[PDF] Top 20 The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia
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The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia
... [10]. Patients with CLL are considered in nPR when they are in remission after ...of bone marrow lymphoid infiltration in CLL with nPR after treatment with nucleoside ana- logues Oudat et ...of ... See full document
5
The Role of STAT3 in the Pathogenesis of Chronic Lymphocytic Leukaemia
... in patients with CLL and higher numbers are associated with poor prognosis (Gonzalez-Rodriguez et ...CLL patients have defects in their normal immune function resulting in a lack of ...show chronic ... See full document
250
Clinical and Haematological Pattern of Chronic Lymphocytic Leukaemia in Sudanese Patients
... Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of mature- appearing lymphocytes in the blood, bone marrow, lymph nodes, and ...The Chronic lymphocytic ... See full document
10
Chemotherapy plus Ofatumumab at Standard or Mega dose in relapsed CLL (COSMIC) trial: study protocol for a phase II randomised controlled trial
... BMA/T: Bone marrow aspirate/trephine; CI: Confidence interval; CLL: Chronic lymphocytic leukaemia; CR: Complete remission; CR(i): Complete remission with incomplete marrow ... See full document
11
French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
... of patients studied are small, and their disease severe, such that additional studies are required to determine the best use of ...for patients at high ... See full document
8
Review Article The role of TP53 network in the pathogenesis of chronic lymphocytic leukemia
... It is generally accepted that CLL TP53 mutation is strongly associated with 11q deletion. The miR-34b (GenBank 407041)/miR-34c (GenBank 407042) are coded on 11q23 and miR-34a (GenBank 407040) on 1p36 [4, 26]. ... See full document
7
NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma
... period. Patients were assessed by an experienced Hematologist and fulfilled IWCLL criteria for B-CLL or WHO criteria for ...23 Patients with B-CLL were confirmed to be untreated and Binet stage A at ... See full document
14
Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS
... and bone marrow samples using ESI Ion Trap mass spectrometry using solid phase extraction and to evaluate the drug levels in plasma and bone marrow samples of the CML ... See full document
7
Oral Complications In Patients Undergoing Chemotherapy
... in patients receiving chemotherapy, bone marrow transplantation and local head and neck area (Treister, developing mucositis depends upon that about 40% of patients treated with ... See full document
5
Case Report Pulmonary leucostasis and trisomy 12 in a young patient with chronic lymphocytic leukemia: a case report and review of literature
... diagnosed patients with CLL, accounting only for 10% to 20% of newly diagnosed ...15,490 patients diagnosed with CLL in 2009 in the United States were age 34 or younger ...acute lymphocytic leukemia ... See full document
5
Expression of Autoreactive B Cell (B-1a) in Periodontal Health and Disease: An Immunohistochemical Study.
... Seymour et al 1979 88 have shown in their study that in the pathogenesis of chronic inflammatory periodontitis, there is a conversion from a stable T cell lesion to a progressive B cell lesion. Evidence for the ... See full document
90
The effect of bone marrow microenvironment on the functional properties of the therapeutic bone marrow derived cells in patients with acute myocardial infarction
... the bone marrow microenvironment of patients with ST-elevation myocardial infarction (STEMI) can affect the functional- ity of the cells used in autologous cell ...with bone marrow ... See full document
11
To treat or not to treat: metabolomics reveals biomarkers for treatment indication in chronic lymphocytic leukaemia patients
... in leukaemia have received much attention in the ...that leukaemia cells oxidise fatty acids and that they uncouple oxidative phosphorylation in order to shift ATP production from fatty acid oxidation to ... See full document
15
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin
... As expected, a combined treatment with dabrafenib and trametinib induced a complete regression of MM skin lesions, which is still maintained (after 12 months of treatment). Whether these inhibitors were also effect- ive ... See full document
6
Expression Profiling of Microarray Gene Signatures in Acute and Chronic Myeloid Leukaemia in Human Bone Marrow
... In the recent years, microarray research has shown gene signatures for haematological malignancies in general, and for AML in particular (2). These findings pave the way for more specific diagnosis, prognosis, and ... See full document
18
Pulmonary Leukaemic Infiltration in Patient with Chronic Lymphocytic Leukaemia
... undergone chemotherapy due to chronic lymphocytic leukemia (CLL) in the previous ...words: Chronic Lymphocytic Leukaemia, bron- chopulmonary leukemic infiltration, pulmonary in- ... See full document
5
Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies
... important patients’ clinical and molecular characteristics are summarized in Additional files 1-3: Tables ...MDS patients, the number of AZA cy- cles received up to the time of BM aspiration is indi- cated ... See full document
11
THE LOCAL BLOOD FLOW IN HUMAN BONE MARROW IN LEUKEMIA AND NEOPLASTIC DISEASES AS DETERMINED BY THE CLEARANCE RATE OF RADIOIODIDE (I131)
... The findings appear to demonstrate a selective increase in blood flow in the bone marrow in acute leukemia and in some cases of chronic lymphocytic leukemia and multiple myeloma, and str[r] ... See full document
13
Understanding chronic lymphocytic leukaemia (CLL)
... Chromosome studies (cytogenetics): Chromosome tests can find out about any abnormalities in your chromosomes connected to your CLL. For example, parts of chromosomes may be missing, or you may have an extra chromosome. ... See full document
33
Bone Marrow Microenvironment-mediated Resistance to Chemotherapy in Leukemia
... to chemotherapy agents, such as ...to chemotherapy with hypoxia-inducible factor 1 (HIF-1) being the master transcriptional regulator of hypoxia response (75, ... See full document
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