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[PDF] Top 20 Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

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Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

... investigate interstrain differences in the constitutive activities of Cyp2a5, Cyp1a1/2 and Cyp2b9/10, and Cyp2a5 mRNA expression in the mouse ...investigated differences ... See full document

12

Role of growth hormone and chromatin structure in regulation of sex differences in mouse liver gene expression

Role of growth hormone and chromatin structure in regulation of sex differences in mouse liver gene expression

... male liver is ...in mouse liver and the other two forms are expressed at low levels, as judged by their microarray signal ...Mef2 activity post-translationally, ...resident liver cells ... See full document

350

Differential Interstrain Susceptibility to Vertebrobasilar Dolichoectasia in a Mouse Model

Differential Interstrain Susceptibility to Vertebrobasilar Dolichoectasia in a Mouse Model

... arterial diameter increase of ⱖ 25% compared with controls. 6 In this article, we applied high stringent and clinically relevant criteria in defining the VBD formation and thus changed the arterial diameter increase from ... See full document

6

Tracking the Rhythmic Gene Expression in Mouse Liver

Tracking the Rhythmic Gene Expression in Mouse Liver

... Regulation of mRNA Accumulation by Circadian and Feeding Rhythms. We took advantage of the RNA-Seq technology to decipher the role of transcriptional and posttranscriptional regulations (17) in the establishment of the ... See full document

10

Genetic regulation of sex-specific gene expression in mouse liver

Genetic regulation of sex-specific gene expression in mouse liver

... gene expression in mouse liver (Under the direction of Ivan Rusyn, ...the expression of many genes is thought to play an important role in disease susceptibility, drug metabolism, and ... See full document

55

Marked differences in tissue-specific expression of chitinases in mouse and man

Marked differences in tissue-specific expression of chitinases in mouse and man

... chitinase activity was found to alleviate the inflammation-driven ...tissue-specific expression of both chitinases in mice and compared it to the situation in ...of expression of chitin- ases in the ... See full document

10

Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver.

Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver.

... transgene expression in animal ...gp19K expression in an adenovirus vector would increase transgene persistence, a vector that replaces the E1 region of adenovirus with an expression cassette ... See full document

6

Expression of Vascular endothelial growth factor in normal and tumoral liver mouse cells

Expression of Vascular endothelial growth factor in normal and tumoral liver mouse cells

... transplanted mouse tumors, VEGF expressed itself either in endothelial cells or in the parenchymal ...by differences in the epitope structure among species as has been reported by Zeng et ...in ... See full document

6

Fatigue Alleviation Mechanism of Citric Acid Determined by Gene Expression Analysis in the Mouse Liver

Fatigue Alleviation Mechanism of Citric Acid Determined by Gene Expression Analysis in the Mouse Liver

... gene expression changes in the liver between the distilled water and citric acid ...No differences were observed for the genes Gck, Pfkl, Pklr, Pck1, and G6pc, which are related to glucose metabolism ... See full document

8

Impact of 'Dioxins' on Gene Expression in Mouse Liver in vivo, and in both Rat Liver Cells and Human Blood Cells In Culture

Impact of 'Dioxins' on Gene Expression in Mouse Liver in vivo, and in both Rat Liver Cells and Human Blood Cells In Culture

... vitro liver cell systems using both primary rat hepatocytes and the rat hepatoma cell line H4IIE, impact of the core congeners as well as the group of seven further compounds was investigated by means of ... See full document

337

The impact of human and mouse differences in NOS2 gene expression on the brain’s redox and immune environment

The impact of human and mouse differences in NOS2 gene expression on the brain’s redox and immune environment

... brain expression levels when the HuNOS2 gene is inserted into the mouse genome is ...gene expression is also regulated by non ‘cytokine’- like factors includ- ing β-catenin/Wnt2, epidermal growth ... See full document

15

Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

... these differences were sig- nificant ( p < ...oxidase activity of either BM or LM as compared to ...oxidase activity in both BM and LM; no significant difference was found between the inhibition ... See full document

6

Altered Proteolysis and Global Gene Expression in Hepatitis B Virus X Transgenic Mouse Liver

Altered Proteolysis and Global Gene Expression in Hepatitis B Virus X Transgenic Mouse Liver

... proteolytic activity of proteasome in vitro, and that inhibition of proteasome leads to enhanced viral replication, suggesting that HBX and proteasome interaction plays a crucial role in the life cycle and ... See full document

9

Establishment of Stable Reporter Expression for In Vivo Imaging of Nuclear Factor-κB Activation in Mouse Liver

Establishment of Stable Reporter Expression for In Vivo Imaging of Nuclear Factor-κB Activation in Mouse Liver

... a mouse model for noninvasive quantification of NF-κB activation in the he- patic ...Hepatic expression of φC31o integrase mediated chro- mosomal integration of the pattB-NF-κB-Fluc reporter, resulting in ... See full document

10

Aberrant neuronal activity-induced signaling and gene expression in a mouse
model of RASopathy

Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy

... conditional mouse strain that expresses the overactive Ptpn11 D61Y allele only in the ...global expression of this mutation, this strain is viable and without severe sys- temic phenotype, but shows lower ... See full document

37

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

... in liver of the knockout mice. H&E staining of liver tissue revealed that a small number of hepatocytes with chromatin condensation and cytosolic shrinkage were scattered in the liver lobules of the ... See full document

15

Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen specific Tregs

Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen specific Tregs

... Treg activity might be beneficial for the treatment of autoimmune ...the liver to promote immune tolerance. Expression of the neural autoantigen myelin basic protein (MBP) in the liver was ... See full document

9

Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

... chronic liver injury in mice has important differences compared to human ...EGF expression decreased significantly during chronic liver injury, whereas it has been shown to increase during ... See full document

11

Mouse Model of Carbon Tetrachloride Induced Liver Fibrosis: Histopathological Changes and Expression of CD133 and Epidermal Growth Factor

Mouse Model of Carbon Tetrachloride Induced Liver Fibrosis: Histopathological Changes and Expression of CD133 and Epidermal Growth Factor

... the differences in the response to hepatotoxicity in the livers of ...in liver cir- rhosis in rats but in neither fibrosis nor cirrhosis in mice ...the liver was almost absent in rats after common ... See full document

12

Expression and Interstrain Variability of the YPS3 Gene of Histoplasma capsulatum

Expression and Interstrain Variability of the YPS3 Gene of Histoplasma capsulatum

... numbers of tandem repeats between strains of the same and different RFLP classes suggest plasticity in the locus (Fig. 2B). Heterologous expression of the YPS3 ORF. Whereas con- centrated culture supernatants of ... See full document

7

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