[PDF] Top 20 Ras1-Mediated Modulation of Drosophila Homeotic Function in Cell and Segment Identity

... Since Gapl is generally viewed as a specific antagonist of Rasl' function, this supported our interpretation that Rasl is the relevant locus in the 85D11-14 interval that modif[r] ... See full document

... predominant homeotic gene expressed in the ground state PS4, it does not appear to play a major role in the formation of this class of sense ...Antp function affects the sense organs in PS4 and 5 however ... See full document

... in Drosophila (Sollars et ...example, homeotic axial transformations and Hox expression defects of Mll-deficient mice and Bmi1-deficient mice are rescued when function of both genes is removed ... See full document

... In Drosophila, changing the two central bases from CC to TA switches the in vivo specificity of Repeat 3 from a LAB to a DFD responsive element (Chan et ... See full document

... appropriate identity of each ...mesothoracic identity (Ingham, 1985) –thus clones in dorsal structures, such as the eye or haltere differentiate notal or wing tissue whereas clones in ventral structures, ... See full document

... Distinctive cell identities such as sex comb teeth have long been used as markers of homeotic function in segmental ...adult segment offers a useful model for studying how cell ... See full document

... The Ras superfamily contains five specific groups of structurally related but functionally distinct signalling proteins. The Ras (Rat sarcoma) family were the first proteins of the Ras superfamily to be described, due in ... See full document

... lary segment indicated by ar- ...maxillary segment except in a few cells at the posterior edge of the lobe that are known to express Scr pro- tein (Riley et ... See full document

... isolated cell, but a cluster o f contiguous sensory precursor cells (SPCs) that coexist instead o f competing by lateral ...(In Drosophila, SMCs likewise develop in contiguity, exceptionally, at the wing ... See full document

... SCHUPBACII, 1992 The torpedo (DER) receptor tyrosine kinase is required at multiple times during Drosophila embryogenesis. AYERS, 1992 chickadee encodes a profilin requ[r] ... See full document

... Figure 2.—Molecular ge- netic map of the distal re- gion of the ANTC. The top shows the location of the transcription units in 210 kb of genomic DNA from poly- tene chromosome bands 84B1–2. Both the P1 and P2 ... See full document

... mesangial cell proliferation which showing acute and chronic glomerulonephritis is consistent with multiple inflammatory episodes similar to that seen in systemic lupus erythematosus (SLE) (Li et ...T cell ... See full document

... If the mutant and wild-type alleles of aristapedia control antennal prepatterns, an antenna which is predominantly one type of tissue should have the correspond- ing prepattern.. A [r] ... See full document

... ABBREVIATIONS BSA Bovine serum albumin CFA Complete Freunds Adjuvant CNS Central Nervous System Con A Concanavalin A CSF Cerebrospinal fluid DFO Desferrioxamine DMEM Dulbeccos modified E[r] ... See full document

... The discovery of the striking positional conservation between the Antennapedia and Bithorax homeotic gene complexes (ANT-C and BX-C) in Drosophila melanogaster and th[r] ... See full document

... The brahma gene is required for activation of the homeotic genes of the Antennapedia and bithorax complexes in Drosophila.. We have isolated and characterized 21 mutations in brahm[r] ... See full document

... of cell- line and embryonic tissue ...the cell-line extracts ...HeLa, cell- lines. It was not detected in the T-lymphocyte derived JM cell-line, although no control was available for the ... See full document

... in early embryos and in cultured cells by chromatin immu- noprecipitation (Holohan et al. 2007; Nègre et al. 2010). CTCF is a zinc-finger DNA-binding protein proposed to be involved with intrachromosomal looping and with ... See full document

... same cell types Histology: Adult fly eyes were prepared for thin section (R3, R4, R7, and cone cells), which causes a loss of analysis by fixing in 2% glutaraldehyde and 2% osmium tetrox- photoreceptor cells and ... See full document

... The regulation of segment specific homeotic genes by the trithorax and polycomb sets of genes: T h e homeotic transformations caused by mutations in any one of the [r] ... See full document