[PDF] Top 20 3 Iodo 2 methyl 1 phenylsulfonyl 1H indole
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3 Iodo 2 methyl 1 phenylsulfonyl 1H indole
... ring system. The molecular structure is stabilized by a weak intramolecular C—H O hydrogen bond. The crystal struc- ture exhibits weak intermolecular C—H interactions and – interactions between the indole groups ... See full document
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SYNTHESIS, CRYSTAL STUDIES AND PHARMACOLOGICAL ROLE PREDICTION OF 3 IODO 2 METHYL 1 PHENYL SULFONYL 1H INDOLE
... of DHFR of M. tuberculosis reveals opportunities for the design of novel tuberculosis drugs [12]. DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and this is essential for the synthesis ... See full document
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3 Methyl 1 phenyl N (2 thienylmethylene) 1H pyrazol 5 amine
... of 2- carbaldehyde and 2,6-dicarbaldehyde derivatives with a diamine results in open-chain and macrocyclic Schiff bases, respectively (Janusz et ...from 2-thiophene carbaldehyde (Hashemia et ...of ... See full document
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Crystal structure of (E) 2 (4 methoxystyryl) 3 methyl 1 phenylsulfonyl 1H indole
... Indole derivatives exhibit antitumour (Andreani et al., 2001) and antiviral (Kolocouris et al., 1994) activities. The molecular structure of the title compound is illustrated in Fig. 1. The geometric ... See full document
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Sildenafil citrate monohydrate
... name: 1-{[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3- d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperaz- inium citrate monohydrate), C 22 H 31 N 6 O 4 ... See full document
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5,7 Dibromo 1′ methyl 2′ (4 methoxybenzoyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 3′′ 1H indole 2,2′′(3H,3′′H) dione methanol solvate
... A mixture of (E)-3-(p-methoxyphenacylidine)oxindole (1 mmol), 5,7-dibromoisatin (1 mmol) and sarcosine (1 mmol) was stirred at room temperature in aqueous methanol. The resulting crude product ... See full document
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A FASILE SYNTHESIS OF 1 ( 2, 3 – DICHLOROPHENYL ) 4 ( 1 METHYL 3 PHENYL 1H 1,2,4 TRIAZOL 5 YL) PIPERAZINE MOTIFS AND ITS ANTIMICROBIAL ACTIVITY
... To a solution of 4-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)-1H-1,2,4-triazol-3- yl)aniline (5) (200 mg, 0.514 mmol), triethyl amine (0.143 ml, 1.02 mmol) in dichloromethane (10 ml) was added ... See full document
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Crystal structure of 2 [2 phenyl 1 (phenylsulfonyl)ethyl] 1 phenylsulfonyl 1H indole
... bonded sulfonylbenzene rings, respectively, and these two benzene rings are inclined to each other at an angle of 65.45 (16) . The methylene-linked phenyl ring is twisted at an angle of 81.80 (13) from the ... See full document
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Crystal structure of 1 methyl 3 [2,2,2 trifluoro 1 (1 methyl 1H indol 3 yl) 1 phenylethyl] 1H indole
... In the crystal array three intramolecular interactions C3—H3···F1 (2.969 Å), C16—H16···F3 (3.029 Å) and C26— H26···F2 (2.989 Å) of type hydrogen bonds are observed, and in the crystal packing intermolecular contacts of ... See full document
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5 Chloro 4 [(2 chlorobenzoylhydrazono)methyl] 3 methyl 1 phenyl 1H pyrazole
... Cl1 0.0986 (5) 0.0762 (4) 0.1374 (7) −0.0006 (3) 0.0717 (5) 0.0358 (4) Cl2 0.0377 (3) 0.0675 (3) 0.0724 (4) −0.0124 (2) 0.0240 (2) −0.0226 (2) O1 0.0391 (7) 0.0716 (9) 0.0729 (9) ... See full document
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5 Benzyloxy 3 methyl 1 tosyl 1H indole
