[PDF] Top 20 -induced apoptosis in neonatal cardiomyocytes
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-induced apoptosis in neonatal cardiomyocytes
... The apoptosis of cardiomyocytes was exam- ined by a TUNEL ...Germany). Apoptosis was quantified as the percentage of healthy (no apoptosis) cardiomyocytes, and normalized to the ... See full document
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p53 and the hypoxia induced apoptosis of cultured neonatal rat cardiac myocytes
... cultured neonatal cardiomyocytes to hypoxia induces apoptotic cell ...induce apoptosis in normoxic myocytes ...the neonatal myocardium and maintained in cell cultures showed no signs of ... See full document
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Original Article MicroRNA-182-5p protects H9c2 cardiomyocytes from hypoxia-induced apoptosis by down-regulation of PTEN
... MicroRNAs (miRNAs) are produced endoge- nously and are short noncoding RNAs which regulate target messenger RNA translation by binding to the 3’ untranslated region of mRNA transcript, thereby leading to the degradation ... See full document
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Original Article An RNA-Seq screen of the dithiothreitol-induced apoptosis response in chicken cardiomyocytes
... Abstract: Cardiomyocytes in postnatal heart are terminally differentiated and thus possess limited capacity to re- ...of cardiomyocytes through apoptosis and necrosis can lead to heart failure and ... See full document
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Original Article Effect of HSP70 on cardiomyocyte apoptosis induced by endoplasmic reticulum stress
... SD neonatal rat car- diomyocytes, and HSP70 antisense oligonucle- otide technology was applied to inhibit the HSP70 ...stress-induced apoptosis, flow cytometry was used to detect apoptosis ... See full document
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Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes
... of apoptosis in neutro- phils and adult cardiac ...in apoptosis of cardiac myocytes, we used a potent and specific inhibitor of the VPATPase, bafilomycin ...in neonatal cardiomyocyte apoptosis ... See full document
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Original Article miR-190 protects cardiomyocytes from apoptosis induced by H
... We then discovered the deep mechanism through which miR-190 protect H9c2 cells from oxidative stress injury. Western blot was car- ried out to investigate the protein expression level. The results showed that miR-190 ... See full document
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-induced apoptosis in cardiomyocytes via microRNA-19b/AKT/mTOR signaling pathway
... bolic diseases, suggesting that Irisin could be therapeutic for metabolic disease and other disorders which are linked to cardiovascular diseases such as coronary artery disease, abdominal aortic aneurysm, heart failure, ... See full document
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miR-30e-5p Mitigates Hypoxia-Induced Apoptosis in Human Stem Cell-Derived Cardiomyocytes by Suppressing Bim
... To elucidate the potential mechanism of miR-30e-5p in the regulation of hypoxia-induced apoptosis. We first identified the putative targets of miR-30e-5p, via in silico analysis using miRanda ... See full document
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Original Article Influence of silencing toll-like receptor 4 with RNA interference on cardiomyocytes apoptosis induced by isoproterenol
... 5, cardiomyocytes were divided into four groups: ...the cardiomyocytes were treated with ISO of 1 umol/L; ...V-PE/7-AAD Apoptosis Detection ... See full document
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Building and re building the heart by cardiomyocyte proliferation
... that induced cardiac expression of a known inhibitor of innervation in zebrafish leads to reduced cardiomyocyte proliferation after ventricular injury and disrupts ...the neonatal mouse heart also reduces ... See full document
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Original Article Cardiac hypertrophy is positively regulated by long non-coding RNA PVT1
... cultured neonatal mouse cardiac ...in cardiomyocytes significantly reduced (P < 0.05) Ang II-induced increase of cell size in terms of cell surface area (by ...of cardiomyocytes and might ... See full document
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Effects of Hypoxia on Oxidative Stress, Autophagy and Apoptosis in Cardiomyocytes
... Apoptosis is the process of programmed cell death that occurs during heart development [13]. Caspase-3 is a common effector of most apoptotic pathways and is able to cleave several target proteins whose ... See full document
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β1 adrenoceptor stimulation promotes LPS induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation
... myocyte apoptosis, we used a PKA inhibitor, KT5720, to treat adult mouse cardiomyocytes 1 hour prior to DOB or/ and LPS stimulation, and examined apoptosis-associated molecules in ...on ... See full document
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MiR-499-5p protects cardiomyocytes against ischaemic injury via anti-apoptosis by targeting PDCD4
... myocardial apoptosis warrant further ...regulate cardiomyocytes proliferation and differentiation [25-26], and it could protect cardiomyocytes from H 2 O 2 -induced apoptosis ... See full document
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Junctophilin-2 Protects Cardiomyocytes against Palmitate-induced Injury
... pathway-induced apoptosis is regulated by B-cell lymphoma 2 (Bcl-2) family proteins (102) which are in the outer membrane of ...Fas-mediated apoptosis can also induce mitochondrial damage through the ... See full document
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Silencing of hepcidin enforces the apoptosis in iron-induced human cardiomyocytes
... Cardiomyocyte apoptosis can result in a loss of con- tractile tissue, compensatory hypertrophy of myocardial cells, reparative fibrosis, and heart ...on cardiomyocytes from previous studies is ... See full document
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Reactive Oxygen Species Related Noncoding RNAs as Regulators of Cardiovascular Diseases
... imbalance induced by altered ROS generally influences signaling pathways that contribute to cardiomyocytes’ apoptosis, ER stress, and autophagy, which ultimately contribute to a wide range of ... See full document
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3,3′-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis
... inducing apoptosis of cardiomyocytes. Cardiomyocyte apoptosis is a key cause of many cardiac diseases, including heart failure, atherosclerosis and sepsis-induced cardiac insufficiency ... See full document
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Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes
... The concentration of intracellular free calcium was recorded continuously by laser confocal scanning micro- scopy. The average cytosolic Ca 2+ concentration in a single cell was determined using the fluorescent probe ... See full document
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