[PDF] Top 20 Induction of human B cell antigens in non T cell acute lymphoblastic leukemia
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Induction of human B cell antigens in non T cell acute lymphoblastic leukemia
... Ia+CALLA+ non-T cell acute lymphoblastic leukemia (ALL) express an antigen (B1) found on all normal B ...tumors. Non-T cell ALL lines and tumor cells ... See full document
11
Targeting IRAK1 in T-Cell acute lymphoblastic leukemia
... in T-ALL Transcriptional analysis of the expression level of 65 receptor and receptor-associated kinases in 32 T-ALL (test series) and normal thymic subsets (cell-sorting described in Supplementary ... See full document
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B cell origin of non T cell acute lymphoblastic leukemia A model for discrete stages of neoplastic and normal pre B cell differentiation
... of B cell associated and restricted antigens on tumor cells isolated from 138 patients with non-T cell acute lymphoblastic leukemia (non-T ... See full document
10
Prognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia
... the induction phase with the clinical outcome of adult B cell acute lymphoblastic leukemia ...of B-ALL, age ≥14 years, were ...blood cell (WBC) count (WBC-0), as ... See full document
11
The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia
... pediatric B cell acute lymphoblastic ...two human leukemia cell lines AT-2 and REH, which express ETV6-RUNX1, suggested that SPIB was one of the top of the genes that were ... See full document
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Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses
... Metastases to the breast and axilla are rare and account for approximately 2% of all mammary malignancies [1,2]. The most common metastatic lesion to involve the breast is a metastasis from a contralateral mammary cancer ... See full document
5
P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines
... with T cell acute lymphoblastic leukemia (T-ALL) were screened for mutations of the p53 tumor suppressor ...of T-ALL relapse patient ...a B cell line (HABL) ... See full document
8
Subset derivation of T cell acute lymphoblastic leukemia in man
... Normal human peripheral blood T cells can be characterized as belonging to either the TH+2 or TH-2 T-cell ...of T cells are TH+2, whereas 80% are TH- 2 utilizing specific ...shether ... See full document
7
The molecular basis of T cell acute lymphoblastic leukemia
... mouse T cell progenitor cells confers self-renewal capacity to this normally non–self-renewing population ...stem cell properties and the oncogenic effects of LMO2 in T cell ... See full document
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Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways
... and harvested on ice. Lysates were prepared in a Western lysis buffer (20 mM Tris [pH 7.5], 150 mM NaCl, 1% Triton X-100, sodium pyrophosphate, β -glycerophosphate, EDTA, Na 3 VO 4 , and leupeptin) by repeatedly passing ... See full document
9
Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas
... of human T cell acute lymphoblastic leukemia (T-ALL) [1–3] and several murine T-ALL models, including ATM − / − thymic lymphomas [4 – ...Both human and ... See full document
5
SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines
... Quantitative PCR was carried out using a 7500 Applied Biosystems real-time PCR system following the manufac- turer's protocol (Darmstadt, Germany). TaqMan probes (Applied Biosystems) were used to quantify human ... See full document
5
Childhood pre B cell acute lymphoblastic leukemia with translocation t(1;19)(q21 1;p13 3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report
... ALL: Acute lymphoblastic leukemia; aMCB: Array-proven high-resolution multicolor banding; B-ALL: B cell acute lymphoblastic leukemia; BM: Bone marrow; Cdks: ... See full document
6
Profile of blinatumomab and its potential in the treatment of relapsed/refractory acute lymphoblastic leukemia
... cytotoxic T-cells to CD19+ target B-cells inducing serial perforin-mediated ...in non-Hodgkin’s lymphomas, but the most important trials have been conducted in relapsed/refractory (R/R) acute ... See full document
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<p>T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with <em>NOTCH1</em> mutation as a good prognostic factor</p>
... Childhood Lymphoblastic Leukemia (GBTLI-ALL 99/09) or to ALL Berlin- Frankfurt- Münster (BFM-ALL 95 and 2002) ...and T-cell phenotype of both proto- ...of induction therapy have ... See full document
11
MYC as therapeutic target in leukemia and lymphoma
... of human tumors, being more prevalent in hematologi- cal ...of leukemia and ...in acute lymphoblastic leukemia, acute myeloid leukemia, lymphoproliferative, and ... See full document
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Different stages of B cell differentiation in non T acute lymphoblastic leukemia
... for B cell-related markers (BA-1 and B1 monoclonal antibodies, as well as cytoplasmic immunoglobulins [CyIg]) in the cALL cases showed that at least one B cell marker could be detected either ... See full document
9
Prediction of outcomes by early treatment responses in childhood T-cell acute lymphoblastic leukemia: a retrospective study in China
... [12–15]. T- ALL patients are more likely to have a worse steroid re- sponse than B-ALL patients [8, 10, ...during induction therapy is a well- established predictive factor and patients with ≥ 25 % ... See full document
11
Protein kinase inhibitors for acute leukemia
... Acute leukemia is subdivided into acute myelocytic leukemia (AML) and acute lymphoblastic leukemia (ALL) [1, ...all acute leukemias in adults, and the cure rates ... See full document
7
CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia
... Many North American groups have developed CAR-T products and started clinical trials with anti-CD19 therapies for B-cell malignancies such as non-Hodgkin lymphoma (NHL), chronic lymphoid ... See full document
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