[PDF] Top 20 Interleukin 2 induces the proliferation of mouse primordial germ cells in vitro
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Interleukin 2 induces the proliferation of mouse primordial germ cells in vitro
... ABSTRACT Primordial germ cells (PGCs) are the stem cell precursors of the germ ...both. Interleukin-2 (IL-2) has a growth-promoting activity for T and B-lymphocytes, but ... See full document
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Differentiation of mouse primordial germ cells into female or male germ cells
... ABSTRACT Mouse primordial germ cells (PGCs) migrate from the base of the allantois to the genital ...of mouse PGCs has been studied by culturing them on feeder ...of ... See full document
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Programmed cell death in mouse primordial germ cells
... in mouse PGCs caused by cytokine deprivation came from studies showing that the mouse White spotting (W) and Steel (Sl) loci, known for mutations leading to marked reduction or absence of germ ... See full document
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Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... cell proliferation just prior to meiotic entry in diverse organisms follows a special program of synchronous, incomplete divisions that generates interconnected cell groups known as cysts (Gondos, 1973; Matova and ... See full document
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Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
... the mouse, the primordial germ cells (PGCs) occupy sequentially different tissues of the ...the germ cells (Anderson et ...(E)7.5, germ cells emerge from the ... See full document
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PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells
... stem cells and thereby facilitate its recruitment to PRDM14 target genes [19, 31] or that PRDM14 could activate expression of the PRC2 com- ponent Suz12 ...like cells cultured in vitro lose ... See full document
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Identification of side population cells in mouse primordial germ cells and prenatal testis
... ES cells (Susanto et al., 2008). Al- though PGCs are germ line-committed cells under certain in vivo and in vitro conditions, they can actually transform into embryonal carcinoma (EC) and ... See full document
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... Despite recent considerable progress, much remains to be learned about the mechanisms and the consequences of the epigenetic reprogramming in pre-implantation embryos and in PGCs. As multiple and compound pathways for ... See full document
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Regulation of primordial germ cell development in the mouse
... recombinant mouse SCF added to PGCs growing on their own gonadal somatic cells, significantly increased the number of PGCs without directly stimu- lating their proliferation (Dolci et ...in ... See full document
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DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
... Primordial germ cells (PGCs) are the founding population of cells that will ultimately give rise to the mature ...the mouse embryo are specified by an inductive mechanism that requires ... See full document
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Investigation on the Effect of Low Intensity Ultrasound Stimulation on Mouse Spermatogonial Stem Cell Proliferation and Colonization
... stem cells (SSCs) are the foundation of spermatogenesis and male ...stem cells, SSCs are rare, representing only 0.03 percent of all germ cells in rodent testis ...stem cells, SSCs ... See full document
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Primordial germ cells: the first cell lineage or the last cells standing?
... PGC-like cells derived from human embryonic stem cells maintain NANOG expression, express very low or no PRDM14, and do not express SOX2 (Irie et ...of mouse and humans, and it is not yet clear ... See full document
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AKT signaling promotes derivation of embryonic germ cells from primordial germ cells
... transgenic mouse PGCs, AKT signaling was activated for 1 day only at various time points of primary culture, in the absence of bFGF (data not ...EG cells established in AKT-MER transgenic ...EG cells ... See full document
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Impaired meiotic competence in putative primordial germ cells produced from mouse embryonic stem cells
... that mouse PGCs are derived from a few precursors located at the proximal posterior epiblast, which around ...somatic cells in the male gonadal ridge degrades ...in vitro conditions, male PGCs until ... See full document
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A replication dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells
... somatic cells, an alternative mechanism might exist for global DNA demethylation in the absence of AID functions (Popp et ...– Mouse Genome Informatics), were specifically repressed in PGCs (Kurimoto et ... See full document
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Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells
... To explore the molecular mechanism involved in apoptotic cell death by Nanog KD, the global gene expression profile of each E10.5 PGC was analyzed by a single-cell microarray assay (Kurimoto et al., 2007). A PGC-specific ... See full document
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Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase
... inhibition induces cell-cycle arrest, leading to decrease in tumor cell proliferation and apoptosis ...cancer cells. Thus, the effect of leucine deprivation on cell proliferation and apoptosis ... See full document
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Germes is involved in translocation of germ plasm during development of Xenopus primordial germ cells
... the germ plasm in most PGCs of uninjected ...contained germ plasm in the cortex at stage 12, compared with only ...of germ plasm in these PGCs was very similar to that in DEADSouth-knockdown PGCs ... See full document
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Nodal induces sequential restriction of germ cell factors during primordial germ cell specification
... retained germ cell factor mRNAs, whereas cells under the influence of Nodal reduced both transcription and retention of germ cell factor ...a germ cell fate in time and ... See full document
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Transient translational quiescence in primordial germ cells
... stem cells (Rezza et ...stem cells are also common in cancer and are the bane of chemotherapy; a quiescent cancer stem cell escapes many of the cancer treatments intending to kill the rapidly proliferating ... See full document
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