[PDF] Top 20 Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung
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Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung
... with lung adenocarcinoma enrolled in the lung eQTL mapping study was selected for validation by quantitative real-time PCR ...non-tumor lung specimens from sixteen individuals with genotype CC and ... See full document
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Genetic variants in regulatory regions of microRNAs are associated with lung cancer risk
... Genetic variants in regulatory regions of some miRNAs might be associated with lung cancer risk and ...cell lung cancer (NSCLC) cases and 1982 controls to evaluate the ... See full document
9
Genetic variants in lncRNA HOTAIR are associated with lung cancer susceptibility in a Chinese Han population in China: a case–control study
... with lung cancer ...developing lung cancer, and in stratified analyses for pathologic type of lung cancer, sex, and smoking status, the associations between rs4759314 ... See full document
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Genetic variants of miRNA sequences and non–small cell lung cancer survival
... and cancer biology has been demonstrated ...to cancer susceptibility and ...breast cancer (15), which was further supported in a spontaneous mouse model of chronic lymphocytic leukemia ... See full document
10
Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells
... p62 expression under ER stress in NCI-H446 ...the expression of Beclin 1 and LC3II increased, but p62 expression de- creased by TM treatment, which indicates that autophagy was triggered under ER ... See full document
5
Original Article Correlation between survivin genetic polymorphisms and lung cancer susceptibility
... with lung cancer via histopathology were collected from Linyi People’s Hospital, aging from 29 to 67 with an average age of ...of genetic disease or cancers whose age were from 31 to 70 with an ... See full document
5
BFSSGA: Enhancing the Performance of Genetic Algorithm using Boosted Filtering Approach
... Filter methods are easier and simpler to implement but they do not consider the combined classification power resulting from gene interactions. Interactions among genes are an important consideration as biological states ... See full document
6
Original Article Bioinformatic analysis of the role of MNAT1 in the progression of lung cancer and its correlation with the prognosis of patients
... of cancer patients is gradually increasing. Global attention to cancer patients has been widely ...to cancer patients and diabetic patients [12], China has also proposed a precise medical strategic ... See full document
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MUTYH Gln324His gene polymorphism and genetic susceptibility for lung cancer in a Japanese population
... Genetic variation in DNA repair genes are thought to modulate DNA repair capacity and are suggested to be related to cancer risk [2]. The base excision repair (BER) pathway, one of the DNA repair ... See full document
6
Low Dose of IL 12 Stimulates T Cell Response in Cultures of PBMCs Derived from Non Small Cell Lung Cancer Patients
... the expression of IFN on CD4 T cells after isolation and IL-12 ...of cancer cell ...against cancer has been demonstrated [24], we studied the ability of low doses of IL-12 to down-regulate T ... See full document
6
Original Article Serum miR-1826 expression serves as a diagnostic biomarker and inhibits cell proliferation, migration, and invasion of lung cancer
... Lung cancer, a common primary malignant tumor, is a leading cause of cancer-related de- aths, worldwide, with high morbidity and mor- tality rates [1, ...of lung cancer, non-small cell ... See full document
8
The role of desmosomes in carcinogenesis
... PKPs, which have been characterized as desmosomal plaque proteins, stabilize desmosomal cadherins at the plasma membrane and interact with the cytoskeletal linker protein DSP. They are predominantly expressed in ... See full document
5
<p>EFEMP2 Suppresses the Invasion of Lung Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition (EMT) and Down-Regulating MMPs</p>
... bladder cancer and endometrial carcinoma, EFEMP2 played inhibitory roles in the process of ...bladder cancer cells and EMT process, while EFEMP2 down- regulation could promote the proliferation, invasion ... See full document
22
Negative correlation of cytoplasm TIMP3 with miR-222 indicates a good prognosis for NSCLC
... and its underlying mechanism may be consistent with the above, and it exerts its effects in the cytoplasm. However, there is an interesting phenomenon in this study. The expres- sion of TIMP3 is negatively correlated ... See full document
7
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway
... p-AKT expression was inhibited in NSCLC cells with LPCAT1 ...p-AKT expression and cell prolif- eration was abolished in NSCLC cells with depletion of ...MYC expression decreased in LPCAT1 knockdown ... See full document
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Molecular Mechanisms of Cancer-Induced Sleep Disruption
... genetic and environmental circadian disruption on tumor development in a model of lung cancer. 703[r] ... See full document
37
RanGTPase: A Candidate for Myc Mediated Cancer Progression
... a cancer therapeutic target has been described in recent stud- ies ...in cancer cell lines and tumor tis- sues at both the mRNA and protein levels compared with normal counterparts ...Ran expression ... See full document
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Original Article Human beta-defensin 2 promotes the proliferation of lung cancer cells through ATP-binding cassette transporter G2
... hBD2 expression [5-7]. Indeed, hBD2 level in the lung tissue and serum is elevated in patients with lung ...between lung cancer and hBD2 has not been clearly ...on lung ... See full document
6
Molecular epidemiology of lung cancer in the Liverpool lung project (LLP) cohort
... Anderson cancer centre 48 ...developing lung cancer 48 ...of cancer, asbestos and wood dust exposure, previous emphysema and previous hay fever 48 ... See full document
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... breast cancer [31]. In the analyzed cases of lung cancer, a high level of BRD4 was considered to be correlated with a poor prog- nosis of non-small cell lung cancer (NSCLC) and ... See full document
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