We focus on the dynamics and the free energy profiles of the excess proton and the surrounding protein environment near the active sites, and in particular, how the proton

en-japan inc., at its Board of Directors’ meeting held on May 24, 2013, decided to implement a stock split program, adopt the unit share system, revise its dividend projection and

Furthermore, with preincubation of TNF- α -primed neutrophils with PECAM-1, the level of soluble intercellular cell adhesion molecule-1 (sICAM-1), a marker of endothelial

LXR activation did not inhibit nuclear translocation of NF-kappaB1 p50, indicating that the mechanism of LXR-dependent repression of inflammatory genes does not involve limiting

These findings could indicate that increased production of nitric oxide by diff erent kidney cells and structures might also play a role in the progression of gentamicin-induced