[PDF] Top 20 Integrative analysis of gene expression profiles reveals specific signaling pathways associated with pancreatic duct adenocarcinoma
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Integrative analysis of gene expression profiles reveals specific signaling pathways associated with pancreatic duct adenocarcinoma
... whose expression parallels that of CKS2 based on RNA sequencing data from PDAC tis- sues in The Cancer Genome ...6a). Analysis of tumor and non-tumor tissues from our cohort of 102 patients with PDAC showed ... See full document
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Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
... methylation profiles of: 1) Round1 (one cis- platin treatment) ...any specific gene was estimated by its ratio of normalized Cy5 to Cy3 fluorescent signal ... See full document
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Original Article Analysis of whole genomic expression profiles and screening of the key signaling pathways associated with pancreatic cancer
... of pancreatic cancer is thought to be a complex ...of pancreatic cancer and exploring the specific markers for early diagnosis and specific targets of therapy is a key point to prevent and ... See full document
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Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma
... FN1 signaling pathways in pancreatic tumor cells, promoting tumor cell survival and chemoresistance, cell invasion, metasta- sis, and angiogenesis ...FN1 expression and function in the context ... See full document
8
Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells
... of gene expression (27, 28) and the establishment of immunological memory (1, 29–32) in T cells are controlled by TFs that recruit chromatin modifiers and remodelers to tran- scriptional enhancers and ... See full document
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Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells
... Human pluripotent stem cells (hPSCs) can self-renew indefinitely and differentiate into all types of tissues in the body. Therefore, it can be an unlimited source to provide specialized cells for biomedical research and ... See full document
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Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia
... mediate gene ex- pression. Although there has not been any specific methylated gene patterns identified for schizophrenia, there are significant associations between promoter CG islands (CGIs) ... See full document
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The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors
... Cell Signaling), Stat3 (sc-482; Santa Cruz Biotechnology ...Cell Signaling), tubulin (T-5168; Sigma-Aldrich), phosphoserine- 727–Stat3 (pserStat3) (62), CD24 (clone SN3b; Thermo Scientific), and CD44 (clone ... See full document
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Over-expression of CKS1B activates both MEK/ERK and JAK/ STAT3 signaling pathways and promotes myeloma cell drug- resistance
... MEK/ERK signaling pathway may induce some non-specific effects on myeloma cell growth and survival, we constitutively activated the MEK/ ERK signaling pathway by lentivirus-vector-mediated MEK1-cDNA ... See full document
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Identification of miRNA mRNA crosstalk in CD4+ T cells during HIV 1 infection by integrating transcriptome analyses
... target gene expression pro- files still needed to be analyzed in order to elucidate the real miRNA-mRNA relationships in a pairwise ...plots analysis because of the arrays quality problems, which ... See full document
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Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes
... integrin-mediated signaling impacts PRCC and differs between PRCC1 and ...the analysis of five PRCC gene expression datasets derived from Gene Expression Omnibus (GEO) and The ... See full document
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Research Progress of HOXA13/HOTTIP Gene and Digestive Tract Cancer
... Abnormal expression of HOXA13/HOTTIP gene and gastric cancer Han Yang [38] and screened 132 without preoperative chemotherapy of gas- tric cancer patients were collected after operation of carcinoma tissue ... See full document
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Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer’s disease
... different expression of genes in immune and metabolic pathways may be associated with AD ...the expression of genes in these immune and metabolic ... See full document
6
<p>Transcriptome Analysis Reveals Key Genes and Pathways Associated with Metastasis in Breast Cancer</p>
... and pathways involved in metastasis, we overlapped the DEGs and KEGG pathways of the three ...raft associated 2 (ERLIN2), Y-Box binding protein 2(YBX2) and EBF family member 4 (EBF4), had signi fi ... See full document
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Original Article Differences in gene expression profiles and signaling pathways in rhabdomyolysis-induced acute kidney injury
... MAPK signaling path- way. From the Path-Net analysis, we concluded that the MAPK signaling pathway had the most relationships with other signaling ...JUN gene was significantly upreg- ... See full document
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A novel gene-pair signature for relapse-free survival prediction in colon cancer
... The expression level of RFS-related genes in a specific sample underwent pairwise comparison to generate a score for each gene ...first gene of one gene pair had a higher ... See full document
9
The role of PRKG2 in Angus dwarfism
... PTHrP pathways, which are responsible for proper chondrocyte development ...controlling expression of SOX5 and SOX6 ...context specific function of genes in biology and the other possible ... See full document
179
Pathway analysis reveals functional convergence of gene expression profiles in breast cancer
... same analysis in a single data set and identified many lists of genes equally predictive of the ...these gene lists share only a small number of ...typical gene overlap of ...to gene selection ... See full document
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Microarray study of gene expression profile to identify new candidate genes involved in the molecular mechanism of leptin-induced knee joint osteoarthritis in rat
... the gene expression profile in OA by microarray ...OA. Gene expression profile of leptin-induced articular cartilage and healthy rat cartilage were compared using genome-wide microarray ...be ... See full document
9
Clinically relevant genes and regulatory pathways associated with NRAS Q61 mutations in melanoma through an integrative genomics approach
... methylation, gene expression, and miRNA expression to investigate the influence of driver ...mRNA expression, and miRNA expression), including primary tumors and pan-negative melanomas, ... See full document
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