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[PDF] Top 20 Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

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Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

... the randomized phase (week 8 to week ...on treatment as usual for the duration of the ...of treatment settings and enhance generalizability, potential participants were recruited through a variety of ... See full document

11

A randomized, double blind, placebo controlled trial to assess the efficacy of topiramate in the treatment of post traumatic stress disorder

A randomized, double blind, placebo controlled trial to assess the efficacy of topiramate in the treatment of post traumatic stress disorder

... of bipolar, psychotic, borderline per- sonality disorder; substance dependence or abuse (exclud- ing nicotine and caffeine) in the previous 6 months; 2) serious or unstable concurrent illness; history of ... See full document

7

The Efficacy of Probiotics for Treatment of Bipolar Disorder- Type 1: A Randomized, Double-Blind, Placebo-Controlled Trial

The Efficacy of Probiotics for Treatment of Bipolar Disorder- Type 1: A Randomized, Double-Blind, Placebo-Controlled Trial

... including bipolar disorders (20, ...in bipolar patients than in the nonbipolar ...and placebo group; however, immunomodulatory effects from probiotics were noted ...of bipolar patients and ... See full document

7

Rucaparib: a novel PARP inhibitor for <em>BRCA</em> advanced ovarian cancer

Rucaparib: a novel PARP inhibitor for&nbsp;<em>BRCA</em>&nbsp;advanced ovarian cancer

... transaminase (ALT). The maximum tolerated dose was not reached and 600 mg bid was established as RP2D based on the safety and pharmacokinetic assessment. This study also confirmed that rucaparib can be taken with or ... See full document

13

Baclofen for maintenance treatment of opioid dependence: A randomized double blind placebo controlled clinical trial [ISRCTN32121581]

Baclofen for maintenance treatment of opioid dependence: A randomized double blind placebo controlled clinical trial [ISRCTN32121581]

... first randomized, double blind, placebo-controlled clinical trial evaluating the efficacy of baclofen in the mainte- nance treatment of opioid ...to placebo in ... See full document

10

New and emerging treatments for ulcerative colitis: a focus on vedolizumab

New and emerging treatments for ulcerative colitis: a focus on vedolizumab

... to enroll in an 18-month open-label safety study. Primary endpoints included disease activity using the PMS and fecal calprotectin to provide quantitative analysis of mucosal inflammation: .50 µ g/g demonstrated active ... See full document

8

Clinical role of brexpiprazole in depression and schizophrenia

Clinical role of brexpiprazole in depression and schizophrenia

... both treatment populations, it is recommended that those patients with moderate to severe hepatic or end- stage renal impairment should be prescribed no more than 3 mg ... See full document

8

Review of depot aripiprazole for schizophrenia

Review of depot aripiprazole for schizophrenia

... Abstract: Improving outcomes in schizophrenia generally requires an improvement in medication adherence. One of the most effective interventions to improve adherence is the use of depot formulations of antipsychotic ... See full document

7

Revisiting loxapine: a systematic review

Revisiting loxapine: a systematic review

... the treatment of schizophrenia since the mid-1970s [12,13] and is nowadays quite widely used in countries like France or ...acute treatment of agitation in adult patients with schizophrenia or ... See full document

8

Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study

Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study

... A potential limitation of the present study is that LOCF was used in the analyses. LOCF may bias an estimate of the treatment and underestimate variability of the estimated result. Sensitivity analyses have been ... See full document

12

Efficacy of ketamine in the rapid treatment of  major depressive disorder: a meta-analysis of randomized, double-blind, placebo-controlled studies

Efficacy of ketamine in the rapid treatment of major depressive disorder: a meta-analysis of randomized, double-blind, placebo-controlled studies

... six were excluded after two reviewers independently examined the full texts due to the following reasons: no control group; part of the recruited patients had other psy- chiatry disorders; using ketamine first for all ... See full document

9

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... known history of chronic illnesses, such as chronic liver or renal diseases, congenital heart diseases, immune deficiency or malig- nancy, were excluded. Children who regu- larly took vitamins or minerals, or those who ... See full document

6

Critical analysis of the use of onabotulinumtoxinA (botulinum toxin type A) in migraine

Critical analysis of the use of onabotulinumtoxinA (botulinum toxin type A) in migraine

... soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARe) complex: the vesicle-associated membrane protein (vAMP or synaptobrevin) and the membrane-bound syntaxin and synaptosome- associated ... See full document

14

Approach to managing behavioural disturbances in dementia.

Approach to managing behavioural disturbances in dementia.

... varied from 0 to 67%, and antipsychotics as a class had only a modest benefi t. Th e derived treatment eff ect size was estimated at 18% (ie, only 18% of patients had better results with neuroleptics than with ... See full document

9

Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind, placebo-controlled trial

Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind, placebo-controlled trial

... of treatment for TN, and may be an efficient, safe and novel strategy for TN treatment ...large randomized controlled trial and relevant data ex- cept our study in 2012 [6], and the ... See full document

6

Effects of Ghrelin Treatment on Exercise Capacity in Underweight COPD Patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment

Effects of Ghrelin Treatment on Exercise Capacity in Underweight COPD Patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment

... by the protocol of 2-min increments to 10 W was larger than that measured by the protocol with the ramp rate of 5 W/min (mean difference: by 2-min increments to 10 W, 1.4 mL/kg/min versus with a ramp rate of 5 W/min, 1.1 ... See full document

10

Future prospects in the treatment of erectile dysfunction: focus on avanafil

Future prospects in the treatment of erectile dysfunction: focus on avanafil

... early treatment of ED consisted of several psycho- logical and hormonal strategies and the use of penile implants and vacuum ...the treatment of ED and have become first-line treatment due to their ... See full document

9

Combotherapy and current concepts as well as future strategies for the treatment of Alzheimer&amp;#39;s disease

Combotherapy and current concepts as well as future strategies for the treatment of Alzheimer&#39;s disease

... of this disease has moved from proteins to organelles (eg, the mitochondria), at least from the perspective of some researchers. In contrast, in the era of the genome, some of the pathognomonic genes for AD have been ... See full document

13

Pilocarpine application on treatment of xerostomia: state of the art

Pilocarpine application on treatment of xerostomia: state of the art

... the treatment of Sjogren’s syndrome, we can find artificial saliva that is rarely used by patients because it leads to only few minutes of improvement, or bromhexine and anetholtrithione, that are often used to ... See full document

7

Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial

Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial

... between treatment groups using the van Elteren's test, a type of stratified Wilcoxon test, with baseline incontinence severity as the stratifica- tion ...scores, treatment, site, and baseline incontinence ... See full document

9

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