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[PDF] Top 20 Lung disease in mice with cystic fibrosis

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Lung disease in mice with cystic fibrosis

Lung disease in mice with cystic fibrosis

... Histological changes in CF mouse lungs were consistently observed, and were obvious even in the lungs of animals as young as 30 d. Low power views, using light microscopy, showed that the congenic animals develop acinar ... See full document

11

Status of gene therapy for cystic fibrosis lung disease

Status of gene therapy for cystic fibrosis lung disease

... of cystic fibrosis should be a “natural”: Cystic fibrosis (CF) is a recessive disease associated with loss of function mutations in the CF transmembrane conductance regulator (CFTR) ... See full document

6

The genesis of cystic fibrosis lung disease

The genesis of cystic fibrosis lung disease

... Cystic fibrosis (CF), as Bals et ...CF lung disease has been refractory to the onslaught of molecular/cellular research that has clarified so many other aspects of ...CF lung ... See full document

5

BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung disease

BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung disease

... CF-like lung disease, and perhaps not unexpectedly, analysis of lung tissues revealed that there were no readily detectable differences in the staining intensity or localization of BPIF proteins ... See full document

10

Microstructural alterations of sputum in cystic fibrosis lung disease

Microstructural alterations of sputum in cystic fibrosis lung disease

... Cystic fibrosis (CF) is one of the most common genetic disorders that primarily causes life-threatening lung disease ...in lung function and shorter survival in CF ...in cystic ... See full document

13

Potential of anti-inflammatory treatment for cystic fibrosis lung disease

Potential of anti-inflammatory treatment for cystic fibrosis lung disease

... Abstract: Cystic fibrosis (CF) is the most common life-shortening genetic disorder in Caucasians. With improved diagnosis and treatment, survival has steadily increased. Unfortunately, the overwhelming ... See full document

14

Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease

Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease

... Chronic lung disease remains the major cause of morbidity and mortality in patients with cystic fibrosis ...CF lung disease remains ...ENaC-Tg) mice featuring CF-like ... See full document

7

The innate immune system in cystic fibrosis lung disease

The innate immune system in cystic fibrosis lung disease

... The role of primary and secondary defects of the innate host defense system in the CF lung. A number of hypotheses have been proposed to explain how a defect of CFTR results in a breach of the innate immune system ... See full document

6

Polysomnographic Markers in Children With Cystic Fibrosis Lung Disease

Polysomnographic Markers in Children With Cystic Fibrosis Lung Disease

... to lung disease severity because not all subjects had available PFTs with small-airway disease parameters, lung volume measurements, diffusion capacity, or chest imaging studies that coincided ... See full document

9

Non-invasive ventilation (NIV) as an aid to rehabilitation in acute respiratory disease

Non-invasive ventilation (NIV) as an aid to rehabilitation in acute respiratory disease

... chronic lung disease (including Cystic Fibrosis [CF], Bronchiectasis), who were judged by the clinical physiotherapy team to have significantly impaired exercise capacity and were not expected ... See full document

8

Impact of pseudomonas aeruginosa Liverpool epidemic strain (LES) on cystic fibrosis patients

Impact of pseudomonas aeruginosa Liverpool epidemic strain (LES) on cystic fibrosis patients

... with lung disease, most notably CF ...CF lung is a very hostile and heterogeneous environment in which the colonising microorganisms have to adapt to ... See full document

171

Monitoring clinical and microbiological evolution of a cystic fibrosis patient over 26 years: experience of a Brazilian CF Centre

Monitoring clinical and microbiological evolution of a cystic fibrosis patient over 26 years: experience of a Brazilian CF Centre

... the lung function steadly declined in the last 3 years, coinciding with the moment of CFRD ...worsening lung function [14]. The deterioration of the reported CF patient lung function overlaps with ... See full document

5

Cystic fibrosis overview and update on infant care

Cystic fibrosis overview and update on infant care

... for Cystic Fibrosis [AREST-CF]) published a study [42] in which 57 infants with median age of ...of lung disease with bacterial infection was ...structural lung-disease were ... See full document

10

Mycobacterial infections in a large Virginia hospital, 2001 2009

Mycobacterial infections in a large Virginia hospital, 2001 2009

... NTM lung species, including age, gender, chronic obstructive pulmonary disease, cystic fibrosis, other lung diseases, diabetes, end stage renal disease, collagen vascular ... See full document

7

Molecular screening of R117H mutation in non caucasian cystic fibrosis patients in the north of Iran

Molecular screening of R117H mutation in non caucasian cystic fibrosis patients in the north of Iran

... including lung epithelium, submucosal gland of intestine, stomach, pancreas, gallbladder, liver, sweat ducts and reproductive ...obstructive lung disease and chronic bacterial infections leading to ... See full document

6

No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis

No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis

... acute lung disease were excluded ...with cystic fibrosis was recently discussed [15– ...the lung func- tion (FEV1) before implementation of the eradication protocol were similar to ... See full document

6

In vivo monitoring of lung inflammation in CFTR deficient mice

In vivo monitoring of lung inflammation in CFTR deficient mice

... Experimentally, lung inflammation in laboratory animals is usually detected by the presence of inflam- matory markers, such as immune cells and cytokines, in the bronchoalveolar lavage fluid (BALF) of sacrificed ... See full document

9

Myocardial infarction in an adult with cystic fibrosis and heart and lung transplant

Myocardial infarction in an adult with cystic fibrosis and heart and lung transplant

... The development of CTV is thought to be due to a combination of an immune-mediated process and non- immunologic risk factors resulting in endothelial injury and subsequent fibroelastic proliferation of the intima [6]. ... See full document

5

Nutritional advances in patients with respiratory diseases

Nutritional advances in patients with respiratory diseases

... in disease management from diagnosis and treatment to prediction and ...for disease prevention but also contributing to heterogeneity in disease progression and ...pulmonary disease (COPD), ... See full document

6

Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1 Year Period

Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1 Year Period

... ABSTRACT Cystic fibrosis (CF) lung microbiota composition has recently been rede- fined by the application of next-generation sequencing (NGS) tools, identifying, among others, previously undescribed ... See full document

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