[PDF] Top 20 Co localization of neural cell adhesion molecule and fibroblast growth factor receptor 2 in early embryo development
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Co localization of neural cell adhesion molecule and fibroblast growth factor receptor 2 in early embryo development
... and 2-cell embryos ...and 2-cell embryos ...to 2-cell embryos ...preimplantation development (Wang et ...are co-expressed in almost all tissues at different ...to ... See full document
8
The Characterization of the Fibroblast Growth Factor Receptor Substrate 3 and its role in Regulating Microtubule Dynamics and Molecular Transport in the Brain
... to neural tissues (Hryciw et ...cortical development. FRS3 expression is detectable as early as E12, and coincides with the expression of β III tubulin, a neuron specific ...weak ... See full document
132
Fasciclin 2, the Drosophila orthologue of neural cell adhesion molecule, inhibits EGF receptor signalling
... epidermal growth factor receptor (EGFR) signalling ...in development (Shilo, 2003; Domínguez et ...normal development, deregulation of ErbB activity is implicated in many human ... See full document
9
Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases
... Liver cirrhosis, the most advanced stage of fibrosis, con- notes not only more scarring than that from fibrosis alone, but also distortion of the liver parenchyma associ- ated with septae and nodule formation, altered ... See full document
8
Mutations in the phosphatidylinositol 3 kinase pathway: role in tumor progression and therapeutic implications in breast cancer
... and growth-promoting roles, the PI3K pathway interacts with ER directly [33] and ...by growth factor RTK signaling is reciprocated in a feed-forward fashion, whereby ER promotes the transcription of ... See full document
12
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2+/S252W mouse
... and IIIc alternative transcripts in hypomorphic mutant mice were generally reduced by 16% to 41%, when compared with those of the normal transcripts in multiple tissues examined, including lung, liver, kidney and stomach ... See full document
12
Identification of key biomarkers associated with cell adhesion in multiple myeloma by integrated bioinformatics analysis
... CAMs: Cell adhesion molecules; CDH1: Cadherin 1; DAVID: Database for annotation, visualization and inte- grated discovery; DEG: Differentially expressed gene; DSS: Disease-specific survival; ECM: ... See full document
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Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice
... basic fibroblast growth factor; bFGFR: basic fibroblast growth factor receptor; BMSC: bone marrow-derived mesenchymal stem cell; BSA: bovine serum albumin; CCK-8: ... See full document
15
The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis
... BRG1-associated factor 60; Cdc42: cell division control protein 42; CDK: cyclin-dependent kinase; Cdo: cell adhesion molecule-related/downregulated by oncogenes; CIP/KIP: cyclin- ... See full document
18
Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity
... (Fig. 2, ...(Fig. 2, ...(Fig. 2, A and B, basal), as shown by the population distribution of the fluorescence lifetimes being largely at longer lifetimes (right shifted) than that of isolated GFP at ... See full document
12
Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike?
... endothelial growth factor (VEGF)-A, a key player in the angiogenesis ...placental growth factor, which could enable escape from VEGF-A-targeted angiogenesis ... See full document
13
Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning
... BMSC growth medium comprising of αMEM (Gibco) plus 15 % fetal bovine serum (FBS; Bio- sera, UK) on tissue culture plates ...in growth medium and plated onto new tissue culture plates at 50,000 cells/cm ... See full document
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Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities
... particularly highly expressed at sites of inflammation and tissue repair. Increased CCN1 levels have been found in a number of chronic inflammatory diseases in- cluding colitis [46], rheumatoid arthritis [47], and ath- ... See full document
13
Cell cell signaling and adhesion in phagocytosis and early development of Dictyostelium
... particle adhesion, such that a phagocytic cup is formed, and further actin polymerization at the distal border of the cup, in order for the particle to be totally ...(Fig. 2) (Peracino et ...particle ... See full document
10
Ally to adversary: mesenchymal stem cells and their transformation in leukaemia
... This exemplifies the role that a defective microenviron- ment may play in initiating neoplasms. In another study in mice, a link between deletion of Rb (Retinoblastoma) gene in both HSC as well as stromal cells ... See full document
9
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
... in cell proliferation [12, 19, 20], survival [21], differentiation [22] and drug resistance ...substrate 2 (FRS2) is a key adaptor protein that binds to the juxtamembrane region of FGFR2 through its ... See full document
9
Link between neurodegeneration and trabecular meshwork injury in glaucomatous patients
... in cell homeostasis since it is involved in both prosurvival (intralysosomal proteolysis of autophagy and endocytosed substrates) and prodeath (proteolysis of cyto- solic substrates) processes ...TM cell ... See full document
7
The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study
... was eliminated with 3% peroxide–methanol at room tempera- ture for 5 minutes. Nonspecific staining was avoided with blocking buffer (normal goat serum) at room temperature for 20 minutes. The sections were incubated with ... See full document
11
Current research in perineural invasion of cholangiocarcinoma
... acetylcholine receptor is expressed in the gallbladder cancer cell line Mz-ChA- 1; while cultivating the muscarinic AchR receptor ago- nist carbonic acid bilineurin with the gallbladder cancer cells, ... See full document
7
The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor
... FGF receptor ligand system could change due to the concentration of FGF-2, particularly since there is evidence for FGF-2 possessing two binding sites for the FGFR of different affinities [24] and ... See full document
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