... methylindole (325 mg, 1.37 mmol) in dry THF (0.9 ml) under ice cooling. After stirring at room temperature for 1 h a solution of 4-methylbenzenesulfonyl chloride (225 mg, 1.18 mmol) in THF (0.9 ml) was added to ... See full document
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Crystal structures of 1 benzenesulfonyl 2 methyl 3 (4 nitrobenzoyl) 2,3 dihydro 1H indole and 1 benzenesulfonyl 2 methyl 3 [(thiophen 2 yl)carbonyl] 2,3 dihydro 1H indole
... For both structures, data collection: APEX3 (Bruker, 2016); cell refinement: APEX3 and SAINT (Bruker, 2016); data reduction: SAINT and XPREP (Bruker, 2016); program(s) used to solve structure: SHELXT2014/7 (Sheldrick, ... See full document
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3 Methyl 1 phenyl 1H pyrazol 5 yl 2,4 dichlorobenzoate
... of 1-phenyl-3-methyl-1 H -pyrazol-5-one (Liu & Li, 2004; ...g, 2 mmol), anhydrous sodium carbonate (0.11 g, 1 mmol), and a catalytic amount of tetrabutylammonium ... See full document
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4′ (3 Chlorophenyl) 1 methyl 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ indan 2,1′′,3′′ trione
... Fig. 1 shows a displacement ellipsoid diagram of the mol- ecule with the atomic numbering ...Table 1. The bond lengths correlate with a variety of N-phenyl-substituted pyrrolidin-2-one systems ... See full document
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4′ (p Methoxyphenyl) 1′ methyl 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 1′′ cyclopentane 2(3H),2′′ dione
... The H atoms were positioned geometrically and were treated as riding on their parent atoms, with aromatic CÐH distances of 0.93 AÊ, methylene CÐH distances of 0.98 AÊ, ethylene CÐH distances of 0.97 AÊ and NÐH distances ... See full document
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4 [(5 Hydroxy 3 methyl 1 phenyl 1H pyrazol 4 yl)phenylmethyl] 5 methyl 2 phenyl 1H pyrazol 3(2H) one ethanol hemisolvate
... C8A—C10A—C17A—C18A 110.58 (17) C25B—C20B—C21B—C22B 0.6 (2) C11A—C10A—C17A—C18A −121.05 (16) N4B—C20B—C21B—C22B −178.97 (15) N4A—N3A—C18A—C17A 0.32 (17) C20B—C21B—C22B—C23B −0.1 (3) N4A—N3A—C18A—C27A −179.89 ... See full document
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1 Methyl 4′ (3 nitrophenyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ indan 2,1′′,3′′ trione
... The total puckering amplitudes (Cremer & Pople, 1975) of rings A, B and C give a quantitative evaluation of the puck- ering and asymmetry parameters. Ring A is in a half-chair conformation, with the lowest asymmetry ... See full document
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1 [1 (4 Fluorophenyl) 2 methyl 5 phenyl 1H pyrrol 3 yl]ethanone
... Data collection: SMART (Bruker, 2000); cell refinement: SAINT (Bruker, 2000); data reduction: SAINT; program(s) used to solve structure: SIR92 (Altomare et al., 1993); program(s) used to refine structure: SHELXL97 ... See full document
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5 Fluoro N (2 methyl 3 oxo 1 thia 4 azaspiro[4 5]dec 4 yl) 3 phenyl 1H indole 2 carboxamide
... The indole ring system (N1/C1–C7/C14) is essentially planar, with the maximum deviations of ...The phenyl (C8–C13) and 1,3-thiazolidine (S1/N3/C16/C17/C19) rings are inclined at the dihedral angles of ... See full document
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(Z) 3 (1 Chloroprop 1 enyl) 2 methyl 1 phenylsulfonyl 1H indole
... The indole derivatives are known to exhibit anti-bacterial and anti-tumour activities (Okabe & Adachi, 1998; Schollmeyer et ...The phenyl ring forms a dihedral angle of 75.07 (8)° with the indole ... See full document
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