[PDF] Top 20 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
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Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
... Edinburgh, UK), Jennifer Huff man (MRC Human Genetics Unit, Edinburgh, UK), Susan Campbell (MRC Human Genetics Unit, Edinburgh, UK), Jaspal Kooner (Imperial College London, London, ... See full document
13
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
... (EGA study and dataset codes: EGAS00001000713 and EGAD00001000776) reference panels which were combined using IMPUTE2 ...49,458 UK BiLEVE samples, imputation quality information scores were ... See full document
141
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
... Health Study, COPACETIC = COPD Pathology: Addressing Critical gaps, Early Treatment & Diagnosis and Innovative Concepts, ECLIPSE = Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points, ... See full document
26
Characterising human lung tissue for biomarkers of EMT fibrosis and functional steroid receptor components in chronic obstructive pulmonary disease (COPD) patients and control subjects
... The study of transgenic mice bearing germ line reporter genes whose expression was driven by epithelial-cell-specific promoters where evidence of formation of fibroblast from epithelial cells by ...in ... See full document
137
Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case–control study
... Data analyses were performed using the Statistical Pack- age for the Social Science 20.0 (SPSS, Inc., Chicago, IL, USA). Continuous variables (age, smoking history, and pulmonary function) were ... See full document
19
Genetic variants affecting cross sectional lung function in adults show little or no effect on longitudinal lung function decline
... Health Study acknowledges the support of the National Health and Medical Research Council of Australia, the Government of Western Australia (Health Department, Sir Charles Gairdner Hospital, PathWest and ... See full document
10
<p>Variation in Assignment of the COPD Patients into a GOLD Group According to Symptoms Severity</p>
... The mMRC dyspnoea scale is an assessment tool that establishes the severity of this symptom in relation to various physical tasks. This scale was developed by the American Thoracic Society as a modification of the ori- ... See full document
9
Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease
... All study patients or their family members signed in- formed consent forms. The protocol was approved by the local institutional human investigations committee (IEC for Clinical Research of Zhongda Hospital, ... See full document
8
<p>GOLD Classifications, COPD Hospitalization, and All-Cause Mortality in Chronic Obstructive Pulmonary Disease: The HUNT Study</p>
... This study was funded by ExtraStiftelsen Helse og Rehabilitering and Landsforeningen for hjerte-og-lungesyke (the Norwegian Extra Foundation for Health and Rehabilitation and the Norwegian Heart and Lung ... See full document
9
A prospective, comparative study of effect of Roflumilast in Chronic Obstructive Pulmonary Disease and its efficacy in reducing exacerbations
... with chronic bronchitis are very likely to be heavy and cyanotic and they are termed “blue bloaters” ...Advanced disease may be accompanied by cachexia, with significant weight loss, bitemporal wasting, and ... See full document
113
Geographical distribution of COPD prevalence in Europe, estimated by an inverse distance weighting interpolation technique
... The IDW interpolation is a simple and intuitive method, easy to handle and interpret, relatively fast for calculations, and easy to compute, which also has the advantage of allow- ing to easily renewing the database, ... See full document
11
Impact of exacerbations on respiratory system impedance measured by a forced oscillation technique in COPD: a prospective observational study
... of obstructive lung disease, including ...excessive lung function decline in COPD, the impact of exacerbations on the results of FOT has not been ...this study was to investigate ... See full document
8
Impulse Oscillometry in the diagnosis of Asthma
... A study was done to evaluate the airway resistance in patients with asthma using impulse oscillometry by comparing the airway resistance in patient who had allergic rhinitis and in patients who did not have ... See full document
204
Costs of illness analysis in Italian patients with chronic obstructive pulmonary disease (COPD): an update
... stronger lung function limitations) are much more likely to show disease progression, leading up to death in a consistent proportion of ...of disease progression from the first approach to the ... See full document
7
<p>Sarcopenia Is an Independent Risk Factor for NAFLD in COPD: A Nationwide Survey (KNHANES 2008–2011)</p>
... a chronic in fl ammatory disease that mainly occurs in the peripheral airways and lung par- enchyma, and is characterized by macrophages, neutrophils, and type 1 cytotoxic T ... See full document
10
The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK
... our study had some ...this study was based on prescribing ...of pulmonary function data, which can contribute to overdiagnosis, and the absence of health status ...this study evaluated ... See full document
8
New evidence of increased risk of rhinitis in subjects with COPD: a longitudinal population study
... population-based study was to investigate the risk of developing noninfectious rhinitis (NIR) in subjects with chronic obstructive pulmonary disease ...population-based study ... See full document
7
Genetic evidence linking lung cancer and COPD: a new perspective
... stratifying lung cancer susceptibility has several possible clinical utilities, including targeted prevention and targeted screening for early ...their smoking history. Given that nearly 50% of those ... See full document
13
Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies
... better lung function. Although Lepeule et al. had lung function and methylation data at two time points (388 men, average 4 years 7 months apart) au- thors reported changes in lung ... See full document
10
Outpatient pulmonary rehabilitation – rehabilitation models and shortcomings in outpatient aftercare
... Asthma is a chronic inflammation of the respiratory sys- tem. In the treatment of asthma priority is given to the avoidance of symptoms and the interference of activities. Especially for COPD, positive effects of ... See full document
9
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