[PDF] Top 20 Manipulating Selectivity and Reactivity in Palladium-Catalyzed Oxidation Reactions

... Wacker oxidation combined with established enantioselective methodologies enables a powerful strategy to access versatile enantioenriched building ...iridium- catalyzed allylic substitution ...Wacker ... See full document

... Still other C 1 symmetric ligands rely on the chirogenicity of coordinating metal atoms for asymmetric induction. Such ligands offer the potential advantage of having the chirality closer to the metal center, rather than ... See full document

... the selectivity factor is usually determined by measuring the total conversion of starting material to product and the enantiomeric excess of the recovered starting ...optimum selectivity, the chiral ... See full document

... Introduction Palladium represents an essential tool for organic synthesis due to its wide spread use in catalysis for the construction of challenging types of C−C and C−heteroatom ...result, ... See full document

... the palladium-catalyzed oxidative kinetic resolution of secondary alcohols has led to the development of four distinct sets of conditions for this process (Table ...conditions. Reactions performed in ... See full document

... Comparison of these two approaches reveals several fundamental differences. If, at least in theory, any C-H bond may be considered a potential site of functionalization, the synthetic chemist has a tremendously expanded ... See full document

... 7 indicate that, when covalently bonding Pd complexes with ligands to silica support, the catalysts can provide good yield and selectivity for cross-coupling reaction. Moreover, the heterogeneity test for that ... See full document

... dissertation, palladium- and platinum-catalyzed C–H arylation reactions were explored to achieve this ...chemical reactivity and represent a step toward the ultimate goal of predicting the ... See full document

... nucleophilic reagents and hydrogen source which might serve as a better convenient solvent than conventional system. The most convenient approach to construct a catalyst into aqueous phase reaction has been to design ... See full document

... Scheme 1.19: Intramolecular direct arylation 1.2.3. Effects of ligands: Phosphine ligands Ligands are usually used in combination with Pd catalyst to achieve selectivity and reactivity. In oxidative ... See full document

... cross-coupling reactions, ligands have had an enormous influence on many aspects of palladium-mediated processes, such as the ability to prolong catalyst lifetime, influence site selectivity or ... See full document

... conditions, various functional groups such as acetyl, formyl, and cyano groups were well tolerated. When electron-de ficient arylsulfoniums 1c −1g were employed, 10−15% yields of aryl sul fides 4c−4g were formed via ... See full document

... Donor 2, bearing the silylidene group is the most reactive of the studied glucosamine donors. It also is slightly more flexible than the benzylidene restricted donors, and these two factors allow the activated donor to ... See full document

... intramolecular reactions with various aryl halides were developed employing a general catalytic system based on Pd(OAc) 2 with PCy 3 ·HBF 4 as ligand and K 2 CO 3 as ... See full document

... the oxidation site due to the presence of the different oxidation- prone ...monitor oxidation progress (Table ...the oxidation of 1 even more, resulting in a decrease in turnover number (TON) ... See full document

... the reactivity of parent amido complexes and other transition metal amido complexes, especially as the reactivity relates to catalytic ...possible reactions with amido complexes can be ...with ... See full document

... All reactions were performed in oven-dried (140 °C) or flame dried glassware under an atmosphere of dry nitrogen or argon, unless noted. Reaction solvents tetrahydrofuran (Fisher, HPLC grade), diethyl ether ... See full document

... Then, 1,2,3-trifluorobenzene was coupled with a set of (hetero)aryl bromides in the presence of 2 mol% Pd(OAc) 2 , KOPiv as the base in DMA (Scheme 2). Very regioselective C4-arylations and quite good yields in 2-7 were ... See full document

... methane oxidation was catalyzed by platinum, but at that time the effect of the catalyst was not well ...of reactions occurring on a surface. Heterogeneous catalytic reactions have been ... See full document

... In line with these new developments on the use of bulky phosphine ligands in palladium-catalyzed reactions of aryl chlorides, a number of research groups have described other ligands tha[r] ... See full document