[PDF] Top 20 INDUCED INSULIN RESISTANCE IN THE RABBIT

... Resistance to the hypoglycemic action of commercial crystalline beef and pork insulin was induced in the rabbit by the repeated subcutaneous injection of crystalline insulin incorporated[r] ... See full document

... dexamethasone induced insulin resistance in rats [14] , the aim of the present study was to evaluate the α- glucosidase inhibitory activity and antioxidant properties of aqueous extract and ethyl ... See full document

... suppress insulin signaling in muscle and (b) reduce insulin- mediated changes in systemic glucose ...diet–induced insulin resistance, possibly due to reduced inflammatory gene ... See full document

... Glucocorticoids are a powerful tool used to treat a range of human illness- es, including autoimmune diseases and cancer, and to prevent rejection fol- lowing organ transplantation. While lifesaving for many, they come ... See full document

... were induced by dexamethasone to con- struct an insulin resistance model, and insulin resistance model cells were treated with different concentrations of metformin ...in ... See full document

... Nuclear factor, erythroid derived 2, like 2 (Nrf2) is a ubiquitously expressed transcription factor that regulates a series of prosurvival genes (21), with an emerging protective role in type 2 diabetes in mice (22) and ... See full document

... cause insulin resistance in humans, skeletal muscle glycogen and glucose-6-phosphate concentrations were measured every 15 min by simultaneous 13C and 31P nuclear magnetic resonance spectroscopy in nine ... See full document

... of insulin secretion and augmentation of hepatic glucose ...to insulin, and the relative contributions of peripheral ...hepatic resistance to impaired insulin action, have not been ...the ... See full document

... of insulin resistance and beta-cell dysfunction in glucocorticoid-induced diabetes were determined in Wistar and Zucker (fa/fa) ...stimulated insulin secretion, indicating insulin ... See full document

... was induced and ii) hsa-miR-181a that was repressed in relation to T1D and ...hepatic insulin resistance in T2D pa- tients, this miRNA has been suggested as potential diag- nostic marker for this ... See full document

... Abstract: Glucocorticoids therapy is the most common cause of secondary iatrogenic osteoporosis.The bone loss occurs predominantly due to a decrease in bone formation, although increased bone resorption also occurs. ... See full document

... Mini-osmotic pump studies. Control and JAK2A mice were implanted with 28-day Alzet mini-osmotic pumps (Durect Corporation) to deliver recombinant mouse GH at a dose of 5 mg/kg/d in GH buffer. At the end of 28 days, mice ... See full document

... Adiponectin. In 3T3-F442A adipocytes, both LPV (4.0 ng/ mL ± 0.4; p = 0.002) and RTV (7.0 ± 1.0; p = 0.001) but not ATV (14.2 ± 2.4) caused downregulation in secreted adiponectin protein in comparison to the ... See full document

... potent insulin sensitizer, enhances insulin action in white adipocytes: Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity ... See full document

... the insulin-induced Akt phosphorylation in fully differentiated human adi- ...the insulin-induced Akt phosphorylation was clearly diminished by IL-8; it was abrogated by PD98059 or ...Akt ... See full document

... neomycin resistance marker under control of the phosphoglycerate kinase-promoter (PGK-neo) and a lacz gene with a nuclear localization sequence (nls-lacz) located immedi- ately downstream of the 5′ arm, thus ... See full document

... Insulin resistance (IR) is a major public health problem that can lead to many dangerous medical disorders and early ...experimentally induced-IR in rats. IR was induced by the ingestion of ... See full document

... Plasma insulin was measured by radioimmu- noassay (EMD Millipore) for hyperinsulinemic-euglycemic clamps or ELISA (Mercodia) for hyperinsulinemic-hyperglycemic ... See full document

... The seeds of this plant have been reported for many pharmacological activities like anti-inflammatory, antibacterial, larvicidal, antiviral, antifungal, anticancer, anthelmintic, antioxidant, analgesic, antipyretic, ... See full document

... metabolized, insulin-stim- ulated glucose uptake in individual tissues can be estimated by determining the tissue content of ...plasma insulin, FFA, and salicylate ... See full document