[PDF] Top 20 High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARγ/CD36 Pathway in Inflammatory Adipocytes
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High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARγ/CD36 Pathway in Inflammatory Adipocytes
... on inflammatory adipocytes are not completely ...oxLDL uptake of adipocytes, accompanied with upregulation of the mRNA expression of PPARγ and ...CD36. PPARγ is a central ... See full document
10
High systemic levels of low-density lipoprotein cholesterol: fuel to the flames in inflammatory osteoarthritis
... is oxidized in vivo is unknown, ROS is generally seen as the main suspect 51-53 ...others, via scavenger receptors (SR) such as SR-A 54 , CD36 (SR-B) 55 and lectin-type oxLDL receptor 1 (LOX-1; SR-E) ... See full document
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The effect of oxidized low-density lipoprotein combined with adriamycin on the proliferation of Eca-109 cell line
... the high end of the distribution (mainly due to coronary heart disease) and at the low end (mainly due to cancer) ...the inflammatory pathway through NF- B, leading to cell ...that low ... See full document
11
Conversion of very low density lipoprotein to low density lipoprotein A metabolic study of apolipoprotein B kinetics in human subjects
... For this purpose radioiodinated VLDL was reinjected into human subjects and specific activity curves for VLDL-B and LDL-B peptide were obtained study A.. By simultaneous injection of VLD[r] ... See full document
11
Allicin prevents oxidized low density lipoprotein induced endothelial cell injury by inhibiting apoptosis and oxidative stress pathway
... Therefore, we constructed an in vitro oxidative stress model subjected to ox-LDL-exposure and investigated the effect of allicin on ox-LDL-induced vascular endo- thelial injury. Since ox-LDL-induced endothelial cell ... See full document
6
Differential Sensitivity of Lymphocyte Subpopulations to Suppression by Low Density Lipoprotein Inhibitor, an Immunoregulatory Human Serum Low Density Lipoprotein
... to low doses of LDL-In for 24 h augmented, but high doses suppressed, IgG synthesis, suggesting a differential effect on T-helper vs T-suppressor cell ... See full document
10
Leptin decreases the expression of low density lipoprotein receptor via PCSK9 pathway: linking dyslipidemia with obesity
... (p38MAPK) pathway in different cell types [23–25] and the p38MAPK pathway also participated in the regulation of physiological pro- cesses associated with atherosclerosis [25, ...p38MAPK pathway ... See full document
9
Evaluation of pathways for the cellular uptake of high density lipoprotein cholesterol esters in rabbits
... reutilization. Several pathways may be involved in that process. Tracer kinetics were used to estimate the contributions of the various pathways to cellular uptake of HDL CE in rabbits. Tracers of HDL CE, HDL apo ... See full document
17
Relationship between oxidized low-density lipoprotein antibodies and obesity in different glycemic situations
... to oxidized low-density lipoprotein (oxLDL) are a heterogeneous group of antibodies that are controversially discussed to be either pathogenic or ... See full document
8
Lipoprotein lipase mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages
... of lipoprotein triglyceride, also mediates nonenzymatic interactions between lipoproteins and heparan sulfate ...LPL increases LDL binding to cells, bovine milk LPL was added to upregulated and ... See full document
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Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
... Lipoprotein lipase (LPL)-deficient mice have been created by gene targeting in embryonic stem cells. At birth, homozygous knockout pups have threefold higher triglycerides and sevenfold higher VLDL cholesterol ... See full document
15
Regulation of G protein alpha i2 subunit expression by oxidized low density lipoprotein
... Oxidized low-density lipoprotein (LDL) inhibits signalling pathways mediated by pertussis toxin-sensitive guanine nucleotide-binding proteins (Gi ...with oxidized LDL (0-100 ... See full document
8
BMP4 is increased in the aortas of diabetic ApoE knockout mice and enhances uptake of oxidized low density lipoprotein into peritoneal macrophages
... oxLDL uptake, when compared with controls (12% of the total) (Figure ...oxLDL uptake was significantly inhibited by 50% when cells were treated with ...the uptake of oxLDL into macrophages in ... See full document
9
Low Density Lipoprotein: A METABOLIC PATHWAY FOR RETURN OF CHOLESTEROL TO THE SPLANCHNIC BED
... very low density lipoprotein cholesterol (mean AV difference − 3 mg/100 ml, P < ...cholesterol, high density lipoprotein cholesterol, or low density ... See full document
8
High Density Lipoprotein Metabolism in Man
... I-high density lipoprotein (HDL) was examined in a total of 14 studies in eight normal volunteers in an attempt to determine the metabolic relationship between apolipoproteins A-I (apoA-I) and A-II ... See full document
14
Dapagliflozin decreases small dense low-density lipoprotein-cholesterol and increases high-density lipoprotein 2-cholesterol in patients with type 2 diabetes: comparison with sitagliptin
... LDL-C can be fractionated into large buoyant (lb) and small dense (sd) particles based on size and density. An abundance of clinical evidence has shown that sd LDL-C particles are more atherogenic than lb LDL-C ... See full document
13
Oxidized Low-Density-Lipoprotein Uptake by Renal Tubular Epithelial Cells Causes Alterations of Plasma Membrane Microdomain Composition and Signaling
... particles were isolated from 300-400 ml plasma of healthy donors by sequential KBr-density gradient ultracentrifugation (UC) steps (rotor 70Ti, Beckman). Potassium bromide was added according to this calculation ... See full document
8
Oxidized Low-Density Lipoprotein Is a Novel Predictor of Interferon Responsiveness in Chronic Hepatitis C Infection
... (SR-BI). Oxidized low density lipoprotein (oxLDL) inhibits the interaction between HCV and SR-BI in a noncompetitive ...SVR. Oxidized LDL did not corre- late with markers of inflammation ... See full document
11
Effect of Lycopene on Formation of Low Density Lipoprotein-Copper Complex in Copper Catalyzed Peroxidation of Low Density Lipoprotein, as in vitro Experiment
... igh blood cholesterol level is a major risk factor for atherosclerosis and it is associated with high blood concentration of low density lipoprotein (LDL). Excessive LDL deposits in the ... See full document
6
Reduced uptake of oxidized low density lipoproteins in monocyte derived macrophages from CD36 deficient subjects
... with CD36 deficiency than those from normal ...the uptake of 125I-OxLDL was suppressed by OKM5, an antibody against CD36, by 53% in normal control macrophages, but not in the CD36-deficient ... See full document
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