[PDF] Top 20 Improving the Magnetic Resonance Imaging Contrast and Detection Methods with Engineered Magnetic Nanoparticles

... functionalizing magnetic nanoparticles have been an area of the extensive research and development in the biomedical and nanomedicine ...understood, magnetic nanoparti- cles, especially iron oxide ... See full document

... Methods: High-resolution nuclear-magnetic-resonance spectroscopy and MR studies on sucralose solution phan- tom were performed to detect the chemical exchange saturation transfer (CEST) property of ... See full document

... as contrast agents for magnetic resonance imaging and can be used for cancer ...oxide nanoparticles and called SPION, for "Superparamagnetic Iron Oxide ... See full document

... The carbon coating provides an effective oxidation bar- rier and prevents corrosion in magnetic core materials. Hydrophilic carbon coating on iron oxide nanoparticle cores endows better dispersibility and ... See full document

... low detection limit, since negative effects on the sensitivity may result from a disproportionate increase of r 2 with respect to r 1 , leading to a reduction of the r 1 /r 2 ...the contrast agents on local ... See full document

... iron nanoparticles have been successfully implemented in the diagnostics due to the possibility to guide them using an external magnetic fi eld ...[89,90]. Magnetic resonance imaging ... See full document

... Other methods for imaging detection of ovarian can- cers have been ...molecular imaging probes for the detection and quantification of tumor- associated metabolites in ovarian ... See full document

... Cross-sectional imaging with computed tomography or magnetic resonance imaging is routinely used to detect and diagnose liver lesions; however, these examinations can provide additional ... See full document

... Neutron capture therapy is one of the treatment methods for treating early cancer, mainly using 10 B con- taining molecules. 10 B is non-reactive atom that absorb low-energy and break into 4 He 2+ and 7 Li 3+ ... See full document

... oxide nanoparticles has been intensively developed in the past years because of their technological interest for biomedical ...uniform nanoparticles with well-defined sizes, shapes, and other physical ... See full document

... to magnetic nanoparticles (Feridex; Ad-Vance Magnetics Inc, Rochester, IN, USA) significantly improved the uptake of the nanoparticles by the mesenchymal stem ...oxide nanoparticles were ... See full document

... Indeed, our in vitro growth inhibition studies indicate an IC 50 value for PDAC cell lines of approximately 3.0–6.0 µ g of F 2 O 3 (Figure 3). This is a considerably high value considering the dosage of NPs injected in ... See full document

... In contrast, free breathing approaches do not affect patients’ hemodynamics and allow for sub millimeter spatial resolution and increased temporal resolution (~20-40 ms) [175, 177, 178] resulting in im- proved ... See full document

... or magnetic resonance angiography (MRA) to avoid the risks of arterial puncture, including life- threatening hemorrhage, dissection, thrombosis, hematoma, and pseudoaneurysm ... See full document

... medical imaging practice however it is important to calculate the contrast to noise ratio (CNR) of CEST images to quantify the likelihood of distinguishing between diseased and surrounding normal ... See full document

... A biologically responsive MRI contrast agent that utilizes the cleavage of short peptides would be an extremely useful diagnostic tool in experimental animals and humans. This chapter describes the synthesis and ... See full document

... salts in aqueous solution by adding sodium hydroxide (2 m). In brief, 2.43 g of ferric ion and 0.89 g of ferrous ion were dissolved in deionized water. After that, 20 mL of sodium hydroxide was rapidly added to ... See full document

... There are several limitations in our study. Firstly, the sample size of lymph nodes examined was relatively small. Therefore, the comparison of sensitivity and spe- ci fi city between contrast-enhanced CT and MRI ... See full document

... or imaging agents, where surface or bulk erosion, diffusion through the polymer matrix, swelling followed by diffusion, or stimulation by the local environment results in the sustained and con- trolled release of ... See full document

... of detection of small bowel lesions with either MRI ...oral contrast medium in the colon with MRFT renders the two MRI protocols identical for the ...enables contrast delivery to be ...with ... See full document