[PDF] Top 20 The effect of non insulin dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle
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The effect of non insulin dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle
... impaired glucose transport in obesity and ...of insulin-regulated Glut 4 translocation in skeletal muscle was assessed using confocal laser scanning ...study ... See full document
10
Transmembrane glucose transport in skeletal muscle of patients with non insulin dependent diabetes
... for glucose metabolism in skeletal muscle is a key feature in non-insulin- dependent diabetes mellitus ...of glucose metabolism are involved is still ... See full document
10
Glucose transport in cultured human skeletal muscle cells Regulation by insulin and glucose in nondiabetic and non insulin dependent diabetes mellitus subjects
... human skeletal muscle culture (HSMC) system, which retains cellular integrity and insulin responsiveness for glucose transport was employed to evaluate glucose transport ... See full document
9
Mechanism of impaired insulin stimulated muscle glucose metabolism in subjects with insulin dependent diabetes mellitus
... nonoxidative glucose metabolism which was z 50% lower in the IDDM ...of glucose oxidation which were not significantly different be- tween ...that insulin resistance in patients with poorly con- ... See full document
7
Effect of the antilipolytic nicotinic acid analogue acipimox on whole body and skeletal muscle glucose metabolism in patients with non insulin dependent diabetes mellitus
... causing insulin resistance in skeletal muscles in patients with non-insulin-dependent diabetes mellitus ...acute effect of the antilipolytic nicotinic acid analogue ... See full document
10
Hyperglycemia normalizes insulin stimulated skeletal muscle glucose oxidation and storage in noninsulin dependent diabetes mellitus
... decreased glucose storage could occur as a consequence of decreased glucose uptake, and that GS is impaired ...secondarily. Muscle glucose uptake in 15 diabetic subjects was matched to 15 ... See full document
10
Impaired free fatty acid utilization by skeletal muscle in non insulin dependent diabetes mellitus
... seven muscle enzyme markers of glycolytic and aerobic-oxidative ...by skeletal muscle were lower while glucose oxidation was increased (P < ... See full document
9
Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin resistant patients with non insulin dependent diabetes mellitus
... and glucose oxidation and the muscle activities, as well as the immunoreactive protein and mRNA levels of the rate-limiting enzymes in glycogen synthesis and glycolysis, glycogen synthase (GS) and ... See full document
10
Comparison of Salivary Glucose and Serum Glucose Concentration in Non-Insulin Dependent Diabetes Mellitus Patients: A Case Control Study
... residual insulin secretion in Type-2 DM to limit ketoacid formation and prevent the development of clinical ...that obesity, especially of long duration, is an important risk factor for the development of ... See full document
131
Glutamine:fructose 6 phosphate amidotransferase activity in cultured human skeletal muscle cells: relationship to glucose disposal rate in control and non insulin dependent diabetes mellitus subjects and regulation by glucose and insulin
... intact muscle, in that we have shown in fresh skel- etal muscle biopsy specimens that GFA activity is correlated with glycated hemoglobin levels ...of glucose in the culture medium increase GFA in ... See full document
8
Exercise modulates postreceptor insulin signaling and glucose transport in muscle specific insulin receptor knockout mice
... First, skeletal muscle is a heterogeneous tissue containing multiple cells of different origin, and there- fore it is conceivable that other insulin sensitive cells are partially responsible for the ... See full document
9
Intact insulin stimulation of skeletal muscle blood flow, its heterogeneity and redistribution, but not of glucose uptake in non insulin dependent diabetes mellitus
... femoral muscle (71 6 6 vs. 96 6 7 m mol/kg mus- cle·min, P , 0.02) glucose uptake were significantly de- ...creased. Insulin increased mean muscle blood flow similarly in both groups, from ... See full document
10
Thermic effect of infused glucose and insulin in man Decreased response with increased insulin resistance in obesity and noninsulin dependent diabetes mellitus
... normal glucose tolerance (group II), and 13 obese subjects with abnormal glucose tolerance or noninsulin-dependent diabetes mellitus before (group IIIa) and after weight loss of ... See full document
11
Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non insulin dependent diabetes mellitus and obesity
... of insulin-mediated glucose uptake occurs via the translocation of GLUT 4 glucose transporter proteins from an intracellular depot to the plasma ...classic insulin target cell, to better ... See full document
11
Glycogen synthase activity is reduced in cultured skeletal muscle cells of non insulin dependent diabetes mellitus subjects Biochemical and molecular mechanisms
... tained from DuPont-NEN (Boston, MA). Horseradish-conjugated anti–rabbit IgG and the enhanced chemiluminescence Western blot kit were obtained from Amersham Corp. (Arlington Heights, IL). Bovine serum albumin and ... See full document
7
Increased epinephrine and skeletal muscle responses to hypoglycemia in non insulin dependent diabetes mellitus
... (plasma insulin approximately 140 microU/ml), plasma glucose was lowered to 62 +/- 2 mg/dl by 120 ...Hepatic glucose output ([3H-3]glucose) suppressed similarly during euglycemia, but ... See full document
11
Skeletal muscle peroxisome proliferator activated receptor gamma expression in obesity and non insulin dependent diabetes mellitus
... human skeletal muscle at z 10–15% of the level found in adipose tissue, and that this is entirely due to expression of PPAR g 1 ...human skeletal muscle, with the g 1 isoform predomi- nating ... See full document
7
31P nuclear magnetic resonance measurements of muscle glucose 6 phosphate Evidence for reduced insulin dependent muscle glucose transport or phosphorylation activity in non insulin dependent diabetes mellitus
... nonoxidative glucose metabolism was determined by the insulin-glucose clamp technique in conjunction with indirect ...Nonoxidative glucose metabolism which under these conditions is a measure ... See full document
8
In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin dependent diabetes mellitus
... of glucose transport was correlated with the maximum capacity of glucose utilization (r = ...plasma glucose concentrations of diabetic subjects were negatively correlated with both maximum ... See full document
10
Polymorphism in the 5' flanking region of the human insulin gene Relationships with noninsulin dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians
... between insulin and glucose ...for diabetes compared with only 26% (8/31) of diabetics without a class 3 allele (P = ...The insulin gene polymorphism probably plays no important role in the ... See full document
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