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[PDF] Top 20 inhibits the expression of Th17 cell-related transcription factors in MRL_1pr mice

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inhibits the expression of Th17 cell-related transcription factors in MRL_1pr mice

inhibits the expression of Th17 cell-related transcription factors in MRL_1pr mice

... treatment: MRL_1pr mice were randomly divided into 2 groups, including control group and As 2 O 3 ...The mice were intraperitoneally injected with As 2 O 3 at ...[19]. Mice in the control ... See full document

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Original Article The effects of Langchuangding on the Th17 cell-related transcription factors BATF and RORγt in MRL_1pr mice

Original Article The effects of Langchuangding on the Th17 cell-related transcription factors BATF and RORγt in MRL_1pr mice

... Abstract: Th17 cells participate in the occurrence and development of systemic lupus erythematosus ...reported. MRL_1pr mice were divided into 3 groups, a model group with normal feeding, and predni- ... See full document

6

Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice

Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice

... in Th17 development has been ...induce Th17 differentiation in mice ...to Th17 cells in humans (18, ...for Th17 differentiation by human T cells ...used mice lack- ing the ... See full document

10

Original Article Changes of Th17/Treg cell and related cytokines in pancreatic cancer patients

Original Article Changes of Th17/Treg cell and related cytokines in pancreatic cancer patients

... of Th17 cells and Treg cells in the peripheral blood of patients with pancreatic cancer through analyzing the changes of the related genes and cytokines ...of Th17 cells and Treg cells were detected ... See full document

7

Epstein-Barr Virus LMP2A Interferes with Global Transcription Factor Regulation When Expressed during B-Lymphocyte Development

Epstein-Barr Virus LMP2A Interferes with Global Transcription Factor Regulation When Expressed during B-Lymphocyte Development

... regulatory transcription factors. Two Ets transcription factors, ...transgenic mice (27). Spi-B-deficient mice are defec- tive in BCR-stimulated proliferation, and this effect is ... See full document

10

Research Progress of Th17/Treg Cells and Their Transcription Factors in Autoimmune Diseases

Research Progress of Th17/Treg Cells and Their Transcription Factors in Autoimmune Diseases

... of Th17 in IBD remains controversial. Some believe that Th17 cells can mediate intestinal inflammation by releasing inflammatory factors, while others believe that Th17 cells have a protective ... See full document

10

Identification of novel HIV 1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome wide transcriptional approach

Identification of novel HIV 1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome wide transcriptional approach

... transcripts related to different biological functions including: cytokines/ chemokines, TCR, and transcription regulators ...in Th17 versus Th1 included known Th17-specific cytokines (IL-22, ... See full document

23

Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease

Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease

... directly inhibits Th17 cell generation and promotes transdifferentiation of Th17 cells into IL- 17 – FOXP3 + CD4 + T ...gene expression and blocks p38 activity to prevent SGK1 ... See full document

20

Effect of γ secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis like skin inflammation

Effect of γ secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis like skin inflammation

... elevated expression of Th17 cells and IL-17A in psoriatic lesion and peripheral circulation as well as their positive association with the disease severity have been reported in numerous studies [8, ... See full document

10

Toll like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

Toll like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

... ZO-1 expression in mouse intestinal lysates was determined, in which case membranes were simultane- ously incubated with rabbit polyclonal anti–ZO-1 (Zymed, catalog 40-2300) and mouse monoclonal anti–β-actin ... See full document

15

The Role of Arx in Specification and Maintenance of Pancreatic Islet α-Cells

The Role of Arx in Specification and Maintenance of Pancreatic Islet α-Cells

... stem cell based therapies have multiple obstacles, including lack of cellular homogeneity, inability to correctly differentiate, and questions regarding patient safety ...stem cell population ... See full document

166

Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies

Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies

... the expression of schizophrenia-related cognitive endophenotypes in animal models for selected genes either directly associated with increased risk for schizophrenia, or candidate genes involved in ... See full document

39

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy

... reverse transcription coupled quantitative polymerase chain reaction (qPCR) to confirm the global expression profiling results ...global expression profiling results, 82 of the 179 genes identified ... See full document

19

Expression of the E2F family of transcription factors during murine development

Expression of the E2F family of transcription factors during murine development

... tion factors have been found to be key effectors of the cell cycle (Martin et ...tion, cell growth arrest and apoptosis has been well established (Nevins, 1998; DeGregori et ...E2F ... See full document

11

Lineage  and stage specific expressed CYCD7;1 coordinates the single symmetric division that creates stomatal guard cells

Lineage and stage specific expressed CYCD7;1 coordinates the single symmetric division that creates stomatal guard cells

... activated cell sorting (FACS)-isolated cells of the late stomatal lineage (Adrian et ...predicted expression in GMCs with transcriptional and translational reporters ...the expression pattern, we ... See full document

10

Phosphatase and tensin homolog (PTEN) in antigen presenting cells controls Th17 mediated autoimmune arthritis

Phosphatase and tensin homolog (PTEN) in antigen presenting cells controls Th17 mediated autoimmune arthritis

... of Th17 cells in vivo As the development of CIA critically depends on the generation of Th17 cells [12, 33] and we have found re- duced levels of Th17-related cytokines in the serum of myeloid ... See full document

11

FGF acts directly on the somitic tendon progenitors through the Ets
transcription factors Pea3 and Erm to regulate scleraxis
expression

FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression

... the transcription factors Pea3 and Erm, and the inhibitors MAPK phosphatase 3 (Mkp3), similar expression to FGF (Sef) and sprouty ...their expression (Firnberg and Neubuser, 2002; Kawakami et ... See full document

12

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

... Inflammation is a major contributor to secondary brain injury after ischemic stroke and thus represents a potential target for therapy (Anrather and Iadecola 2016). Beyond its well-characterized role in calcium ... See full document

13

Whey Protein Intake Modulates Lipid Metabolism by Transcriptionally Affecting PPARs and SREBP1c and Their Downstream Enzymes in Mice

Whey Protein Intake Modulates Lipid Metabolism by Transcriptionally Affecting PPARs and SREBP1c and Their Downstream Enzymes in Mice

... affects expression patterns of genes re- lated to lipid metabolism in ...the transcription factors, peroxisome proliferator-activated re- ceptors (PPARs), and their target enzymes, hormone-sensitive ... See full document

11

αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice

αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice

... Blockade inhibits Th17 cell differentiation and protects from EAE in ...progression. Mice were immunized (day 1) and given daily injections of cRGD or control peptide for 7 days, and their ... See full document

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