[PDF] Top 20 Increased dynamin expression precedes proteinuria in glomerular disease
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Increased dynamin expression precedes proteinuria in glomerular disease
... 3. Glomerular dynamin protein levels are increased in human proteinuric ...for dynamin (A–D) or cathepsin L (E–H) in a healthy control subject (A, E), a patient with diabetic nephropathy (B, ... See full document
9
Angiotensinogen Expression Is Enhanced in the Progression of Glomerular Disease
... chronic glomerular disease and diabetic ...AGT expression of the diseased glomeruli in the progression of glomerular ...progressive proteinuria and glomerular crescent formation, ... See full document
10
Proteinuria: is it all in the foot?
... The glomerular filtration barrier. Blood enters the glomerular capillaries and is filtered across the endothelium and the glomerular basement membrane and through the filtration slits between ... See full document
5
uPAR isoform 2 forms a dimer and induces severe kidney disease in mice
... the expression of suPAR protein in fat tissue and release into the blood circulation ...monitor proteinuria development and progression, spot urine was col- lected periodically from the above-mentioned ... See full document
15
Endocytic pathways mediating oligomeric Aβ42 neurotoxicity
... tagged dynamin with anti-myc antibody 9E10 (Sigma; 1:5000), Flag- tagged AP180-CT with Flag antibody M2 (Sigma, 1:5000), HA tagged RhoA with rat HA antibody 3F10 (Roche Applied Science; 1:2500), and appropriate ... See full document
11
Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass
... that glomerular transcapillary pressure was reduced significantly by converting enzyme inhibition and by AII blockade but not by the combination regimen (delta P: group 1, 49 +/- 1 mmHg; group 2, 42 +/- 1 mmHg; ... See full document
7
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival
... induces expression of ...ing increased CatL staining in TGF-β1 Tg ...showing increased CatL staining in glomerulus of 3-week-old Cd2ap –/– mice ... See full document
17
Increased glycosphingolipid excretion associated with proteinuria
... with proteinuria of various etiologies was examined to determine if proteinuria alone was associated with significant ...of proteinuria examined, the level of glycosphingolipids in the urine was ... See full document
6
Role of dynamin, synaptojanin, and endophilin in podocyte foot processes
... of dynamin in the stability of podocyte foot processes using a conditional gene KO strategy, and demonstrated that podocyte-selective KO of Dnm1 and Dnm2 resulted in severe proteinuria, renal failure, and ... See full document
12
TNF-α Up-regulates Renal MIF Expression in Rat Crescentic Glomerulonephritis
... TNFbp treatment caused only a partial reduction in glomerular MIF expression on Day 1 of disease compared with expression in saline- treated animals, and this did not affect glomerular m[r] ... See full document
9
Proteins and Other Biocolloids of Urine in Health and in Calculous Disease I Electrophoretic Studies at pH 4 5 and 8 6 of Those Components Soluble in Molar Sodium Chloride
... TRACINGS OF ELECTROPHORETIC MIGRATION PATTERNS OF NORMAL HUMAN PLASMA AND OF URINARY PROTEINS IN HEALTH AND IN THREE DISEASE STATES ACCOMPANIED BY INCREASED PROTEINURIA Veronal buffer, p[r] ... See full document
12
Histopathological Study of Glomerular Disaese (in Patients with Significant Proteinuria): A Study of 50 Cases
... Amyloidosis is classified according to the major component of its fibrils. There is substantial overlap in renal clinicopathologic presentations of amyloid (AL) and amyloid A (AA). Glomeruli are involved in 75 to 90% of ... See full document
92
Ebola Virus Glycoprotein Toxicity Is Mediated by a Dynamin-Dependent Protein-Trafficking Pathway
... Ebola virus causes a highly pathogenic infection resulting in rapid failure of multiple organ systems and in death in many cases. The highest mortality rates are observed with the Zaire subtype, one of four types ... See full document
7
The relation between estimated glomerular filtration rate and proteinuria in Okayama Prefecture, Japan
... and proteinuria as classified by age group (Table ...± proteinuria in their third and fifth decades was significantly lower than that in women without pro- ...?B proteinuria in their third and ... See full document
5
Leukotriene D4 is a mediator of proteinuria and glomerular hemodynamic abnormalities in passive Heymann nephritis
... and glomerular filtration rates, increased transcapillary hydraulic pressure difference, pre- and postglomerular resistances, and decreased ultrafiltration coefficient in PHN ...rats. Glomerular LTB4 ... See full document
10
Influence of antidiuretic hormone on peritoneal membrane area and permeability
... The increase in GFR then could be the result of increased renal blood flow, increased glomerular permeability, increased glomerular basement membrane area, and/or an increase in hydrosta[r] ... See full document
8
Blockade of Oxidative Stress by Vitamin C Ameliorates Albuminuria and Renal Sclerosis in Experimental Diabetic Rats
... renal disease. It is characterized functionally by proteinuria and albuminuria and pathologically by glomerular hypertrophy, mesangial expansion and tubulointerstitial fibrosis; these findings are ... See full document
9
Angiotensin converting enzyme inhibition ameliorates glomerular filtration of macromolecules and water and lessens glomerular injury in the rat
... on glomerular hemodynamics and permselectivity and on subsequent sclerosis was studied in male MWF/Ztm rats which spontaneously develop proteinuria and glomerular structural ...reduced ... See full document
10
Physiological complications in chronic kidney disease
... of disease specific clinical action ...decreasing proteinuria have been found effective to combat against ...active disease, malignant hypertension (ii) slowing progression (iii) reducing ... See full document
6
RENAL CLEARANCES OF GRASS POLYSACCHARIDE: OBSERVATIONS ON GLOMERULAR POROSITY AND ON THE RELATION OF THIS FUNCTION TO PROTEINURIA IN RENAL DISEASE
... Observations on proteinuria equality of Cp and Car can hardly be attributed to The decrease in the ratio Cp/Cm found in hy- tubular reabsorption of this inulin-like polysacpertensive dis[r] ... See full document
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