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18 results with keyword: 'inotuzumab ozogamicin pediatric patients relapsed refractory lymphoblastic leukemia'

Inotuzumab ozogamicin in pediatric patients with relapsed/refractory acute lymphoblastic leukemia

Hepatic adverse event pro fi le of inotuzumab ozogamicin in adult patients with relapsed or refractory acute lymphoblastic leukaemia: results from the open-label, randomised, phase

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2021
A chemotherapy-free regimen for Ph + acute lymphoblastic leukemia: are we there yet?

Impact of minimal residual disease status in patients with relapsed/refractory acute lymphoblastic leukemia treated with inotuzumab ozogamicin in the phase III INO-VATE trial.

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7
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2021
Inotuzumab ozogamicin in the treatment of relapsed/refractory acute B cell lymphoblastic leukemia

Phase II study of the salvage mini-hyper-CVD in combination with inotuzumab ozogamicin (INO) for adult patients with relapsed/refractory (R/R) acute lymphoblastic leukemia

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8
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2020
How to INFLUENCE reimbursement decisions as a patient advocate?

National Institute for Health and Care Excellence, TA 541: Inotuzumab ozogamicin for treating relapsed or refractory B-cell acute lymphoblastic leukaemia (19 September 2018)

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2021
Inotuzumab ozogamicin in clinical development for acute lymphoblastic leukemia and non-Hodgkin lymphoma

Sequential Combination of Low-Intensity Chemotherapy (Mini-hyper-CVD) Plus Inotuzumab Ozogamicin with or without Blinatumomab in Patients with Relapsed/Refractory

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9
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2020
Inotuzumab ozogamicin: a CD22 mAb–drug conjugate for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia

In 2017, as a result of the positive Phase 3 clinical trial comparing inotuzumab ozogamicin to standard chemotherapy, the drug (under the trade name Besponsa) was approved

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2020
Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia

Nelarabine has been primarily evaluated in adult and pediatric patients diagnosed with T-cell lymphoblastic lymphoma or leukemia whose disease is refractory or has relapsed while

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2020
The potential of CAR T therapy for relapsed or refractory pediatric and young adult B-cell ALL

therapies such as chimeric antigen receptor (CAR) T cells, which have revolutionized the treat- ment of pediatric patients with relapsed or refractory B-cell acute

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2020
Dose-related efficacy and toxicity of gemtuzumab ozogamicin in pediatric acute myeloid leukemia

Gemtuzumab Ozogamicin (Mylotarg [Registered]) Expanded Access Protocol for Treatment of Patients in the United States with Relapsed/ Refractory Acute Myelogenous Leukemia Who

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2021
Recent advances in the biology and treatment of B-cell acute lymphoblastic leukemia

Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome-Positive B-Precursor Acute Lymphoblastic Leukemia Following

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2020
Recent advances on blinatumomab for acute lymphoblastic leukemia

Complete hematologic and molecular response in adult patients with relapsed/refractory philadelphia chromosome-positive B-precursor acute lymphoblastic leukemia following

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2020
Immunotargeting relapsed or refractory precursor B-cell acute lymphoblastic leukemia – role of blinatumomab

Complete molecular and hematologic response in adult patients with relapsed/refractory (R/R) Philadelphia chromosome-positive B-precursor acute lymphoblastic leukemia

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2020
Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab

Blinatumomab can induce molecular remission in pediatric patients with posttransplant relapsed B-precursor acute lymphoblastic leukemia and facilitate subsequent

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8
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2021
Treating relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia: liposome-encapsulated vincristine

High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia.

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10
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2020
Assessment of clinical immunogenicity of inotuzumab ozogamicin in patients with non-Hodgkin lymphoma and acute lymphoblastic leukemia

For NHL clinical studies, determination of the presence of anti-rituximab antibodies followed a sequential process that included (1) screening and (2) concurrent titer de-

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2020
Acute Lymphoblastic Leukemia in Adults

Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphia- positive acute lymphoblastic leukemia

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2021
Inotuzumab ozogamicin in the management of acute lymphoblastic leukaemia

Current clinical trials investigating Inotuzumab in ALL include; a Phase I/II studying 2 different doses of Inotuzumab in combination with chemotherapy as frontline treatment in

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2021
Profile of inotuzumab ozogamicin and its potential in the treatment of acute lymphoblastic leukemia

Results of two major studies are awaited: a larger Phase I trial to evaluate pharmacokinetics, levels of MRD, and response is ongoing (B1931010 trial), and a Phase III pivotal

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8
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2020

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