[PDF] Top 20 Investigations of Pyrrole Imidazole Polyamide Effects on DNA Replication
Has 10000 "Investigations of Pyrrole Imidazole Polyamide Effects on DNA Replication" found on our website. Below are the top 20 most common "Investigations of Pyrrole Imidazole Polyamide Effects on DNA Replication".
Investigations of Pyrrole Imidazole Polyamide Effects on DNA Replication
... for polyamide-induced replication stress in an asynchronous population of DU145 human prostate carcinoma cells ...these effects more cell lines should be tested, as each cancer cell line harbors ... See full document
160
First-principles Investigations of Enzymatic Function, Molecular Sensors and Electrical Monitoring of DNA Replication
... during DNA synthesis ...fragment replication cycle starts with the enzyme in the open state in which a template base n is bound between the O and O1 ...new DNA base ...formed DNA base pair by ... See full document
132
Biological Activity of Pyrrole-Imidazole Polyamides in vivo
... from DNA is one of the candidates, with possibly other effects playing a ...5’-WGGWWW-3’ DNA sequence ...Further investigations showed possible mechanisms of polyamide-induced toxicity ... See full document
208
Preclinical Study of DNA-Recognized Peptide Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Progressive Renal Diseases in Common Marmoset
... PI polyamide targeting human TGF-b1 (hTGF-b1). To develop PI polyamide targeting hTGF-b1 (Polyamide) as a practical medicine for progressive renal diseases, we examined the effects of ... See full document
25
Completion of a Programmable DNA Binding Small Molecule Library
... Hairpin pyrrole-imidazole (Py-Im) polyamides are programmable oligomers that bind the DNA minor groove in a sequence-specific manner with affinities comparable to those of natural DNA-binding ... See full document
153
Programming Protein Patterns on DNA Nanostructures with Pyrrole Imidazole Polyamides
... of product 20 after purification. It should be noted that in the course of this study and similar experiments, yields for these types of couplings after HPLC purification rarely exceed 30% and often times were less than ... See full document
131
Targeted Derepression of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat by Pyrrole-Imidazole Polyamides
... input DNA demonstrated that doubling of the DNA input results in a less than twofold increase in ChIP PCR product ...of DNA input, was induced by TSA ...global effects of TSA and showed ... See full document
6
Dna fingerprinting applications in forensic investigations
... that DNA writing is just an examination of a DNA test's arrangement as well as length at discrete areas, a match in DNA writing is dependably a measurable work ...the DNA profile depends on ... See full document
5
Different Modes of Human Papillomavirus DNA Replication during Maintenance
... HPV16 DNA replicated in a manner similar to that of cellular ...of replication profiles between viral and cellular DNA can also be obtained even if different modes of replication were used by ... See full document
9
DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells
... novo DNA synthesis in nondividing ...a DNA damage response (DDR) that involves activation of all three phosphatidylinositol 3-kinase-related kinases (PI3KKs): ATM (ataxia telangiectasia mutated), ATR (ATM ... See full document
20
E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription.
... Adenovirus ElA proteins repress transcriptional activation of various enhancers, including those of Py, and can stimulate DNA replication in quiescent cells, but ElA effects on Py DNA re[r] ... See full document
8
A study of the effects of acid on the polymerisation of pyrrole, on the oxidative polymerisation of pyrrole and on polypyrrole
... A study was undertaken of polypyrroles prepared by oxidative polymerisation, using chemical reagents. It was shown that additional acid added to the ferric chloride mediated polymerisation of pyrrole has a ... See full document
6
Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.
... virus DNA polymerase catalytic subunit, which has intrinsic polymerase and 3 * -5 * exonuclease activities, contains sequence motifs that are homologous to those important for 3 * -5 * exonuclease activity in ... See full document
8
Functionalization of carboxylated multiwall nanotubes with imidazole derivatives and their toxicity investigations
... antitumoral effects. These materials can diffuse into cells and destroy DNA. Functionalization of carbon nanotubes with imidazole derivatives can leave mutual effects on cancerous cells. In ... See full document
8
DNA Replication-Initiation Proteins in Eukaryotic Cells
... Ipi3p is a component of the Rix1 complex (Ipi1p-Ipi2p/Rix1p- Ipi3p), which is required for processing of ITS2 sequences from 35S pre-rRNA and ribosome biogenesis [56-58]. A yeast functional proteomic screen identified ... See full document
8
Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans
... in DNA replication) resulted in increased proliferation in a lung assay of cryptococcosis ...in DNA replication can generate novel traits that facilitate the ability to cause disease and ... See full document
18
Dissecting The Functions Of Atr In Replication Fork Stability
... in DNA replication checkpoint termination and entry into mitosis through its βTrCP ubiquitin ligase-mediated degradation of Claspin, a known replisome component (Yoo et ...bare DNA structure of a ... See full document
204
A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid
... other polyamide interactions that would normally target the minor groove of DNA (39), UMSL1011 stretches across the struc- tured RNA by making contacts with both the bases and the backbone ... See full document
15
Control of initiation of DNA replication in Bacillus subtilis and Escherichia coli
... bound DNA [7]. Compensatory negative writhe at the DUE would facilitate DNA unwinding ...unwound DNA is then stabilized by binding to the ssDNA binding site of DnaA located in the ATPase domain ... See full document
33
DNA evidence and police investigations: a health warning
... same man – but that man was not the confessing kitchen porter, Leicestershire police then decided to undertake the world's first DNA mass screening. No profiles matched the profile of the killer. A year later a ... See full document
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