[PDF] Top 20 Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors
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Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors
... Pituitary tumors are the second most common intracranial neoplasms, comprising 10-15% of diagnosed brain tumors [1, ...Some pituitary tumors are considered “functioning” and ... See full document
12
Upregulation of programmed death 1 on T cells and programmed death ligand 1 on monocytes in septic shock patients
... the PD-1/PD-L1 pathway in a model of sepsis, which showed that the pathway played a pathologic role in altering microbial clearance, the innate inflammatory response, and accelerated apoptosis ... See full document
9
<p>A Molecular Epidemiological Analysis Of Programmed Cell Death Ligand-1 (PD-L1) Protein Expression, Mutations And Survival In Non-Small Cell Lung Cancer</p>
... between PD-L1 expression level and TMB is consistent with the expectation that more somatic mutations lead to a higher probability of neo-antigens, which is likely to attract more in fi ltrating ... See full document
13
<p>Immunological nomograms predicting prognosis and guiding adjuvant chemotherapy in stage II colorectal cancer</p>
... an increased expression of T-helper 1 and cytotoxicity- related genes and helped predict tumor recurrence and ...the programmed cell death 1 protein (PD-1) and the ... See full document
16
The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC
... anti-programmed death-1 (PD-1)/programmed death ligand-1 (PD-L1) monoclonal antibody has a good effect in the treatment of non-small cell lung ... See full document
6
Original Article PD-L1 blockade improves immune dysfunction of spleen dendritic cells and T-cells in zymosan-induced multiple organs dysfunction syndromes
... CD86, programmed death (PD-1), programmed death ligand 1 (PD-L1), paired immunoglobulin-like receptor B (PIR-B) or T-cell proliferation in serum, ... See full document
10
Original Article Programmed death-1 and PD-1 ligand-1 expression in early onset gastric carcinoma and correlation with clinicopathological characteristics
... and expression patterns of programmed death-1 (PD-1) and its ligand PD-L1 in young and older GC ...investigated expression of PD-1 and ... See full document
10
Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer
... and ligand suppresses T cell receptor signaling, and limits immune ...molecule programmed cell death-1 (PD-1) and its ligand programmed cell death-1 ... See full document
11
Pembrolizumab and salvage chemotherapy in EGFR T790M-positive non-small-cell lung cancer with high PD-L1 expression
... a programmed cell death ligand 1 (PD-L1) expression level that increased from ,25% to ...high PD-LI ... See full document
5
The Expression of Programmed Death Ligand-1 within Stages of Oral Squamous Cell Carcinoma: Immunohistochemical Analysis
... research, PD-L1 positivity was mostly seen in male gender (n-66) than in ...higher expression of PD-L1 in ...reported increased expression of PD-L1 in female ... See full document
10
Utility of PD-L1 immunohistochemistry assays for predicting PD-1/PD-L1 inhibitor response
... of programmed cell-death receptor (PD-1) and its associated ligand (PD-L1) have gained significant attention from the oncology ...community. PD-L1, typically ... See full document
6
<p>Positive correlation between programmed death ligand-1 and p53 in triple-negative breast cancer</p>
... that PD-L1 is up-regulated in various malignant tumors and is associated with poor ...that PD-L1 was highly expressed in TNBC than in non-TNBC, and the positive rate of PD- ... See full document
9
Immune biomarkers of treatment failure for a patient on a phase I clinical trial of pembrolizumab plus radiotherapy
... cell death protein 1 (PD-1). PD-1 is expressed by T cells and interacts with its ligands programmed cell death protein ligand 1 (PD-L1) ... See full document
7
Intralymphatic histiocytosis in a patient with lung adenocarcinoma treated with pembrolizumab: a case report
... anti-programmed death (PD-1) antibody, has shown favorable antitumor efficacy in NSCLC patients [1, ...of programmed death ligand 1 (PD-L1) ... See full document
5
Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1
... adenocarcinoma. PD-L1 expression in her original primary tumor was observed at the interface of tumor and normal tissue and there was a dense CD8 + lymphocytic infiltrate ...file 1: Table ... See full document
8
Effect of neoadjuvant chemotherapy on tumor infiltrating lymphocytes and PD L1 expression in breast cancer and its clinical significance
... Hematoxylin and eosin-stained (HES) slides from pre- treatment core biopsy and post-neoadjuvant resection specimens were scored for stromal TILs based on Immuno-Oncology Biomarker Working Group guide- lines [12, 26]. ... See full document
11
Impaired dendritic cell functions in lung cancer: a review of recent advances and future perspectives
... checkpoint PD-1/PD-L1 on DC has been partly ...that PD-1 blockade-acti- vated DC–CIK cells exhibit superior anti-tumor potency in several advanced solid tumors including ... See full document
11
Immune characterization of breast cancer metastases: prognostic implications
... Overall survival (OS) was defined as the time from first relapse to death from any cause. Alive patients were censored at the date of last follow-up. Median OS was estimated using the Kaplan–Meier method and ... See full document
10
CLEC3B as a potential diagnostic and prognostic biomarker in lung cancer and association with the immune microenvironment
... CLEC3B expression groups according to the median expression of ...high expression ADC, whereas in the CLEC3B high expression group of SCC, many gene sets related to immune activation were ... See full document
15
Wnt/beta-catenin pathway: modulating anticancer immune response
... gene expression signature in human metastatic melanoma ...induced expression of the transcription repressor ATF3, which suppressed the transcription of ... See full document
12
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