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Inhaled Nitric Oxide: A Premature Remedy for Chronic Lung Disease?
... of lung vascu- lar resistance, and the experience of prolonged expo- sure to high concentrations of oxygen and positive pressure ventilation may cause lung injury that in- terferes with delivery of iNO to ... See full document
6
Inhaled Nitric Oxide in Extremely Premature Neonates With Respiratory Distress Syndrome
... (tROP); chronic lung disease (CLD), which we defined as a requirement for supplemental oxygen or any form of pressure support at 36 weeks’ corrected gestational age (CGA); and periventricular ... See full document
11
Use of Inhaled Nitric Oxide in Preterm Infants
... or chronic lung disease (relative risk ...or chronic lung dis- ease if a higher dose of iNO (20 ppm) was used after > 7 days of age, as observed in the NOCLD ... See full document
9
Inhaled Nitric Oxide in preterm infants: a systematic review and individual patient data meta-analysis
... injury. Inhaled Nitric Oxide, an effective therapy for pulmonary hypertension and hypoxic respiratory failure in the full term infant, has also been studied in preterm ...or chronic ... See full document
10
Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension
... for chronic Obstructive Lung Disease [GOLD] criteria with a postbronchodila- tor forced expiratory volume in 1 second (FEV 1 )/forced vital capacity (FVC) ... See full document
9
Surfactant Function and Composition in Premature Infants Treated With Inhaled Nitric Oxide
... The NO CLD Trial was a randomized, blinded, controlled trial of iNO treatment performed at 21 centers. Infants with birth weights of 500 to 1250 g who still required ventilatory support between 7 and 21 days of age were ... See full document
10
Plasma Biomarkers of Oxidative Stress: Relationship to Lung Disease and Inhaled Nitric Oxide Therapy in Premature Infants
... of lung disease supports the previous ...lung disease. In addition, plasma protein levels may be lower, and lung disease more severe, in infants who are less devel- opmentally ... See full document
9
Neonatal Ventilation With Inhaled Nitric Oxide Versus Ventilatory Support Without Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure: The INNOVO Multicentre Randomised Controlled Trial (ISRCTN 17821339)
... preterm lung disease [presenting with lung disease immediately after birth and randomized at ⱕ3 days of age], chronic preterm lung disease [presenting with lung ... See full document
13
NIH Consensus Development Conference Statement: Inhaled Nitric-Oxide Therapy for Premature Infants
... Nitric oxide is a gas that is ubiquitously produced in the human ...the lung, the heart, the ner- vous system, the immune system, and stem cells, and on the development of ...of nitric ... See full document
9
Inflammatory Markers and Mediators in Tracheal Fluid of Premature Infants Treated With Inhaled Nitric Oxide
... and disease se- verity in premature infants at 7 to 21 days; (2) to inves- tigate the effect of iNO on the inflammatory profile, to assess both safety and the potential mechanisms of NO in lung ... See full document
11
NIH Consensus Development Conference Statement: Inhaled Nitric-Oxide Therapy for Premature Infants
... Nitric oxide is a gas that is ubiquitously produced in the human ...the lung, the heart, the ner- vous system, the immune system, and stem cells, and on the development of ...of nitric ... See full document
7
Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease
... The Lung Health Study was supported by contract N01-HR-46002 from the Division of Lung Diseases of the National Heart, Lung, and Blood ...Heart, Lung, and Blood Institute contracts R01HL089856 ... See full document
10
Reducing Variation in the Use of Inhaled Nitric Oxide
... Our fi rst step toward obtaining CTICU staff buy-in for iNO initiation and weaning guidelines was review of the patients and iNO usage from the pre- vious year. The inconsistent initiation and weaning (or not weaning) was ... See full document
8
Pitfalls, Problems, and Progress in Bronchopulmonary Dysplasia
... Bronchopulmonary dysplasia is a chronic lung disease associated with premature birth and characterized by early lung injury. In this review we discuss some pitfalls, problems, and ... See full document
14
Clinical application of exhaled nitric oxide measurement in pediatric lung diseases
... Interestingly, inhaled or systemic corticosteroid administration results in dose dependent reductions of FeNO levels ...improved lung function and reduced airway reactivity ...or lung function ... See full document
10
Role Of Nitric Oxide In Embryonic Heart Development And Adult Aortic Valve Disease
... Many factors may regulate the expression of NOS3 during embryonic heart development. Bio-informatics analysis of the mouse NOS3 locus showed three canonical Tbx5 binding sites, two of which are flanked by Gata binding ... See full document
206
Pulmonary Nitric Oxide Synthases and Nitrotyrosine: Findings During Lung Development and in Chronic Lung Disease of Prematurity
... postmortem lung blocks were prepared for immunohistochemistry using antibodies to each nitric oxide synthase isoform and to ...of chronic lung ... See full document
11
Comparisons of mortality and pre-discharge respiratory outcomes in small-for-gestational-age and appropriate-for-gestational-age premature infants
... that premature SGA neonates were at a higher risk of mortality than pre- mature AGA infants (Odds Ratio ...for chronic lung disease and death before 28 days of birth and 36 weeks ... See full document
7
Correlation between fractional exhaled nitric oxide and sputum eosinophilia in exacerbations of COPD
... using Lung Function Machine (MS-pneumo + aps; JAEGER; German) by the experienced technician in accordance with the 2014 recommendations of the Chinese National Guidelines of Pulmonary Function ... See full document
7
Inhaled Nitric Oxide for Preterm Infants: A Systematic Review
... RESULTS. Eleven randomized, controlled trials of inhaled nitric oxide therapy for preterm infants were found. The trials were grouped into 3 categories according to the entry criteria, that is, entry ... See full document
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